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收藏Acquired BTK mutations associated with resistance to noncovalent BTK inhibitors
Qi, Jialei; Endres, Sascha; Yosifov, Deyan Yordanov; Tausch, Eugen; Dheenadayalan, Rashmi Priyadharshini; Gao, Xiang; Mueller, Annika; Schneider, Christof; Mertens, Daniel; Gierschik, Peter; Wist, Martin; Jebaraj, Billy Michael Chelliah; Stilgenbauer, Stephan 分享 收藏 Rare Antagonistic Leptin Variants and Severe, Early-Onset ObesityFuncke, Jan-Bernd; Moepps, Barbara; Roos, Julian; von Schnurbein, Julia; Verstraete, Kenneth; Froehlich-Reiterer, Elke; Kohlsdorf, Katja; Nunziata, Adriana; Brandt, Stephanie; Tsirigotaki, Alexandra; Dansercoer, Ann; Suppan, Elisabeth; Haris, Basma; Debatin, Klaus-Michael; Savvides, Savvas N.; Farooqi, I. Sadaf; Hussain, Khalid; Gierschik, Peter; Fischer-Posovszky, Pamela; Wabitsch, Martin 分享 收藏 Membrane Environment Exerts an Important Influence on Rac-Mediated Activation of Phospholipase Cγ2Everett, Katy L.; Buehler, Anja; Bunney, Tom D.; Margineanu, Anca; Baxendale, Rhona W.; Vatter, Petra; Retlich, Michael; Walliser, Claudia; Manning, Hugh B.; Neil, Mark A. A.; Dunsby, Christopher; French, Paul M. W.; Gierschik, Peter; Katan, Matilda 分享 收藏 Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORASOTULIN中的复合杂合变体与暴发性非典型迟发性ORAS相关Zinngrebe, Julia; Moepps, Barbara; Monecke, Thomas; Gierschik, Peter; Schlichtig, Ferdinand; Barth, Thomas F. E.; Strauss, Gudrun; Boldrin, Elena; Posovszky, Carsten; Schulz, Ansgar; Beringer, Ortraud; Rieser, Eva; Jacobsen, Eva-Maria; Lorenz, Myriam Ricarda; Schwarz, Klaus; Pannicke, Ulrich; Walczak, Henning; Niessing, Dierk; Schuetz, Catharina; Fischer-Posovszky, Pamela; Debatin, Klaus-Michael 分享 收藏 Noncatalytic Bruton's tyrosine kinase activates PLC?2 variants mediating ibrutinib resistance in human chronic lymphocytic leukemia cellsWist, Martin; Meier, Laura; Gutman, Orit; Haas, Jennifer; Endres, Sascha; Zhou, Yuan; Roesler, Reinhild; Wiese, Sebastian; Stilgenbauer, Stephan; Hobeika, Elias; Henis, Yoav I.; Gierschik, Peter; Walliser, Claudia 分享 收藏 分享 收藏 Measurement of immunofunctional leptin to detect and monitor patients with functional leptin deficiencyWabitsch, Martin; Pridzun, Lutz; Ranke, Michael; von Schnurbein, Julia; Moss, Anja; Brandt, Stephanie; Kohlsdorf, Katja; Moepps, Barbara; Schaab, Michael; Funcke, Jan-Bernd; Gierschik, Peter; Fischer-Posovszky, Pamela; Flehmig, Bertram; Kratzsch, Juergen 分享 收藏 Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are PredictiveTaudien, Stefan; Lausser, Ludwig; Giamarellos-Bourboulis, Evangelos J.; Sponholz, Christoph; Schoeneweck, Franziska; Felder, Marius; Schirra, Lyn-Rouven; Schmid, Florian; Gogos, Charalambos; Groth, Susann; Petersen, Britt-Sabina; Franke, Andre; Lieb, Wolfgang; Huse, Klaus; Zipfel, Peter F.; Kurzai, Oliver; Moepps, Barbara; Gierschik, Peter; Bauer, Michael; Scherag, Andre; Kestler, Hans A.; Platzer, Matthias 分享 收藏 The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 ProteinWalliser, Claudia; Hermkes, Elisabeth; Schade, Anja; Wiese, Sebastian; Deinzer, Julia; Zapatka, Marc; Desire, Laurent; Mertens, Daniel; Stilgenbauer, Stephan; Gierschik, Peter 分享 收藏 Cool-temperature-mediated activation of phospholipase C-γ2 in the human hereditary disease PLAIDSchade, Anja; Walliser, Claudia; Wist, Martin; Haas, Jennifer; Vatter, Petra; Kraus, Johann M.; Filingeri, Davide; Havenith, George; Kestler, Hans A.; Milner, Joshua D.; Gierschik, Peter 分享 收藏 Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin GeneWabitsch, Martin; Funcke, Jan-Bernd; von Schnurbein, Julia; Denzer, Friederike; Lahr, Georgia; Mazen, Inas; El-Gammal, Mona; Denzer, Christian; Moss, Anja; Debatin, Klaus-Michael; Gierschik, Peter; Mistry, Vanisha; Keogh, Julia M.; Farooqi, I. Sadaf; Moepps, Barbara; Fischer-Posovszky, Pamela 分享 收藏 Rac-mediated Stimulation of Phospholipase Cγ2 Amplifies B Cell Receptor-induced Calcium SignalingWalliser, Claudia; Tron, Kyrylo; Clauss, Karen; Gutman, Orit; Kobitski, Andrei Yu.; Retlich, Michael; Schade, Anja; Roecker, Carlheinz; Henis, Yoav I.; Nienhaus, G. Ulrich; Gierschik, Peter 分享 收藏 Discovery and Characterization of an Endogenous CXCR4 AntagonistZirafi, Onofrio; Kim, Kyeong-Ae; Staendker, Ludger; Mohr, Katharina B.; Sauter, Daniel; Heigele, Anke; Kluge, Silvia F.; Wiercinska, Eliza; Chudziak, Doreen; Richter, Rudolf; Moepps, Barbara; Gierschik, Peter; Vas, Virag; Geiger, Hartmut; Lamla, Markus; Weil, Tanja; Burster, Timo; Zgraja, Andreas; Daubeuf, Francois; Frossard, Nelly; Hachet-Haas, Muriel; Heunisch, Fabian; Reichetzeder, Christoph; Galzi, Jean-Luc; Perez-Castells, Javier; Canales-Mayordomo, Angeles; Jimenez-Barbero, Jesus; Gimenez-Gallego, Guillermo; Schneider, Marion; Shorter, James; Telenti, Amalio; Hocher, Berthold; Forssmann, Wolf-Georg; Bonig, Halvard; Kirchhoff, Frank; Muench, Jan 分享 收藏 Biologically Inactive Leptin and Early-Onset Extreme ObesityWabitsch, Martin; Funcke, Jan-Bernd; Lennerz, Belinda; Kuhnle-Krahl, Ursula; Lahr, Georgia; Debatin, Klaus-Michael; Vatter, Petra; Gierschik, Peter; Moepps, Barbara; Fischer-Posovszky, Pamela 分享 收藏 分享 收藏 分享 收藏 分享 收藏 A New Missense Mutation in the Leptin Gene Causes Mild Obesity and Hypogonadism without Affecting T Cell ResponsivenessFischer-Posovszky, Pamela; von Schnurbein, Julia; Moepps, Barbara; Lahr, Georgia; Strauss, Gudrun; Barth, Thomas F.; Kassubek, Jan; Muehleder, Hannes; Moeller, Peter; Debatin, Klaus-Michael; Gierschik, Peter; Wabitsch, Martin 分享 收藏 分享 收藏 
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