Andrea M. Hujer - Publications, H-index & Citations

Andrea M. Hujer

university of london school of pharmacy

61H指数

229论文数

1.2W被引数

收录论文 132

发表时间

Role of Ambler Position 104 in Defining Substrate Specificity in the KPC Family of β-Lactamases Ambler位置104在定义KPC家族β-内酰胺酶底物特异性中的作用

ACS Infectious Diseases

IF3.8

2026-04-01

OAAI

Gao, Lin; Marshall, Steven; Bethel, Christopher R.; Hujer, Andrea M.; Taracila, Magdalena A.; Hujer, Kristine M.; Haider, Shozeb; Bonomo, Robert A.

Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors 下一代β-内酰胺酶抑制剂的理性设计：结构与动力学基础

Journal of Medicinal Chemistry

IF6.8

2026-03-16

OAAI

Shuang Chen; Muchen Yu; Manming Xu; Sergio Decherchi; Magdalena A. Taracila; Andrea M. Hujer; Christopher R. Bethel; Robert A. Bonomo; Shozeb Haider

Cryptic Binding Pockets in PDC-3 β-Lactamase Modulate Resistance Profiles PDC-3 β-内酰胺酶中的隐藏结合口袋调节耐药谱

JACS Au

IF8.7

2026-02-20

OAAI

Shuang Chen; Fedaa Attana; Andrea M. Hujer; Christopher R. Bethel; Magdalena A. Taracila; Robert A. Bonomo; Shozeb Haider

A network analysis of carbapenem-resistant Klebsiella pneumoniae among healthcare facilities 医疗设施中耐碳青霉烯肺炎克雷伯菌的网络分析

Scientific Reports

IF3.9

2025-07-29

OAAI

Courtney L. Luterbach; Dana K. Pasquale; Heather I. Henderson; Eric Cober; Sandra S. Richter; Robert A. Salata; Robert C. Kalayjian; Richard R. Watkins; Andrea M. Hujer; Kristine M. Hujer; T. Nicholas Domitrovic; Yohei Doi; Keith S. Kaye; Scott Evans; Vance G. Fowler; Robert A. Bonomo; Barry Kreiswirth; Liang Chen; Cesar A. Arias; James Moody; David van Duin

Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter-derived cephalosporinase-33 (ADC-33), a class C β-lactamase present in carbapenem-resistant Acinetobacter baumannii (CRAb)由来源于鲍曼不动杆菌的头孢菌素酶-33（ADC-33）通过一种替代的水解机制赋予对氧亚氨基头孢菌素耐药性，ADC-33是一种存在于碳青霉烯耐药鲍曼不动杆菌（CRAb）中的C类β-内酰胺酶。

MBIO

IF4.7

2025-06-11

OAAI

Powers, Rachel A.; Wallar, Bradley J.; Jarvis, Hannah R.; Ziegler, Zoe X.; June, Cynthia M.; Bethel, Christopher R.; Hujer, Andrea M.; Taracila, Magdalena A.; Rudin, Susan D.; Hujer, Kristine M.; Prati, Fabio; Caselli, Emilia; Bonomo, Robert A.

A microbiological and structural analysis of the interplay between sulbactam/durlobactam and imipenem against penicillin-binding proteins (PBPs) of Acinetobacter spp.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2025-03-01

OAAI

Veeraraghavan, Balaji; Shin, Eunjeong; Bakthavatchalam, Yamuna Devi; Manesh, Abi; Dubey, Dilip; Tascini, Carlo; Taracila, Magdalena A.; Hujer, Andrea M.; Jacobs, Michael R.; Bonomo, Robert A.

β-Lactamase diversity in Acinetobacter baumannii 鲍曼不动杆菌 β-内酰胺酶多样性研究

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2025-02-10

OAAI

Mack, Andrew R.; Hujer, Andrea M.; Mojica, Maria F.; Taracila, Magdalena A.; Feldgarden, Michael; Haft, Daniel H.; Klimke, William; Prasad, Arjun B.; Bonomo, Robert A.

β-Lactamase diversity in Pseudomonas aeruginosa 铜绿假单胞菌的 β-内酰胺酶多样性

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2025-02-10

OAAI

Mack, Andrew R.; Hujer, Andrea M.; Mojica, Maria F.; Taracila, Magdalena A.; Feldgarden, Michael; Haft, Daniel H.; Klimke, William; Prasad, Arjun B.; Bonomo, Robert A.

Restoring cefepime activity against multidrug-resistant KPC-producing Klebsiella pneumoniae by combination with boronic acid inhibitors, MB076 and S02030

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2025-01-28

OAAI

Rojas, Laura J.; Nielsen, Travis B.; Pantapalangkoor, Paul; Taracila, Magdalena A.; Introvigne, Maria L.; Sharma, Rajnikant; Yeshwante, Shekhar; Mojica, Maria F.; Papp-Wallace, Krisztina M.; Hujer, Andrea M.; Prati, Fabio; Caselli, Emilia; Spellberg, Brad; Rather, Philip N.; Rao, Gauri G.; Bonomo, Robert A.

ARGONAUT-IV: susceptibility of carbapenemase-producing Klebsiella pneumoniae to the oral bicyclic boronate β-lactamase inhibitor ledaborbactam combined with ceftibuten

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-12-05

PREAI

Jacobs, Michael R.; Good, Caryn E.; Abdelhamed, Ayman M.; Mack, Andrew R.; Bethel, Christopher R.; Marshall, Steven H.; Hujer, Andrea M.; Hujer, Kristine M.; Patel, Robin; van Duin, David; Fowler, Vance G.; Rhoads, Daniel D.; Six, David A.; Moeck, Greg; Uehara, Tsuyoshi; Papp-Wallace, Krisztina M.; Bonomo, Robert A.

A molecular analysis of meropenem-vaborbactam non-susceptible KPC-producing Klebsiella pneumoniae 美罗培南-瓦硼巴坦非敏感KPC产生肺炎克雷伯菌的分子分析

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-10-08

PREAI

Yasmin, Mohamad; Marshall, Steven H.; Chen, Liang; Rhoads, Daniel D.; Jacobs, Michael R.; Rojas, Laura J.; Perez, Federico; Hujer, Andrea M.; Hujer, Kristine M.; van Duin, David; Fowler, Vance; Chambers, Henry F.; Kreiswirth, Barry N.; Bonomo, Robert A.

ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate β-lactamase inhibitor taniborbactam combined with cefepime

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-09-04

OAAI

Jacobs, Michael R.; Abdelhamed, Ayman M.; Good, Caryn E.; Mack, Andrew R.; Bethel, Christopher R.; Marshall, Steven; Hujer, Andrea M.; Hujer, Kristine M.; Patel, Robin; van Duin, David; Fowler, Vance G.; Rhoads, Daniel D.; Six, David A.; Moeck, Greg; Uehara, Tsuyoshi; Papp-Wallace, Krisztina M.; Bonomo, Robert A.

AMPLON: Amplifying DNA with Multiarm Priming and Looping Optimization of Nucleic Acid

ADVANCED MATERIALS

IF26.8

2024-05-06

OAAI

Doganay, Mert Tunca; Roman, Ethan; Hujer, Andrea M.; Bonomo, Robert A.; Deeks, Steven G.; Kuritzkes, Daniel R.; Draz, Mohamed S.

Insights into the activity of cefiderocol against PER-2 producing Enterobacterales

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-05-01

PREAI

Ruggiero, Melina; Briceno Munoz, Ivan; Gutkind, Gabriel; Hujer, Andrea M.; Bonomo, Robert A.; Power, Pablo

Deciphering the Coevolutionary Dynamics of L2 β-Lactamases via Deep Learning

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-04-30

OAAI

Zhu, Yu; Gu, Jing; Zhao, Zhuoran; Chan, A. W. Edith; Mojica, Maria F.; Hujer, Andrea M.; Bonomo, Robert A.; Haider, Shozeb

The Structural Role of N170 in Substrate-Assisted Deacylation in KPC-2 β-Lactamase

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-02-12

OAAI

Parwana, Diksha; Gu, Jing; Chen, Shuang; Bethel, Christopher R.; Marshall, Emma; Hujer, Andrea M.; Bonomo, Robert A.; Haider, Shozeb

The Real Crisis in Antimicrobial Resistance: Failure to Anticipate and Respond

CLINICAL INFECTIOUS DISEASES

IF7.3

2024-01-30

OAAI

Bonomo, Robert A.; Perez, Federico; Hujer, Andrea M.; Hujer, Kristine M.; Vila, Alejandro J.

Transcending the challenge of evolving resistance mechanisms in Pseudomonas aeruginosa through β-lactam-enhancer-mechanism-based cefepime/zidebactam

MBIO

IF4.7

2023-12-19

OAAI

Hujer, Andrea M.; Marshall, Steven H.; Mack, Andrew R.; Hujer, Kristine M.; Bakthavatchalam, Yamuna Devi; Umarkar, Kushal; Palwe, Snehal R.; Takalkar, Swapna; Joshi, Prashant R.; Shrivastava, Rahul; Periasamy, Hariharan; Bhagwat, Sachin S.; Patel, Mahesh V.; Veeraraghavan, Balaji; Bonomo, Robert A.

The directed evolution of NDM-1 NDM-1的定向进化

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2023-11-15

OAAI

Thomas, Caitlyn A.; Cheng, Zishuo; Bethel, Christopher R.; Hujer, Andrea M.; Sturgill, Aidan M.; Onuoha, Kelechi; Page, Richard C.; Bonomo, Robert A.; Crowder, Michael W.; Tamma, Pranita D.

Natural protein engineering in the Ω-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas-derived cephalosporinase

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2023-11-15

OAAI

Mack, Andrew R.; Kumar, Vijay; Taracila, Magdalena A.; Mojica, Maria F.; O'Shea, Margaret; Schinabeck, William; Silver, Galen; Hujer, Andrea M.; Papp-Wallace, Krisztina M.; Chen, Shuang; Haider, Shozeb; Caselli, Emilia; Prati, Fabio; van den Akker, Focco; Bonomo, Robert A.

研究方向