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S

Sarah Jaffe

Gilead Sciences
H指数:4
被引数:118
浏览量:0

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CBX250 Is a Novel Cathepsin G Peptide-HLA-Targeting T Cell Engager That Exhibits High Tumor Antigen and Potent Antileukemic In Vivo

CBX250是一种新型组织蛋白酶G肽-HLA靶向的T细胞结合剂，具有高肿瘤抗原性并在体内表现出强大的抗白血病活性。

BLOOD
IF23.1
2024-11-050
PRE
Lee, Benjamin H.; Paulus, Geraldine; Helble, Jennifer; Sankaran, Preethi; Rahman, Tanzila; O'Connor, Delainey; Bikowitz, Melissa; Jaffe, Sarah; Kulesha, Alona; Ban, Bhupal; Mak, Nga Sze Amanda; Princiotta, Michael; Shi, Chunhua; Yan, Jun; He, Hong; Feng, Ningping; Molldrem, Jeffrey J.; Heffernan, Timothy; Alatrash, Gheath; Wiederschain, Dmitri
Characterization of CBX-250, a first-in-class TCR-mimetic-based T-cell engager targeting a cathepsin G peptide-HLA complex for the treatment of myeloid leukemia
CANCER RESEARCH
IF16.6
2024-03-221
PRE
Paulus, Geraldine; Lee, Benjamin; Sankaran, Preethi; Rahman, Tanzila; Jimenez, Jessica; O'Connor, Delainey; Yue, Simon; Huang, Yu; Bikowitz, Melissa; Jaffe, Sarah; O'Malley, Shawn; Ban, Bhupal; Gabriely, Galina; Wang, Tao; Mak, Amanda; Princiotta, Michael; Shi, Chunhua; He, Helen; Feng, Ningping; Yan, Jun; Heffernan, Timothy; Alatrash, Gheath; Molldrem, Jeffrey; Wiederschain, Dmitri
Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-02-1014
OA
Umiker, Ben; Hashambhoy-Ramsay, Yasmin; Smith, Jeff; Rahman, Tanzila; Mueller, Amy; Davidson, Rachel; Meyer, Christina; Patankar, Gayatri; Alam, Mohammad Murshid; Jaffe, Sarah; Krukenberg, Kristin; Goodman, Allison; Spaulding, Vikki; Priess, Michelle; Dhaneshwar, Abha; Wong, Masie; Diiorio, Alexa; O'Malley, Kristin; McGrath, Lara; Willer, Margaret; Pepper, Lauren; Gostissa, Monica; Kis-Toth, Katalin; Wiederschain, Dmitri; Cohen, Heather; Shaffer, Donald R.
OVERLAPPING AND DISTINCT PATTERNS OF LILRB RECEPTORS SUPPORT COMPLEMENTARY TARGETING APPROACH IN CANCER
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-11-070
OA
Smith, Jeffrey; Mueller, Amy; Spaulding, Vikki; Priess, Michelle; Bala, Krithi; Dunn, Andrew; Jaffe, Sarah; Thompson, Morgan; Pignon, Jean-Christophe; Diiorio, Alexa; Cunha, Andre; Condurso, Heather; O'Malley, Kristin; Petrillo, Olivia; Venkatasubramanian, Prashanna Balaji; Young, Geneva; Meyer, Christina; Meehl, Michael; Kis-Toth, Katalin; Gostissa, Monica; Wiederschain, Dmitri; Umiker, Ben; Hashambhoy-Ramsay, Yasmin
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody
ONCOIMMUNOLOGY
IF6.3
2022-11-0415
OA
Weaver, Jessica D.; Stack, Edward C.; Bugge, Joshua A.; Hu, Changyun; McGrath, Lara; Mueller, Amy; Wong, Masie; Klebanov, Boris; Rahman, Tanzila; Kaufman, Rosemary; Fregeau, Christine; Spaulding, Vikki; Priess, Michelle; Legendre, Kristen; Jaffe, Sarah; Upadhyay, Dhruvkumar; Singh, Anirudh; Xu, Chang-Ai; Krukenberg, Kristin; Zhang, Yan; Ezzyat, Yassine; Axe, Dorothee Saddier; Kuhne, Michelle R.; Meehl, Michael A.; Shaffer, Donald R.; Weist, Brian M.; Wiederschain, Dmitri; Depis, Fabien; Gostissa, Monica

研究方向

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T
Tanzila Rahman
H 指数:5论文数:71被引数:151
D
Dmitri Wiederschain
H 指数:2论文数:63被引数:38
M
Michelle Priess
H 指数:2论文数:69被引数:84
G
Gheath Alatrash
H 指数:39论文数:638被引数:7,352
J
Jeffrey J. Molldrem
H 指数:56论文数:534被引数:1.2万
A
Amy Mueller
H 指数:15论文数:65被引数:1,793
M
Melissa J. Bikowitz
H 指数:7论文数:28被引数:282
B
Bhupal Ban
H 指数:7论文数:23被引数:212
T
Timothy P. Heffernan
H 指数:52论文数:459被引数:1.8万
C
Christina Meyer
H 指数:15论文数:82被引数:1,629