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收藏Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment
Burg, Shira; Shapiro, Shir; Peretz, Asher; Haimov, Elvira; Redko, Boris; Yeheskel, Adva; Simhaev, Luba; Engel, Hamutal; Raveh, Avi; Ben-Bassat, Ariel; Murninkas, Michael; Polak, Rotem; Haitin, Yoni; Etzion, Yoram; Attali, Bernard
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收藏A unique mechanism of inactivation gating of the Kv channel family member Kv7.1 and its modulation by PIP2 and calmodulin
Lipinsky, Maya; Tobelaim, William Sam; Peretz, Asher; Simhaev, Luba; Yeheskel, Adva; Yakubovich, Daniel; Lebel, Guy; Paas, Yoav; Hirsch, Joel A.; Attali, Bernard
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收藏Ca2+-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channelsCa2-钙调蛋白和PIP2在Kv7通道近端C末端的相互作用
Tobelaim, William S.; Dvir, Meidan; Lebel, Guy; Cui, Meng; Buki, Tal; Peretz, Asher; Marom, Milit; Haitin, Yoni; Logothetis, Diomedes E.; Hirsch, Joel A.; Attali, Bernard
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收藏SK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmias
Haron-Khun, Shiraz; Weisbrod, David; Bueno, Hanna; Yadin, Dor; Behar, Joachim; Peretz, Asher; Binah, Ofer; Hochhauser, Edith; Eldar, Michael; Yaniv, Yael; Arad, Michael; Attali, Bernard
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收藏Competition of calcified calmodulin N lobe and PIP2 to an LQT mutation site in Kv7.1 channel
Tobelaim, William Sam; Dvir, Meidan; Lebel, Guy; Cui, Meng; Buki, Tal; Peretz, Asher; Marom, Milit; Haitin, Yoni; Logothetis, Diomedes E.; Hirsch, Joel Alan; Attali, Bernard
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收藏Promiscuous gating modifiers target the voltage sensor of Kv7.2, TRPV1, and Hv1 cation channels
Kornilov, Polina; Peretz, Asher; Lee, Yoonji; Son, Karam; Lee, Jin Hee; Refaeli, Bosmat; Roz, Netta; Rehavi, Moshe; Choi, Sun; Attali, Bernard
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