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Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene 几乎2% 的西班牙乳腺癌家族与ATM基因的种系致病性突变有关。 Tavera-Tapia, A.; Perez-Cabornero, L.; Macias, J. A.; Ceballos, M. I.; Roncador, G.; de la Hoya, M.; Barroso, A.; Felipe-Ponce, V.; Serrano-Blanch, R.; Hinojo, C.; Miramar-Gallart, M. D.; Urioste, M.; Caldes, T.; Santillan-Garzon, S.; Benitez, J.; Osorio, A. 分享 收藏
Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect Vaclova, Tereza; Woods, Nicholas T.; Megias, Diego; Gomez-Lopez, Sergio; Setien, Fernando; Garcia Bueno, Jose Maria; Antonio Macias, Jose; Barroso, Alicia; Urioste, Miguel; Esteller, Manel; Monteiro, Alvaro N. A.; Benitez, Javier; Osorio, Ana 分享 收藏
Implications of the type of BRCA1 germline mutation in the treatment of patients with hereditary breast cancer Vaclova, Tereza; Woods, Nicholas T.; Setien, Fernando; Garcia Bueno, Jose Maria; Antonio Macias, Jose; Barroso, Alicia; Urioste, Miguel; Esteller, Manel; Monteiro, Alvaro N. A.; Benitez, Javier; Osorio, Ana 分享 收藏
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