Inna Astapova - Publications, H-index & Citations

Inna Astapova

Baylor College of Medicine

23H指数

48论文数

2.5K被引数

收录论文 26

发表时间

Genetics-nutrition interactions control diurnal enhancer-promoter dynamics and liver lipid metabolism 遗传-营养相互作用调控昼夜增强子-启动子动态和肝脏脂质代谢

Cell Metabolism

IF30.9

2025-08-25

PREAI

Dishu Zhou; Ying Chen; Panpan Liu; Kun Zhu; Juliet Holder-Haynes; S. Julie-Ann Lloyd; Cam Mong La; Inna I. Astapova; Seunghee Choa; Ying Xiong; Hosung Bae; Marlene Aguilar; Hongyuan Yang; Yu A. An; Zheng Sun; Mark A. Herman; Xia Gao; Liming Pei; Cholsoon Jang; Joshua D. Rabinowitz; Samer G. Mattar; Yongyou Zhang; Dongyin Guan

Integration of metabolomic and transcriptomic analyses reveals regulatory functions of the ChREBP transcription factor in energy metabolism 代谢组学和转录组学分析的整合揭示了ChREBP转录因子在能量代谢中的调控功能

CELL REPORTS

IF6.9

2025-02-01

OAAI

An, Jie; Astapova, Inna; Zhang, Guofang; Cangelosi, Andrew L.; Ilkayeva, Olga; Marchuk, Hannah; Muehlbauer, Michael J.; George, Tabitha; Brozinick, Joseph; Herman, Mark A.; Newgard, Christopher B.

Hepatic ChREBP-β Overexpression Enhances Peripheral Glucose and Lipid Homeostasis Independently of FGF21

DIABETES

IF7.5

2023-06-20

PREAI

Hannou, Sarah; Sargsyan, Ashot; Tong, Wenxin; Jie, An; Newgard, Christopher B.; Astapova, Inna; Herman, Mark A.

NCoR1 and SMRT Play Unique Roles in Thyroid Hormone Action In Vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Shimizu, Hiroaki; Astapova, Inna; Ye, Felix; Bilban, Martin; Cohen, Ronald N.; Hollenberg, Anthony N.

Thyroid Hormone Signaling In Vivo Requires a Balance between Coactivators and Corepressors

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Vella, Kristen R.; Ramadoss, Preeti; Costa-e-Sousa, Ricardo H.; Astapova, Inna; Ye, Felix D.; Holtz, Kaila A.; Harris, Jamie C.; Hollenberg, Anthony N.

HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

JCI INSIGHT

IF6.1

2023-01-10

OAAI

Sargsyan, Ashot; Doridot, Ludivine; Hannou, Sarah A.; Tong, Wenxin; Srinivasan, Harini; Ivison, Rachael; Monn, Ruby; Kou, Henry H.; Haldeman, Jonathan M.; Arlotto, Michelle; White, Phillip J.; Grimsrud, Paul A.; Astapova, Inna; Tsai, Linus T.; Herman, Mark A.

The intestine is a major contributor to circulating succinate in mice

FASEB JOURNAL

IF4.2

2022-09-15

OAAI

Tong, Wenxin; Hannou, Sarah A.; Wang, You; Astapova, Inna; Sargsyan, Ashot; Monn, Ruby; Thiriveedi, Venkataramana; Li, Diana; McCann, Jessica R.; Rawls, John F.; Roper, Jatin; Zhang, Guo-fang; Herman, Mark A.

A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice

NUTRIENTS

IF5

2021-10-18

OAAI

Doridot, Ludivine; Hannou, Sarah A.; Krawczyk, Sarah A.; Tong, Wenxin; Kim, Mi-Sung; McElroy, Gregory S.; Fowler, Alan J.; Astapova, Inna I.; Herman, Mark A.

HGFAC Is a ChREBP-Regulated Hepatokine That Enhances Glucose and Lipid Homeostasis

DIABETES

IF7.5

2021-06-01

PREAI

Sargsyan, Ashot; Doridot, Ludivine; Hannou, Sarah A.; Tong, Wenxin; Srinivasan, Harini; Ivison, Rachael; Monn, Ruby; Kou, Henry H.; Haldeman, Jonathan; Astapova, Inna; Tsai, Linus T.; Herman, Mark A.

The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition

DIABETES

IF7.5

2020-01-31

OAAI

Capozzi, Megan E.; Coch, Reilly W.; Koech, Jepchumba; Astapova, Inna I.; Wait, Jacob B.; Encisco, Sara E.; Douros, Jonathan D.; El, Kimberly; Finan, Brian; Sloop, Kyle W.; Herman, Mark A.; D'Alessio, David A.; Campbell, Jonathan E.

PPM1K Regulates β-Cell Proliferation, Insulin Content, and GSIS

DIABETES

IF7.5

2019-06-01

PREAI

Deleye, Yann; Herring, Jacob; Hess, Kavan H.; Leininger, Brennan R.; Hannou, Sarah A.; Astapova, Inna; Herman, Mark A.; Tessem, Jeffery S.; White, Phillip J.

Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha

THYROID

IF6.7

2019-05-01

OAAI

Freudenthal, Bernard; Shetty, Samiksha; Butterfield, Natalie C.; Logan, John G.; Han, Cho Rong; Zhu, Xuguang; Astapova, Inna; Hollenberg, Anthony N.; Cheng, Sheue-Yann; Bassett, J. H. Duncan; Williams, Graham R.

Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis 醛缩酶B介导的果糖代谢驱动结肠癌肝转移的代谢重编程

CELL METABOLISM

IF30.9

2018-06-01

198

OAAI

Bu, Pengcheng; Chen, Kai-Yuan; Xiang, Kun; Johnson, Christelle; Crown, Scott B.; Rakhilin, Nikolai; Ai, Yiwei; Wang, Lihua; Xi, Rui; Astapova, Inna; Han, Yan; Li, Jiahe; Barth, Bradley B.; Lu, Min; Gao, Ziyang; Mines, Robert; Zhang, Liwen; Herman, Mark; Hsu, David; Zhang, Guo-Fang; Shen, Xiling

Intestinal, but not hepatic, ChREBP is required for fructose tolerance

JCI INSIGHT

IF6.1

2017-12-21

OAAI

Kim, MiSung; Astapova, Inna I.; Flier, Sarah N.; Hannou, Sarah A.; Doridot, Ludivine; Sargsyan, Ashot; Kou, Henry H.; Fowler, Alan J.; Liang, Guosheng; Herman, Mark A.

NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-09-18

OAAI

Mendoza, Arturo; Astapova, Inna; Shimizu, Hiroaki; Gallop, Molly R.; Al-Sowaimel, Lujain; MacGowan, S. M. Dileas; Bergmann, Tim; Berg, Anders H.; Tenen, Danielle E.; Jacobs, Christopher; Lyubetskaya, Anna; Tsai, Linus; Hollenberg, Anthony N.

Role of co-regulators in metabolic and transcriptional actions of thyroid hormone

JOURNAL OF MOLECULAR ENDOCRINOLOGY

IF3.8

2016-04-01

OAAI

Astapova, Inna

Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-01-01

OAAI

Singh, Brijesh K.; Sinha, Rohit A.; Zhou, Jin; Tripathi, Madhulika; Ohba, Kenji; Wang, Mu-En; Astapova, Inna; Ghosh, Sujoy; Hollenberg, Anthony N.; Gauthier, Karine; Yen, Paul M.

Fibroblast Growth Factor 21 and Thyroid Hormone Show Mutual Regulatory Dependency but Have Independent Actions In Vivo

ENDOCRINOLOGY

IF3.3

2014-05-01

OAAI

Domouzoglou, Eleni M.; Fisher, Ffolliott Martin; Astapova, Inna; Fox, Elliott C.; Kharitonenkov, Alexei; Flier, Jeffrey S.; Hollenberg, Anthony N.; Maratos-Flier, Eleftheria

The Thyroid Axis Is Regulated by NCoR1 via Its Actions in the Pituitary

ENDOCRINOLOGY

IF3.3

2012-10-01

OAAI

Costa-e-Sousa, Ricardo H.; Astapova, Inna; Ye, Felix; Wondisford, Fredric E.; Hollenberg, Anthony N.

Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1)对甲状腺激素的抵抗力在体内由核受体抑制因子 (NCOR1) 调节。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-10-10

OAAI

Fozzatti, Laura; Lu, Changxue; Kim, Dong Wook; Park, Jeong Won; Astapova, Inna; Gavrilova, Oksana; Willingham, Mark C.; Hollenberg, Anthony N.; Cheng, Sheue-yann

研究方向