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Gary-Bobo, Magali; Elachouri, Ghizlane; Gallas, Jean Francois; Janiak, Philip; Marini, Pietro; Ravinet-Triflou, Christine; Chabbert, Michele; Cruccioli, Noel; Pfersdorff, Christian; Roque, Claude; Arnone, Michele; Croci, Tiziano; Soubrie, Philippe; Oury-Donat, Florence; Maffrand, Jean Pierre; Scatton, Bernard; Lacheretz, Frederic; Le Fur, Gerard; Herbert, Jean Marc; Bensaid, Mohammed .png)
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收藏Stimulation of the β3-adrenoceptor as a novel treatment strategy for anxiety and depressive disordersStemmelin, Jeanne; Cohen, Caroline; Terranova, Jean-Paul; Lopez-Grancha, Matilde; Pichat, Philippe; Bergis, Olivier; Decobert, Michel; Santucci, Vincent; Francon, Dominique; Alonso, Richard; Stahl, Stephen M.; Keane, Peter; Avenet, Patrick; Scatton, Bernard; le Fur, Gerard; Griebel, Guy 分享 收藏 分享 收藏 SSR180711, a novel selective α7 nicotinic receptor partial agonist:: (I) binding and functional profileBiton, Bruno; Bergis, Olivier E.; Galli, Frederic; Nedelec, Alain; Lochead, Alistair W.; Jegham, Samir; Godet, Danielle; Lanneau, Christophe; Santamaria, Raphael; Chesney, Francois; Leonardon, Jacques; Granger, Patrick; Debono, Marc W.; Bohme, Georg A.; Sgard, Frederic; Besnard, Francois; Graham, David; Coste, Annick; Oblin, Andre; Curet, Olivier; Vige, Xavier; Voltz, Corinne; Rouquier, Liliane; Souilhac, Josiane; Santucci, Vincent; Gueudet, Christiane; Francon, Dominique; Steinberg, Regis; Griebel, Guy; Oury-Donat, Florence; George, Pascal; Avenet, Patrick; Scatton, Bernard 分享 收藏 SSR180711, a novel selective α7 nicotinic receptor partial agonist:: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophreniaPichat, Philippe; Bergis, Olivier E.; Terranova, Jean-Paul; Urani, Alexandre; Duarte, Christine; Santucci, Vincent; Gueudet, Christiane; Voltz, Carole; Steinberg, Regis; Stemmelin, Jeanne; Oury-Donat, Florence; Avenet, Patrick; Griebel, Guy; Scatton, Bernard 分享 收藏 分享 收藏 Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-I SSR504734, a potential new type of antipsychoticDepoortère, R; Dargazanli, G; Estenne-Bouhtou, G; Coste, A; Lanneau, C; Desvignes, C; Poncelet, M; Heaulme, M; Santucci, V; Decobert, M; Cudennec, A; Voltz, C; Boulay, D; Terranova, JP; Stemmelin, J; Roger, P; Marabout, B; Sevrin, M; Vigé, X; Biton, B; Steinberg, R; Françon, D; Alonso, R; Avenet, P; Oury-Donat, F; Perrault, G; Griebel, G; George, P; Soubrié, P; Scatton, B 分享 收藏 SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist, alleviates disturbances of novelty discrimination in a social context in rats, a putative model of selective attention deficitTerranova, JP; Chabot, C; Barnouin, MC; Perrault, G; Depoortere, R; Griebel, G; Scatton, B 分享 收藏 分享 收藏 SL25.1131 [3(S),3a(S)-3-methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a new, reversible, and mixed inhibitor of monoamine oxidase-A and monoamine oxidase-B:: Biochemical and behavioral profileAubin, N; Barneoud, P; Carter, C; Caille, D; Sontag, N; Marc, C; Lolivier, J; Gardes, A; Perron, C; Le Kim, A; Charieras, T; Pandini, M; Burnier, P; Puech, F; Jegham, S; George, P; Scatton, B; Curet, O 分享 收藏 SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride):: A new selective and orally active oxytocin receptor antagonist for the prevention of preterm laborSerradeil-Le Gal, C; Valette, G; Foulon, L; Germain, G; Advenier, C; Naline, E; Bardou, M; Martinolle, JP; Pouzet, B; Raufaste, D; Garcia, C; Double-Cazanave, E; Pauly, M; Pascal, M; Barbier, A; Scatton, B; Maffrand, JP; Le Fur, G 分享 收藏 SSR591813, a novel selective and partial α4β2 nicotinic receptor agonist with potential as an aid to smoking cessationSSR591813，一种新型的选择性和部分 α4β2烟碱受体激动剂，具有戒烟的潜力Cohen, C; Bergis, OE; Galli, F; Lochead, AW; Jegham, S; Biton, B; Léonardon, J; Avenet, P; Sgard, F; Besnard, F; Graham, D; Coste, A; Oblin, A; Curet, O; Voltz, C; Gardes, A; Caille, D; Perrault, G; George, P; Soubrié, P; Scatton, B 分享 收藏 SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist.: I:: Neurochemical and electrophysiological profileSSR181507，多巴胺D2受体拮抗剂和5-HT1A受体激动剂。: I:: 神经化学和电生理特征Claustre, Y; De Peretti, D; Brun, P; Gueudet, C; Allouard, N; Alonso, R; Lourdelet, J; Oblin, A; Damoiseau, G; Françon, D; Suaud-Chagny, MF; Steinberg, R; Sevrin, M; Schoemaker, H; George, P; Soubrié, P; Scatton, B 分享 收藏 SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist.: II:: Behavioral profile predictive of an atypical antipsychotic activitySSR181507，多巴胺D2受体拮抗剂和5-HT1A受体激动剂。: II:: 预测非典型抗精神病药活性的行为特征Depoortere, R; Boulay, D; Perrault, G; Bergis, O; Decobert, M; Françon, D; Jung, M; Simiand, J; Soubrié, P; Scatton, B 分享 收藏 SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repairSSR180575 (7-氯-N，N，5-三甲基-4-氧代-3-苯基-3，5-二氢-4h-哒嗪并 [4，5-b]indole-1-acetamide)，一种外周苯二氮卓受体配体，促进神经元存活和修复Ferzaz, B; Brault, E; Bourliaud, G; Robert, JP; Poughon, G; Claustre, Y; Marguet, F; Liere, P; Schumacher, M; Nowicki, JP; Fournier, J; Marabout, B; Sevrin, M; George, P; Soubrie, P; Benavides, J; Scatton, B 分享 收藏 Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders非肽类血管加压素V1b受体拮抗剂SSR149415的抗焦虑和抗抑郁作用提示了一种治疗压力相关疾病的创新方法Griebel, G; Simiand, J; Gal, CSL; Wagnon, J; Pascal, M; Scatton, B; Maffrand, JP; Soubrié, P 分享 收藏 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A), a potent and selective corticotrophin-releasing factor1 receptor antagonist.: II.: Characterization in rodent models of stress-related disorders4-(2-氯-4-甲氧基-5-甲基苯基)-N-[(1s)-2-环丙基-1-(3-氟-4-甲基苯基) 乙基] 5-甲基-N-(2-丙炔基)-1，3-噻唑-2-胺盐酸盐 (SSR125543A)，一种有效的选择性促肾上腺皮质激素释放因子1受体拮抗剂。: II。: 在应激相关疾病的啮齿动物模型中的表征Griebel, G; Simiand, J; Steinberg, R; Jung, M; Gully, D; Roger, P; Geslin, M; Scatton, B; Maffrand, JP; Soubrié, P 分享 收藏 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A):: A potent and selective corticotrophin-releasing factor1 receptor antagonist.: I.: Biochemical and pharmacological characterization4-(2-氯-4-甲氧基-5-甲基苯基)-N-[(1s)-2-环丙基-1-(3-氟-4-甲基苯基) 乙基] 5-甲基-N-(2-丙炔基)-1，3-噻唑-2-胺盐酸盐 (SSR125543A):: 一种有效的选择性促肾上腺皮质激素释放因子1受体拮抗剂。: I.: 生化和药理学表征Gully, D; Geslin, M; Serva, L; Fontaine, E; Roger, P; Lair, C; Darre, V; Marcy, C; Rouby, PE; Simiand, J; Guitard, J; Gout, G; Steinberg, R; Rodier, D; Griebel, G; Soubrie, P; Pascal, M; Pruss, R; Scatton, B; Maffrand, JP; Le Fur, G 分享 收藏 Preclinical profile of befloxatone, a new reversible MAO-A inhibitorCuret, O; Damoiseau-Ovens, G; Sauvage, C; Sontag, N; Avenet, P; Depoortere, H; Caille, D; Bergis, O; Scatton, B 分享 收藏 分享 收藏 
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