Michael J. Root - Publications, H-index & Citations

Michael J. Root

swiss federal institutes of technology domain

20H指数

35论文数

1.4K被引数

收录论文 15

发表时间

Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env

PLOS PATHOGENS

IF4.9

2022-05-18

OAAI

Schapiro, Hannah M.; Khasnis, Mukta D.; Ahn, Koree; Karagiaridi, Alexandra; Hayden, Stephanie; Cilento, Maria E.; Root, Michael J.

Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-10-01

OAAI

Ahn, Koree W.; Root, Michael J.

Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer HIV-1 Env的受体激活导致gp41三聚体的不对称暴露

PLOS PATHOGENS

IF4.9

2016-12-19

OAAI

Khasnis, Mukta D.; Halkidis, Konstantine; Bhardwaj, Anshul; Root, Michael J.

Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus

PLOS PATHOGENS

IF4.9

2016-11-17

OAAI

Leslie, George J.; Wang, Jianbin; Richardson, Max W.; Haggarty, Beth S.; Hua, Kevin L.; Duong, Jennifer; Secreto, Anthony J.; Jordon, Andrea P. O.; Romano, Josephine; Kumar, Kritika E.; DeClercq, Joshua J.; Gregory, Philip D.; June, Carl H.; Root, Michael J.; Riley, James L.; Holmes, Michael C.; Hoxie, James A.

Site-Specific Polymer Attachment to HR2 Peptide Fusion Inhibitors against HIV-1 Decreases Binding Association Rates and Dissociation Rates Rather Than Binding Affinity

BIOCONJUGATE CHEMISTRY

IF3.9

2016-10-27

OAAI

Danial, Maarten; Stauffer, Angela N.; Wurm, Frederik R.; Root, Michael J.; Klok, Harm-Anton

Mechanism of Multivalent Nanoparticle Encounter with HIV-1 for Potency Enhancement of Peptide Triazole Virus Inactivation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-01-01

OAAI

Bastian, Arangassery Rosemary; Nangarlia, Aakansha; Bailey, Lauren D.; Holmes, Andrew; Sundaram, R. Venkat Kalyana; Ang, Charles; Moreira, Diogo R. M.; Freedman, Kevin; Duffy, Caitlin; Contarino, Mark; Abrams, Cameron; Root, Michael; Chaiken, Irwin

CD4 Binding Induces an Asymmetric Transition of HIV-1 Env from its Native Conformation into the Prehairpin Intermediate State

BIOPHYSICAL JOURNAL

IF3.1

2013-01-01

OAAI

Khasnis, Mukta D.; Halkidis, Konstantine; Bhardwaj, Anshul; Root, Michael

Polyvalent Side Chain Peptide-Synthetic Polymer Conjugates as HIV-1 Entry Inhibitors

BIOMACROMOLECULES

IF5.4

2012-04-27

OAAI

Danial, Maarten; Root, Michael J.; Klok, Harm-Anton

Nucleoporin Nup50 Stabilizes Closed Conformation of Armadillo repeat 10 in Importin α5

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-01-01

OAAI

Pumroy, Ruth A.; Nardozzi, Jonathan D.; Hart, Darren J.; Root, Michael J.; Cingolani, Gino

Design of a Potent D-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to Resistance

JOURNAL OF VIROLOGY

IF3.8

2010-11-01

169

OAAI

Welch, Brett D.; Francis, J. Nicholas; Redman, Joseph S.; Paul, Suparna; Weinstock, Matthew T.; Reeves, Jacqueline D.; Lie, Yolanda S.; Whitby, Frank G.; Eckert, Debra M.; Hill, Christopher P.; Root, Michael J.; Kay, Michael S.

Asymmetric Deactivation of HIV-1 gp41 following Fusion Inhibitor Binding

PLOS PATHOGENS

IF4.9

2009-11-26

OAAI

Kahle, Kristen M.; Steger, H. Kirby; Root, Michael J.

Interactions of HIV-1 Inhibitory Peptide T20 with the gp41 N-HR Coiled Coil

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2009-02-01

OAAI

Champagne, Kelly; Shishido, Akira; Root, Michael J.