未登录Optimization Efforts for Identification of Novel Highly Potent Keap1-Nrf2 Protein-Protein Interaction Inhibitors
Otake, Kazuki; Hara, Yoshinori; Ubukata, Minoru; Inoue, Masafumi; Nagahashi, Noboru; Motoda, Dai; Ogawa, Naoki; Hantani, Yoshiji; Hantani, Rie; Adachi, Tsuyoshi; Nomura, Akihiro; Yamaguchi, Keishi; Maekawa, Mariko; Mamada, Hideaki; Motomura, Takahisa; Sato, Motohide; Harada, Kazuhito .png)
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收藏Discovery and SAR of JTE-151: A Novel RORγ Inhibitor for Clinical DevelopmentMaeba, Takaki; Hirata, Kazuyuki; Kotoku, Masayuki; Seki, Noriyoshi; Maeda, Katsuya; Hirashima, Shintaro; Yamanaka, Hiroshi; Sakai, Takayuki; Obika, Shingo; Hori, Akimi; Hara, Yoshinori; Noji, Satoru; Suwa, Yoshihiro; Yokota, Masahiro; Fujioka, Shingo; Yamaguchi, Takayuki; Katsuda, Yoshiaki; Hata, Takahiro; Miyagawa, Naoki; Arita, Kojo; Nomura, Yukihiro; Taniguchi, Toshio; Asahina, Kota; Aratsu, Yusuke; Naka, Yuichi; Adachi, Tsuyoshi; Nomura, Akihiro; Akai, Shota; Oshida, Shin-ichi; Pai, Sudhakar; Crowe, Paul; Bradley, Erin; Steensma, Ruo; Tao, Haiyan; Fenn, Morgan; Babine, Robert; Li, Xiaolin; Thacher, Scott; Soeta, Takahiro; Ukaji, Yutaka; Shiozaki, Makoto 分享 收藏 Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitorsBessho, Yuki; Akaki, Tatsuo; Hara, Yoshinori; Yamakawa, Maki; Obika, Shingo; Mori, Genki; Ubukata, Minoru; Yasue, Katsutaka; Nakane, Yoshitomi; Terasako, Yasuo; Orita, Takuya; Doi, Satoki; Iwanaga, Tomoko; Fujishima, Ayumi; Adachi, Tsuyoshi; Ueno, Hiroshi; Motomura, Takahisa 分享 收藏 Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin DisordersNoji, Satoru; Hara, Yoshinori; Miura, Tomoya; Yamanaka, Hiroshi; Maeda, Katsuya; Hori, Akimi; Yamamoto, Hiroshi; Obika, Shingo; Inoue, Masafumi; Hase, Yasunori; Orita, Takuya; Doi, Satoki; Adachi, Tsuyoshi; Tanimoto, Atsuo; Oki, Chika; Kimoto, Yukari; Ogawa, Yoshihiro; Negoro, Tamotsu; Hashimoto, Hiromasa; Shiozaki, Makoto 分享 收藏 分享 收藏 分享 收藏 TOCILIZUMAB INDUCED CLINICAL REMISSION IN RHEUMATOID ARTHRITIS HAD MORE RESIDUAL DOPPLER SIGNALS IN COMPARISON WITH OTHER BIOLOGICSHara, Y.; Ishida, Y.; Yamaguchi, Y.; Yoshimine, Y.; Wibowo, T.; Manabe, Y.; Yaga, M.; Kawamoto, K.; Nakahara, H.; Higa, S.; Igarashi, T.; Maeda, K.; Ogata, A. 分享 收藏 Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitorsIkegashira, Kazutaka; Oka, Takahiro; Hirashima, Shintaro; Noji, Satoru; Yamanaka, Hiroshi; Hara, Yoshinori; Adachi, Tsuyoshi; Tsuruha, Jun-Ichiro; Doi, Satoki; Hase, Yasunori; Noguchi, Toru; Ando, Izuru; Ogura, Naoki; Ikeda, Satoru; Hashimoto, Hiromasa 分享 收藏 分享 收藏 
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