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Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor-binding domain (RBD) Kumru, Ozan S.; Bajoria, Sakshi; Kaur, Kawaljit; Hickey, John M.; Van Slyke, Greta; Doering, Jennifer; Berman, Katherine; Richardson, Charles; Lien, Hans; Kleanthous, Harry; Mantis, Nicholas J.; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
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Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants Bajoria, Sakshi; Kaur, Kawaljit; Kumru, Ozan S.; Van Slyke, Greta; Doering, Jennifer; Novak, Hayley; Rodriguez Aponte, Sergio A.; Dalvie, Neil C.; Naranjo, Christopher A.; Johnston, Ryan S.; Silverman, Judith Maxwell; Kleanthous, Harry; Love, J. Christopher; Mantis, Nicholas J.; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques HBsAg病毒样颗粒上显示的SARS-CoV-2受体结合域在猕猴中引起保护性免疫 Dalvie, Neil C.; Tostanoski, Lisa H.; Rodriguez-Aponte, Sergio A.; Kaur, Kawaljit; Bajoria, Sakshi; Kumru, Ozan S.; Martinot, Amanda J.; Chandrashekar, Abishek; McMahan, Katherine; Mercado, Noe B.; Yu, Jingyou; Chang, Aiquan; Giffin, Victoria M.; Nampanya, Felix; Patel, Shivani; Bowman, Lesley; Naranjo, Christopher A.; Yun, Dongsoo; Flinchbaugh, Zach; Pessaint, Laurent; Brown, Renita; Velasco, Jason; Teow, Elyse; Cook, Anthony; Andersen, Hanne; Lewis, Mark G.; Camp, Danielle L.; Silverman, Judith Maxwell; Nagar, Gaurav S.; Rao, Harish D.; Lothe, Rakesh R.; Chandrasekharan, Rahul; Rajurkar, Meghraj P.; Shaligram, Umesh S.; Kleanthous, Harry; Joshi, Sangeeta B.; Volkin, David B.; Biswas, Sumi; Love, J. Christopher; Barouch, Dan H. 分享 收藏
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice Dalvie, Neil C.; Rodriguez-Aponte, Sergio A.; Hartwell, Brittany L.; Tostanoski, Lisa H.; Biedermann, Andrew M.; Crowell, Laura E.; Kaur, Kawaljit; Kumru, Ozan S.; Carter, Lauren; Yu, Jingyou; Chang, Aiquan; McMahan, Katherine; Courant, Thomas; Lebas, Celia; Lemnios, Ashley A.; Rodrigues, Kristen A.; Silva, Murillo; Johnston, Ryan S.; Naranjo, Christopher A.; Tracey, Mary Kate; Brady, Joseph R.; Whittaker, Charles A.; Yun, Dongsoo; Brunette, Natalie; Wang, Jing Yang; Walkey, Carl; Fiala, Brooke; Kar, Swagata; Porto, Maciel; Lok, Megan; Andersen, Hanne; Lewis, Mark G.; Love, Kerry R.; Camp, Danielle L.; Silverman, Judith Maxwell; Kleanthous, Harry; Joshi, Sangeeta B.; Volkin, David B.; Dubois, Patrice M.; Collin, Nicolas; King, Neil P.; Barouch, Dan H.; Irvine, Darrell J.; Love, J. Christopher 分享 收藏
Dapsone-induced methaemoglobinaemia in leprosy: a close mimic of 'happy hypoxia' in the COVID-19 pandemic Tripathi, T.; Singh, A. R.; Kapoor, R.; Sinha, A.; Ghosh, S.; Kaur, K.; Pokhariya, D.; Maity, S.; Tapadar, A.; Chandra, A. 分享 收藏
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus Dalvie, Neil C.; Brady, Joseph R.; Crowell, Laura E.; Tracey, Mary Kate; Biedermann, Andrew M.; Kaur, Kawaljit; Hickey, John M.; Kristensen, D. Lee, II; Bonnyman, Alexandra D.; Rodriguez-Aponte, Sergio A.; Whittaker, Charles A.; Bok, Marina; Vega, Celina; Mukhopadhyay, Tarit K.; Joshi, Sangeeta B.; Volkin, David B.; Parreno, Viviana; Love, Kerry R.; Love, J. Christopher 分享 收藏
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Mechanism of Thimerosal-Induced Structural Destabilization of a Recombinant Rotavirus P[4] Protein Antigen Formulated as a Multi-Dose Vaccine Kaur, Kawaljit; Xiong, Jian; Sawant, Nishant; Agarwal, Sanjeev; Hickey, John M.; Holland, David A.; Mukhopadhyay, Tarit K.; Brady, Joseph R.; Dalvie, Neil C.; Tracey, Mary Kate; Love, Kerry R.; Love, J. Christopher; Weis, David D.; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens Sawant, Nishant; Kaur, Kawaljit; Holland, David A.; Hickey, John M.; Agarwal, Sanjeev; Brady, Joseph R.; Dalvie, Neil C.; Tracey, Mary Kate; Velez-Suberbie, M. Lourdes; Morris, Stephen A.; Jacob, Shaleem, I; Bracewell, Daniel G.; Mukhopadhyay, Tarit K.; Love, Kerry R.; Love, J. Christopher; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
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Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens Whitaker, Neal; Hickey, John M.; Kaur, Kawaljit; Xiong, Jian; Sawant, Nishant; Cupo, Albert; Lee, Wen-Hsin; Ozorowski, Gabriel; Medina-Ramirez, Max; Ward, Andrew B.; Sanders, Rogier W.; Moore, John P.; Joshi, Sangeeta B.; Volkin, David B.; Dey, Antu K. 分享 收藏
Analytical Comparability Assessments of 5 Recombinant CRM197 Proteins From Different Manufacturers and Expression Systems Hickey, John M.; Toprani, Vishal M.; Kaur, Kawaljit; Mishra, Ravi P. N.; Goel, Akshay; Oganesyan, Natalia; Lees, Andrew; Sitrin, Robert; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
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The Salmonella Type III Secretion System Inner Rod Protein PrgJ Is Partially Folded Zhong, Dalian; Lefebre, Matthew; Kaur, Kawaljit; McDowell, Melanie A.; Gdowski, Courtney; Jo, Sunhwan; Wang, Yu; Benedict, Stephen H.; Lea, Susan M.; Galan, Jorge E.; De Guzman, Roberto N. 分享 收藏