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Weston L. Daniel

Northwestern University
H指数:23
被引数:6,243
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A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation

TLR9激动剂球形核酸cavrotolimod在健康参与者中的首次人体1期研究: 免疫激活的证据

2022-12-1314
OAAI
SAFETY AND PRELIMINARY EFFICACY OF INTRATUMORAL CAVROTOLIMOD (AST-008), A SPHERICAL NUCLEIC ACID TLR9 AGONIST, IN COMBINATION WITH PEMBROLIZUMAB IN PATIENTS WITH ADVANCED SOLID TUMORS
2020-12-1010
PREAI
Phase 1b/2 study of an intratumoral TLR9 agonist spherical nucleic acid (AST-008) and pembrolizumab: Evidence of immune activation
2020-08-151
PRE
Targeting the IL-17 Receptor Using Liposomal Spherical Nucleic Acids as Topical Therapy for Psoriasis
2020-02-0147
OAAI
AST-008, a TLR9 agonist spherical nucleic acid, activated NK cells, T cells, and cytokines in healthy subjects in a Phase I clinical trial
2019-07-016
PRE
Topically-delivered gene suppressing nanocontruct targets IL-17RA for psoriasis
2018-05-010
OAAI
Topically Delivered Tumor Necrosis Factor-α-Targeted Gene Regulation for Psoriasis
2017-09-0135
OAAI
Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma
2013-10-30602
OA
Scanometric MicroRNA Array Profiling of Prostate Cancer Markers Using Spherical Nucleic Acid-Gold Nanoparticle Conjugates
2012-04-10159
OA
Multiplexed Nanoflares: mRNA Detection in Live Cells
2012-01-30299
OA
Scavenger Receptors Mediate Cellular Uptake of Polyvalent Oligonucleotide-Functionalized Gold Nanoparticles
2010-11-11391
OAAI
Polyvalent Oligonucleotide Gold Nanoparticle Conjugates as Delivery Vehicles for Platinum(IV) Warheads (vol 131, pg 14652, 2009)
2010-11-0510
OAAI
Tailoring DNA Structure To Increase Target Hybridization Kinetics on Surfaces (vol 132, 10638, 2010)
2010-10-218
OAAI
Tailoring DNA Structure To Increase Target Hybridization Kinetics on Surfaces
2010-07-1695
OAAI
Gold Nanoparticles for Biology and Medicine
2010-04-202.3K
OAAI
Colorimetric Cu2+ Detection Using DNA-Modified Gold-Nanoparticle Aggregates as Probes and Click Chemistry
SMALL
IF12.1
2010-03-08249
OAAI
Polyvalent Oligonucleotide Gold Nanoparticle Conjugates as Delivery Vehicles for Platinum(IV) Warheads (vol 131, pg 14652, 2009)
2010-02-095
OAAI
Bioluminescent nanosensors for protease detection based upon gold nanoparticle-luciferase conjugates
2010-01-01101
OA
Polyvalent Oligonucleotide Gold Nanoparticle Conjugates as Delivery Vehicles for Platinum(IV) Warheads

多价寡核苷酸金纳米粒子结合物作为铂 (IV) 弹头的递送载体

2009-09-24559
OAAI