Raquel C. de Melo-Minardi

universidade federal de minas gerais

20H指数

113论文数

1.4K被引数

收录论文 19

发表时间

Towards Fast Binding Affinity Scoring in Protein-Protein Complexes via Interatomic Contacts and Linear Regression 通过原子间接触和线性回归实现蛋白质-蛋白质复合物中快速结合亲和力评分

BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, X-MEETING 2025

IF0

2026-01-01

PREAI

Araujo Bastos, Ana Luisa; Lemos, Rafael Pereira; Mariano, Diego; Yamada, Camila A. O.; Pirovani, Milenna M.; Cardoso de Melo-Minardi, Raquel

Using Machine Learning and Graph-Based Signatures to Evaluate Normal and Decreased Function CYP2D6 Haplotypes 利用机器学习和基于图的特征评估正常和功能降低的CYP2D6单倍型

BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, X-MEETING 2025

IF0

2026-01-01

PREAI

Mariano, Diego; Puca, Maria Carolina; Salazar, Yanka E. A. R.; Lemos, Rafael Pereira; Maia, Giovana C. F.; dos Santos, Lucas Moraes; de Sousa, Tais Nobrega; Melo-Minardi, Raquel Cardosode

A hybrid evolutionary and structural method for AI-guided peptide inhibitor design using AlphaFold and Rosetta 一种结合进化与结构方法、利用AlphaFold和Rosetta的AI引导肽抑制剂设计方法

Scientific Reports

IF3.9

2025-11-29

OAAI

Frederico Chaves Carvalho; Diego Mariano; Luana Bastos; Ana Paula de Abreu; Rafael Pereira Lemos; Sheila Cruz Araújo; Lucas Moraes dos Santos; Raquel Cardoso de Melo-Minardi

COCαDA - a fast and scalable algorithm for interatomic contact detection in proteins using Cα distance matrices COCαDA - 一种用于蛋白质中原子间接触检测的快速且可扩展的Cα距离矩阵算法

Frontiers in Bioinformatics

IF3.9

2025-09-01

OAAI

Rafael Pereira Lemos; Diego Mariano; Sabrina De Azevedo Silveira; Raquel C. de Melo-Minardi

In vitro enzymatic and cell culture assays for SARS-CoV-2 main protease interaction with ambenonium

SCIENTIFIC REPORTS

IF3.9

2025-03-27

OAAI

de Souza, Juliana angelo; Gomes, Isabela de Souza; Fernandes, Luciana de Souza; Andrade, Luis Adan Flores; de Souza, Luciana angelo; Paiva, Vinicius de Almeida; Araujo, Sheila Cruz; de Lima, Leonardo Henrique Franca; Dias, Roberto Sousa; de Melo-Minardi, Raquel Cardoso; da Fonseca, Flavio Guimaraes; de Paula, Sergio Oliveira; Silveira, Sabrina de Azevedo

Deep learning for discriminating non-trivial conformational changes in molecular dynamics simulations of SARS-CoV-2 spike-ACE2 用于区分SARS-CoV-2 spike-ACE2分子动力学模拟中非平凡构象变化的深度学习

SCIENTIFIC REPORTS

IF3.9

2024-09-30

OAAI

dos Santos, Lucas Moraes; de Mendonca, Jose Gutembergue; Lobo, Yan Jeronimo Gomes; de Lima, Leonardo Henrique Franca; Rocha, Gerd Bruno; de Melo-Minardi, Raquel C.

Interaction of DisBa01 peptide from Bothrops alternatus venom with BRAF melanoma receptors: Modeling and molecular docking

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-08-01

PREAI

Bialves, Tatiane Senna; Bastos, Luana Luiza; Parra, John Alexanders Amaya; Moyses, Mauricio Nogueira; Marques, Edleusa; Pimenta, Adriano Monteiro de Castro; Quintela, Fernando Marques; Mariano, Diego Cesar Batista; Carvalho, Frederico Chaves; de Melo-Minardi, Raquel C.; Boyle, Robert Tew

An Approach for Engineering Peptides for Competitive Inhibition of the SARS-COV-2 Spike Protein

MOLECULES

IF4.6

2024-04-01

OAAI

de Abreu, Ana Paula; Carvalho, Frederico Chaves; Mariano, Diego; Bastos, Luana Luiza; Pereira Silva, Juliana Rodrigues; de Oliveira, Leandro Morais; de Melo-Minardi, Raquel C.; Sabino, Adriano de Paula

Elucidating the molecular mechanisms of essential oils' insecticidal action using a novel cheminformatics protocol

SCIENTIFIC REPORTS

IF3.9

2023-03-21

OAAI

Correa, Eduardo Jose Azevedo; Carvalho, Frederico Chaves; Oliveira, Julia Assuncao de Castro; Bertolucci, Suzan Kelly Vilela; Scotti, Marcus Tullius; Silveira, Carlos Henrique; Guedes, Fabiana Costa; Melo, Julio Onesio Ferreira; de Melo-Minardi, Raquel Cardoso; de Lima, Leonardo Henrique Franca

Thermostabilizing mechanisms of canonical single amino acid substitutions at a GH1 β-glucosidase probed by multiple MD and computational approaches

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2022-10-10

PREAI

Oliveira Rocha, Rafael Eduardo; Batista Mariano, Diego Cesar; Almeida, Tiago Silva; CorreaCosta, Leon Sulfierry; Camargo Fischer, Pedro Henrique; Santos, Lucianna Helene; Caffarena, Ernesto Raul; da Silveira, Carlos Henrique; Lamp, Leonida M.; Fernandez-Quintero, Monica Lisa; Liedl, Klaus Roman; De Melo-Minardi, Raquel Cardoso; Franca de Lima, Leonardo Henrique

Prioritizing Virtual Screening with Interpretable Interaction Fingerprints

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2022-09-14

OAAI

Fassio, Alexandre, V; Shub, Laura; Ponzoni, Luca; McKinley, Jessica; O'Meara, Matthew J.; Ferreira, Rafaela S.; Keiser, Michael J.; de Melo Minardi, Raquel C.

Protein structural bioinformatics: An overview 蛋白质结构生物信息学: 综述

COMPUTERS IN BIOLOGY AND MEDICINE

IF6.3

2022-08-01

PREAI

Paiva, Vinicius de Almeida; Gomes, Isabela de Souza; Monteiro, Cleiton Rodrigues; Mendonca, Murillo Ventura; Martins, Pedro Magalhaes; Santana, Charles Abreu; Goncalves-Almeida, Valdete; Izidoro, Sandro Carvalho; de Melo-Minardi, Raquel Cardoso; Silveira, Sabrina de Azevedo

GRaSP-web: a machine learning strategy to predict binding sites based on residue neighborhood graphs Grasb-web: 一种基于残基邻域图预测结合位点的机器学习策略

NUCLEIC ACIDS RESEARCH

IF13.1

2022-05-07

OAAI

Santana, Charles A.; Izidoro, Sandro C.; De Melo-Minardi, Raquel C.; Tyzack, Jonathan D.; Ribeiro, Antonio J. M.; Pires, Douglas E., V; Thornton, Janet M.; Silveira, Sabrina de A.

nAPOLI: A Graph-Based Strategy to Detect and Visualize Conserved Protein-Ligand Interactions in Large-Scale

IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS

IF3.4

2020-07-01

PREAI

Fassio, Alexandre V.; Santos, Lucianna H.; Silveira, Sabrina A.; Ferreira, Rafaela S.; de Melo-Minardi, Raquel C.

Molecular Dynamics Gives New Insights into the Glucose Tolerance and Inhibition Mechanisms on β-Glucosidases

MOLECULES

IF4.6

2019-09-04

OAAI

Correa Costa, Leon Sulfierry; Batista Mariano, Diego Cesar; Oliveira Rocha, Rafael Eduardo; Kraml, Johannes; da Silveira, Carlos Henrique; Liedl, Klaus Roman; de Melo-Minardi, Raquel Cardoso; Franca de Lima, Leonardo Henrique

Revealing the hidden functional diversity of an enzyme family

NATURE CHEMICAL BIOLOGY

IF13.7

2013-11-17

PREAI

Bastard, Karine; Smith, Adam Alexander Thil; Vergne-Vaxelaire, Carine; Perret, Alain; Zaparucha, Anne; De Melo-Minardi, Raquel; Mariage, Aline; Boutard, Magali; Debard, Adrien; Lechaplais, Christophe; Pelle, Christine; Pellouin, Virginie; Perchat, Nadia; Petit, Jean-Louis; Kreimeyer, Annett; Medigue, Claudine; Weissenbach, Jean; Artiguenave, Franois; De Berardinis, Veronique; Vallenet, David; Salanoubat, Marcel

Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns

BMC GENOMICS

IF3.7

2011-12-22

OAAI

Pires, Douglas E. V.; de Melo-Minardi, Raquel C.; dos Santos, Marcos A.; da Silveira, Carlos H.; Santoro, Marcelo M.; Meira, Wagner, Jr.

3-Keto-5-aminohexanoate Cleavage Enzyme A COMMON FOLD FOR AN UNCOMMON CLAISEN-TYPE CONDENSATION

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-08-01

OAAI

Bellinzoni, Marco; Bastard, Karine; Perret, Alain; Zaparucha, Anne; Perchat, Nadia; Vergne, Carine; Wagner, Tristan; de Melo-Minardi, Raquel C.; Artiguenave, Francois; Cohen, Georges N.; Weissenbach, Jean; Salanoubat, Marcel; Alzari, Pedro M.

Protein cutoff scanning: A comparative analysis of cutoff dependent and cutoff free methods for prospecting contacts in proteins

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2008-08-14

OAAI

da Silveira, Carlos H.; Pires, Douglas E. V.; Minardi, Raquel C.; Ribeiro, Cristina; Veloso, Caio J. M.; Lopes, Julio C. D.; Meira, Wagner, Jr.; Neshich, Goran; Ramos, Carlos H. I.; Habesch, Raul; Santoro, Marcelo M.

研究方向