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Discovery and development of novel CNS-penetrating PARP1-selective inhibitors 新型中枢神经系统穿透性PARP1选择性抑制剂的发现与开发 Bacha, Jeffrey; Truong, Sarah; Ban, Fuqiang; Smith, Jason; Pandey, Mohit; Manskaia, Ekaterina; Zhai, Beibei; Ramos, Louise; Marzban, Mona; Ghaidi, Fariba; Adomat, Hans; Singh, Kally; Chen, Xiaoqi; Brown, Dennis; Langlands, John; Collins, Colin; Cherkasov, Artem; Daugaard, Mads 分享 收藏
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UTILIZING DEEP DOCKING AND ARTIFICIAL INTELLIGENCE FOR THE DISCOVERY OF NOVEL PARP1-SELECTIVE INHIBITORS FOR USE AGAINST BRAIN TUMORS Truong, Sarah; Ban, Fuqiang; Smith, Jason; Zhai, Beibei; Ramos, Louise; Marzban, Mona; Ghaidi, Fariba; Adomat, Hans; Chen, Xiaoqi; Langlands, John; Brown, Dennis; Bacha, Jeffrey; Collins, Colin; Cherkasov, Artem; Daugaard, Mads 分享 收藏
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Pharmacological synthetic lethality by co-inhibition of PARP and HDAC enzymes Truong, Sarah; Ramos, Louise; Zhai, Beibei; Ghaidi, Fariba; Marzban, Mona; Adomat, Hans; Chen, Xiaoqi; Langlands, John; Brown, Dennis; Bacha, Jeffrey; Collins, Colin; Sorensen, Poul H.; Shen, Wang; Daugaard, Mads 分享 收藏
Small-molecule bifunctional inhibitors of PARP1/2 and HDAC enzymes Truong, Sarah; Ramos, Louise; Zhai, Beibei; Joshi, Jay; Ghaidi, Fariba; Marzban, Mona; Adomat, Hans; Chen, Charles; Langlands, John; Brown, Dennis; Bache, Jeffrey; Collins, Colin; Sorensen, Poul; Shen, Wang; Daugaard, Mads 分享 收藏
Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells Yenki, Parvin; Bhasin, Satyam; Liu, Liang; Nabavi, Noushin; Cheng, Chi Wing; Tam, Kevin J.; Peacock, James W.; Adomat, Hans H.; Tombe, Tabitha; Fazli, Ladan; Ivanova, Larissa; Dusek, Christopher; Khosravi, Shahram; Guns, Emma S. Tomlinson; Wang, Yuzhuo; Buttyan, Ralph; Gleave, Martin E.; Ong, Christopher J. 分享 收藏
Chaperone-mediated autophagy promotes PCa survival during ARPI through selective proteome remodeling Nikesitch, Nicholas; Beraldi, Eliana; Zhang, Fan; Adomat, Hans; Bell, Robert; Suzuki, Kotaro; Fazli, Ladan; Hy Kung, Sonia; Wells, Christopher; Pinette, Nicholas; Saxena, Neetu; Wang, Yuzhuo; Gleave, Martin 分享 收藏
Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer PTUPB对AKR1C3和雄激素受体轴的新型抑制作用协同恩杂鲁胺治疗晚期前列腺癌 Yang, Joy C.; Xu, Pengfei; Ning, Shu; Wasielewski, Logan J.; Adomat, Hans; Hwang, Sung Hee; Morisseau, Christophe; Gleave, Martin; Corey, Eva; Gao, Allen C.; Lara, Primo N., Jr.; Evans, Christopher P.; Hammock, Bruce D.; Liu, Chengfei 分享 收藏
Indwelling stents cause obstruction and induce ureteral injury and fibrosis in a porcine model Scotland, Kymora B.; Almutairi, Khaled; Park, Elliya; Wang, Lu; Kung, Sonia H. Y.; Haegert, Anne; Adomat, Hans; Bell, Robert; LeBihan, Stephane; Chew, Ben H.; Lange, Dirk 分享 收藏
Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer Al-Nakouzi, Nader; Wang, Chris Kedong; Oo, Htoo Zarni; Nelepcu, Irina; Lallous, Nada; Spliid, Charlotte B.; Khazamipour, Nastaran; Lo, Joey; Truong, Sarah; Collins, Colin; Hui, Desmond; Esfandnia, Shaghayegh; Adomat, Hans; Clausen, Thomas Mandel; Gustavsson, Tobias; Choudhary, Swati; Dagil, Robert; Corey, Eva; Wang, Yuzhuo; Chauchereau, Anne; Fazli, Ladan; Esko, Jeffrey D.; Salanti, Ali; Nelson, Peter S.; Gleave, Martin E.; Daugaard, Mads 分享 收藏
Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells Wang, Chris Kedong; Nelepcu, Irina; Hui, Desmond; Oo, Htoo Zarni; Truong, Sarah; Zhao, Sarah; Tahiry, Zakir; Esfandnia, Shaghayegh; Ghaidi, Fariba; Adomat, Hans; Dagil, Robert; Gustavsson, Tobias; Choudhary, Swati; Salanti, Ali; Sorensen, Poul H.; Al Nakouzi, Nader; Daugaard, Mads 分享 收藏
A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke (vol 8, 611367, 2021) Eyford, Brett A.; Singh, Chaahat S. B.; Abraham, Thomas; Munro, Lonna; Choi, Kyung Bok; Hill, Tracy; Hildebrandt, Rhonda; Welch, Ian; Vitalis, Timothy Z.; Gabathuler, Reinhard; Gordon, Jacob A.; Adomat, Hans; Guns, Emma S. T.; Lu, Chieh-Ju; Pfeifer, Cheryl G.; Tian, Mei Mei; Jefferies, Wilfred A. 分享 收藏
A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke Eyford, Brett A.; Singh, Chaahat S. B.; Abraham, Thomas; Munro, Lonna; Choi, Kyung Bok; Hill, Tracy; Hildebrandt, Rhonda; Welch, Ian; Vitalis, Timothy Z.; Gabathuler, Reinhard; Gordon, Jacob A.; Adomat, Hans; Guns, Emma S. T.; Lu, Chieh-Ju; Pfeifer, Cheryl G.; Tian, Mei Mei; Jefferies, Wilfred A. 分享 收藏
Androgen receptor (AR) antagonism triggers acute succinate-mediated adaptive responses to reactivate AR signaling Saxena, Neetu; Beraldi, Eliana; Fazli, Ladan; Somasekharan, Syam Prakash; Adomat, Hans; Zhang, Fan; Molokwu, Chidi; Gleave, Anna; Nappi, Lucia; Nguyen, Kimberly; Brar, Pavn; Nikesitch, Nicholas; Wang, Yuzhuo; Collins, Colin; Sorensen, Poul H.; Gleave, Martin 分享 收藏
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G3BP1-linked mRNA partitioning supports selective protein synthesis in response to oxidative stress Somasekharan, Syam Prakash; Zhang, Fan; Saxena, Neetu; Huang, Jia Ni; Kuo, I-Chih; Low, Caitlin; Bell, Robert; Adomat, Hans; Stoynov, Nikolay; Foster, Leonard; Gleave, Martin; Sorensen, Poul H. 分享 收藏
A polymeric paste-drug formulation for intratumoral treatment of prostate cancer Kesch, Claudia; Schmitt, Veronika; Bidnur, Samir; Thi, Marisa; Beraldi, Eliana; Moskalev, Igor; Yago, Virginia; Bowden, Mary; Adomat, Hans; Fazil, Ladan; Jackson, John K.; Gleave, Martin E. 分享 收藏
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