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Tumor microenvironment and breast cancer survival: combined effects of breast fat, M2 macrophages and hyaluronan create a dismal prognosis 肿瘤微环境与乳腺癌生存: 乳腺脂肪、M2巨噬细胞和透明质酸的联合作用造成了令人沮丧的预后 Tiainen, Satu; Masarwah, Amro; Oikari, Sanna; Rilla, Kirsi; Hamalainen, Kirsi; Sudah, Mazen; Sutela, Anna; Vanninen, Ritva; Ikonen, Juho; Tammi, Raija; Tammi, Markku; Auvinen, Paivi 分享 收藏
Extracellular ATP activates hyaluronan synthase 2 (HAS2) in epidermal keratinocytes via P2Y2, Ca2+ signaling, and MAPK pathways Rauhala, Leena; Jokela, Tiina; Karna, Riikka; Bart, Genevieve; Takabe, Piia; Oikari, Sanna; Tammi, Markku I.; Pasonen-Seppanen, Sanna; Tammi, Raija H. 分享 收藏
Hyaluronan metabolism enhanced during epidermal differentiation is suppressed by vitamin C Hamalainen, L.; Karkkainen, E.; Takabe, P.; Rauhala, L.; Bart, G.; Karna, R.; Pasonen-Seppanen, S.; Oikari, S.; Tammi, M. I.; Tammi, R. H. 分享 收藏
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High extent of O-GlcNAcylation in breast cancer cells correlates with the levels of HAS enzymes, accumulation of hyaluronan, and poor outcome 乳腺癌细胞中o-glcnacylation的高程度与hs酶的水平，透明质酸的积累和不良结果相关 Tiainen, Satu; Oikari, Sanna; Tammi, Markku; Rilla, Kirsi; Hamalainen, Kirsi; Tammi, Raija; Kosma, Veli-Matti; Auvinen, Paivi 分享 收藏
UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression Deen, Ashik Jawahar; Arasu, Uma Thanigai; Pasonen-Seppanen, Sanna; Hassinen, Antti; Takabe, Piia; Wojciechowski, Sara; Karna, Riikka; Rilla, Kirsi; Kellokumpu, Sakari; Tammi, Raija; Tammi, Markku; Oikari, Sanna 分享 收藏
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The reciprocal association between mammographic breast density, hyaluronan synthesis and patient outcome Masarwah, Amro; Tammi, Markku; Sudah, Mazen; Sutela, Anna; Oikari, Sanna; Kosma, Veli-Matti; Tammi, Raija; Vanninen, Ritva; Auvinen, Paivi 分享 收藏
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Interleukin-1-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesive Hyaluronan Coats Jokela, Tiina; Oikari, Sanna; Takabe, Piia; Rilla, Kirsi; Karna, Riikka; Tammi, Markku; Tammi, Raija 分享 收藏
Fluorescence Resonance Energy Transfer (FRET) and Proximity Ligation Assays Reveal Functionally Relevant Homo-and Heteromeric Complexes among Hyaluronan Synthases HAS1, HAS2, and HAS3 Bart, Genevieve; Vico, Nuria Ortega; Hassinen, Antti; Pujol, Francois M.; Deen, Ashik Jawahar; Ruusala, Aino; Tammi, Raija H.; Squire, Anthony; Heldin, Paraskevi; Kellokumpu, Sakari; Tammi, Markku I. 分享 收藏
High numbers of macrophages, especially M2-like (CD163-positive), correlate with hyaluronan accumulation and poor outcome in breast cancer Tiainen, Satu; Tumelius, Ritva; Rilla, Kirsi; Hamalainen, Kirsi; Tammi, Markku; Tammi, Raija; Kosma, Veli-Matti; Oikari, Sanna; Auvinen, Paivi 分享 收藏
rClca2 is associated with epidermal differentiation and is strongly downregulated by ultraviolet radiation Bart, G.; Hamalainen, L.; Rauhala, L.; Salonen, P.; Kokkonen, M.; Dunlop, T. W.; Pehkonen, P.; Kumlin, T.; Tammi, M. I.; Pasonen-Seppanen, S.; Tammi, R. H. 分享 收藏
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Rab10-mediated Endocytosis of the Hyaluronan Synthase HAS3 Regulates Hyaluronan Synthesis and Cell Adhesion to Collagen Deen, Ashik Jawahar; Rilla, Kirsi; Oikari, Sanna; Karna, Riikka; Bart, Genevieve; Hayrinen, Jukka; Bathina, Avinash Rahul; Ropponen, Antti; Makkonen, Katri; Tammi, Raija H.; Tammi, Markku I. 分享 收藏
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Hyaluronan synthases (HAS1-3) in stromal and malignant cells correlate with breast cancer grade and predict patient survival Auvinen, Paivi; Rilla, Kirsi; Tumelius, Ritva; Tammi, Markku; Sironen, Reijo; Soini, Ylermi; Kosma, Veli-Matti; Mannermaa, Arto; Viikari, Jukka; Tammi, Raija 分享 收藏
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