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Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive Fleischmann, Zoe; 'Heureux, Auden Cote-L; Franco, Melissa; Oreshkov, Sergey; Annis, Sofia; Khrapko, Mark; Aidlen, Dylan; Popadin, Konstantin; Woods, Dori C.; Tilly, Jonathan L.; Khrapko, Konstantin 分享 收藏
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Dynamics of the most common pathogenic mtDNA variant m.3243A > G demonstrate frequency-dependency in blood and positive selection in the germline Franco, Melissa; Pickett, Sarah J.; Fleischmann, Zoe; Khrapko, Mark; Cote-L'Heureux, Auden; Aidlen, Dylan; Stein, David; Markuzon, Natasha; Popadin, Konstantin; Braverman, Maxim; Woods, Dori C.; Tilly, Jonathan L.; Turnbull, Doug M.; Khrapko, Konstantin 分享 收藏
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Workflow Optimization for Identification of Female Germline or Oogonial Stem Cells in Human Ovarian Cortex Using Single-Cell RNA Sequence Analysis Alberico, Hannah; Fleischmann, Zoe; Bobbitt, Tyler; Takai, Yasushi; Ishihara, Osamu; Seki, Hiroyuki; Anderson, Richard A.; Telfer, Evelyn E.; Woods, Dori C.; Tilly, Jonathan L. 分享 收藏
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A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics MacDonald, Julie A.; Bothun, Alisha M.; Annis, Sofia N.; Sheehan, Hannah; Ray, Somak; Gao, Yuanwei; Ivanov, Alexander R.; Khrapko, Konstantin; Tilly, Jonathan L.; Woods, Dori C. 分享 收藏
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Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis Safdar, Adeel; Annis, Sofia; Kraytsberg, Yevgenya; Laverack, Chloe; Saleem, Ayesha; Popadin, Konstantin; Woods, Dori C.; Tilly, Jonathan L.; Khrapko, Konstantin 分享 收藏
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Loss of CABLES1, a cyclin-dependent kinase-interacting protein that inhibits cell cycle progression, results in germline expansion at the expense of oocyte quality in adult female mice Lee, Ho-Joon; Sakamoto, Hideo; Luo, Hongwei; Skaznik-Wikiel, Malgorzata E.; Friel, Anne M.; Niikura, Teruko; Tilly, Jacqueline C.; Niikura, Yuichi; Klein, Rachael; Styer, Aaron K.; Zukerberg, Lawrence R.; Tilly, Jonathan L.; Rueda, Bo. R. 分享 收藏
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