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Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders Ruf, Sven; Rajagopal, Sridharan; Kadnur, Sanjay Venkatachalapathi; Hallur, Mahanandeesha S.; Rani, Shilpa; Kristam, Rajendra; Swaminathan, Srinivasan; Zope, Bharat Ravindra; Gondrala, Pavan Kumar; Swamy, Indu; Putta, V. P. Rama Kishore; Kandan, Saravanan; Zech, Gernot; Schreuder, Herman; Rudolph, Christine; Elvert, Ralf; Czech, Joerg; Birudukota, Swarnakumari; Siddiqui, M. Amir; Anand, Niranjan Naranapura; Mane, Vishal Subhash; Dittakavi, Sreekanth; Suresh, Juluri; Gosu, Ramachandraiah; Ramesh, Mullangi; Yura, Takeshi; Dhakshinamoorthy, Saravanakumar; Kannt, Aimo 分享 收藏
The PROTACtable genome 可替代的基因组 Schneider, Melanie; Radoux, Chris J.; Hercules, Andrew; Ochoa, David; Dunham, Ian; Zalmas, Lykourgos-Panagiotis; Hessler, Gerhard; Ruf, Sven; Shanmugasundaram, Veerabahu; Hann, Michael M.; Thomas, Pam J.; Queisser, Markus A.; Benowitz, Andrew B.; Brown, Kris; Leach, Andrew R. 分享 收藏
Novel Inhibitors of Nicotinamide-N-Methyltransferase for the Treatment of Metabolic Disorders Kannt, Aimo; Rajagopal, Sridharan; Hallur, Mahanandeesha S.; Swamy, Indu; Kristam, Rajendra; Dhakshinamoorthy, Saravanakumar; Czech, Joerg; Zech, Gernot; Schreuder, Herman; Ruf, Sven 分享 收藏
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Photoredox-Mediated Hydrogen Isotope Exchange Reactions of Amino-Acids, Peptides, and Peptide-Derived Drugs Legros, Fabien; Fernandez-Rodriguez, Patricia; Mishra, Anurag; Weck, Remo; Bauer, Armin; Sandvoss, Martin; Ruf, Sven; Mendez, Maria; Mora-Rado, Helena; Rackelmann, Nils; Poeverlein, Christoph; Derdau, Volker 分享 收藏
Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice Hohl, Mathias; Mayr, Manuel; Lang, Lisa; Nickel, Alexander G.; Barallobre-Barreiro, Javier; Yin, Xiaoke; Speer, Thimoteus; Selejan, Simina-Ramona; Goettsch, Claudia; Erb, Katharina; Fecher-Trost, Claudia; Reil, Jan-Christian; Linz, Benedikt; Ruf, Sven; Huebschle, Thomas; Maack, Christoph; Boehm, Michael; Sadowski, Thorsten; Linz, Dominik 分享 收藏
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Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity Qiu, Jiedong; Hauske, Sibylle J.; Zhang, Shiqi; Rodriguez-Nino, Angelica; Albrecht, Thomas; Pastene, Diego O.; van den Born, Jacob; van Goor, Harry; Ruf, Sven; Kohlmann, Markus; Teufel, Michael; Kraemer, Bernhard K.; Hammes, Hans-Peter; Peters, Verena; Yard, Benito A.; Kannt, Aimo 分享 收藏
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders Kannt, Aimo; Rajagopal, Sridharan; Kadnur, Sanjay Venkatachalapathi; Suresh, Juluri; Bhamidipati, Ravi Kanth; Swaminathan, Srinivasan; Hallur, Mahanandeesha Siddappa; Kristam, Rajendra; Elvert, Ralf; Czech, Joerg; Pfenninger, Anja; Rudolph, Christine; Schreuder, Herman; Chandrasekar, Devaraj Venkatapura; Mane, Vishal Subhash; Birudukota, Swarnakumari; Shaik, Shama; Zope, Bharat Ravindra; Burri, Raghunadha Reddy; Anand, Niranjan Naranapura; Thakur, Manish Kumar; Singh, Manvi; Parveen, Reejuana; Kandan, Saravanan; Mullangi, Ramesh; Yura, Takeshi; Gosu, Ramachandraiah; Ruf, Sven; Dhakshinamoorthy, Saravanakumar 分享 收藏
Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels Petrera, Agnese; Gassenhuber, Johann; Ruf, Sven; Gunasekaran, Deepika; Esser, Jennifer; Shahinian, Jasmin Hasmik; Huebschle, Thomas; Ruetten, Hartmut; Sadowski, Thorsten; Schilling, Oliver 分享 收藏
Characterization of RA839, a Noncovalent Small Molecule Binder to Keapl and Selective Activator of Nrf2 Signaling Winkel, Angelika F.; Engel, Christian K.; Margerie, Daniel; Kannt, Aimo; Szillat, Hauke; Glombik, Heiner; Kallus, Christopher; Ruf, Sven; Guessregen, Stefan; Riedel, Jens; Herling, Andreas W.; von Knethen, Andreas; Weigert, Andreas; Bruene, Bernhard; Schmoll, Dieter 分享 收藏
Long-term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats Daniels, Anneleen; Linz, Dominik; van Bilsen, Marc; Ruetten, Hartmut; Sadowski, Thorsten; Ruf, Sven; Juretschke, Hans-Paul; Neumann-Haefelin, Claudia; Munts, Chantal; van der Vusse, Ger J.; van Nieuwenhoven, Frans A. 分享 收藏
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Identification of High-Affinity P2Y12 Antagonists Based on a Phenylpyrazole Glutamic Acid Piperazine Backbone Zech, Gernot; Hessler, Gerhard; Evers, Andreas; Weiss, Tilo; Florian, Peter; Just, Melitta; Czech, Joerg; Czechtizky, Werngard; Goerlitzer, Jochen; Ruf, Sven; Kohlmann, Markus; Nazare, Marc 分享 收藏
Novel β-Amino Acid Derivatives as Inhibitors of Cathepsin A Ruf, Sven; Buning, Christian; Schreuder, Herman; Horstick, Georg; Linz, Wolfgang; Olpp, Thomas; Pernerstorfer, Josef; Hiss, Katrin; Kroll, Katja; Kannt, Aimo; Kohlmann, Markus; Linz, Dominik; Huebschle, Thomas; Ruetten, Hartmut; Wirth, Klaus; Schmidt, Thorsten; Sadowski, Thorsten 分享 收藏
Identification and Synthesis of Novel Inhibitors of Acetyl-CoA Carboxylase with in Vitro and in Vivo Efficacy on Fat Oxidation Keil, Stefanie; Mueller, Marco; Zoller, Gerhard; Haschke, Guido; Schroeter, Katrin; Glien, Maike; Ruf, Sven; Focken, Ingo; Herling, Andreas W.; Schmoll, Dieter 分享 收藏
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