Hira L. Nakhasi - Publications, H-index & Citations

Hira L. Nakhasi

us food and drug administration

48H指数

199论文数

7.1K被引数

收录论文 70

发表时间

Ferroptosis and Nrf-2 signaling: a redox tug of war in leishmaniasis pathogenesis and host directed therapy 铁死亡和Nrf-2信号: 利什曼病发病机制和宿主定向治疗中的氧化还原拉锯战

Redox Biology

IF11.9

2026-02-03

OAAI

M.Junaid Dar; Ryan H. Huston; Nandithadas Purayil; Ashley I. Cronin; Sonia Ashfaq Gondal; Hira L. Nakhasi; Reginaldo Brito; Sreenivas Gannavaram; Abhay R. Satoskar

Maternal milk-derived lipids dictate neonatal macrophage phenotype and function 母乳源性脂质决定新生儿巨噬细胞的表型和功能

iScience

IF4.1

2025-11-14

OAAI

Lunhua Liu; Jiyeon Yang; Jiro Sakai; Ranadhir Dey; Isabelle Coppens; Hira L. Nakhasi; Mustafa Akkoyunlu

Pentalinonsterol alters immune transcriptomic profiles and modulates the Nrf-2 pathway in Leishmania major infected macrophages Pentalinonsterol改变免疫转录组谱，并调节Leishmania major感染的巨噬细胞中的Nrf-2通路

Phytomedicine

IF8.3

2025-10-30

PREAI

M. Junaid Dar; Sreenivas Gannavaram; Ryan H. Huston; Charles Thomas; Hira L Nakhasi; James R. Fuchs; Abhay R. Satoskar

LmCen-/- based vaccine is protective against canine visceral leishmaniasis following three natural exposures in Tunisia

NPJ VACCINES

IF6.5

2025-02-14

OAAI

Boussoffara, Thouraya; Labidi, Imen; Trimeche, Malek; Chelbi, Ifhem; Dachraoui, Khalil; Msallem, Nourhane; Abbas, Mohammed Abdo Saghir; Cherni, Saifedine; Singh, Kamaleshwar P.; Kaviraj, Swarnendu; Dey, Ranadhir; Varikuti, Sanjay; Gannavaram, Sreenivas; da S. Pereira, Lais; Zhang, Wen-Wei; Lypaczewski, Patrick; Hamano, Shinjiro; Kato, Hirotomo; Singh, Sanjay; Louzir, Hechmi; Nakhasi, Hira L.; Satoskar, Abhay R.; Matlashewski, Greg; Zhioua, Elyes

Downregulation of IRF7-mediated type-I interferon response by LmCen-/- parasites is necessary for protective immunity

NPJ VACCINES

IF6.5

2024-12-19

OAAI

Sepahpour, Telly; Alshaweesh, Jalal; Azodi, Nazli; Singh, Komudi; Ireland, Derek D. C.; Valanezhad, Farzaneh; Nakamura, Risa; Satoskar, Abhay R.; Dey, Ranadhir; Hamano, Shinjiro; Nakhasi, Hira L.; Gannavaram, Sreenivas

Identifying Rab2 Protein as a Key Interactor of Centrin1 Essential for Leishmania donovani Growth

ACS INFECTIOUS DISEASES

IF3.8

2024-08-07

PREAI

Roshanara, Rati; Tandon, Rati; Baig, Mirza Sarwar; Das, Sanchita; Srivastava, Rahul; Puri, Niti; Nakhasi, Hira L.; Selvapandiyan, Angamuthu

Manufacturing and preclinical toxicity of GLP grade gene deleted attenuated Leishmania donovani parasite vaccine

SCIENTIFIC REPORTS

IF3.9

2024-06-25

OAAI

Avishek, Kumar; Beg, Mirza A.; Vats, Kavita; Singh, Avinash Kumar; Dey, Ranadhir; Singh, Kamaleshwar P.; Singh, Rajesh Kumar; Gannavaram, Sreenivas; Ramesh, V.; Mulla, Mohmad Sadik A.; Bhatnagar, Upendra; Singh, Sanjay; Nakhasi, Hira L.; Salotra, Poonam; Selvapandiyan, Angamuthu

Immunization with centrin-Deficient Leishmania braziliensis Does Not Protect against Homologous Challenge

VACCINES

IF3.4

2024-03-15

OAAI

Avendano-Rangel, Francys; Agra-Duarte, Gabriela; Borba, Pedro B.; Moitinho, Valdomiro; Avila, Leslye T.; da Silva, Larissa O.; Viana, Sayonara M.; Sharma, Rohit; Gannavaram, Sreenivas; Nakhasi, Hira L.; de Oliveira, Camila I.

The Preclinical Validation of 405 nm Light Parasiticidal Efficacy on Leishmania donovani in Ex Vivo Platelets in a Rag2-/- Mouse Model

MICROORGANISMS

IF4.2

2024-01-29

OAAI

Kaldhone, Pravin R.; Azodi, Nazli; Markle, Hannah L.; Dahiya, Neetu; Stewart, Caitlin; Anderson, John; Macgregor, Scott; Maclean, Michelle; Nakhasi, Hira L.; Gannavaram, Sreenivas; Atreya, Chintamani

Production of leishmanin skin test antigen from Leishmania donovani for future reintroduction in the field 从多诺瓦尼利什曼原虫生产利什曼蛋白皮肤测试抗原，以便将来在野外重新引入

NATURE COMMUNICATIONS

IF15.7

2023-11-02

OAAI

Dey, Ranadhir; Alshaweesh, Jalal; Singh, Kamaleshwar P.; Lypaczewski, Patrick; Karmakar, Subir; Klenow, Laura; Paulini, Kayla; Kaviraj, Swarnendu; Kamhawi, Shaden; Valenzuela, Jesus G.; Singh, Sanjay; Hamano, Shinjiro; Satoskar, Abhay R.; Gannavaram, Sreenivas; Nakhasi, Hira L.; Matlashewski, Greg

Dual-scRNA-seq analysis reveals rare and uncommon parasitized cell populations in chronic L. donovani infection

CELL REPORTS

IF6.9

2023-09-01

OAAI

Karagiannis, Konstantinos; Gannavaram, Sreenivas; Verma, Chaitenya; Pacheco-Fernandez, Thalia; Bhattacharya, Parna; Nakhasi, Hira L.; Satoskar, Abhay R.

Field-Deployable Treatments For Leishmaniasis: Intrinsic Challenges, Recent Developments and Next Steps

RESEARCH AND REPORTS IN TROPICAL MEDICINE

IF4.5

2023-07-01

OAAI

Pacheco-Fernandez, Thalia; Markle, Hannah; Verma, Chaitenya; Huston, Ryan; Gannavaram, Sreenivas; Nakhasi, Hira L.; Satoskar, Abhay R.

Deletion of MIF gene from live attenuated LdCen-/- parasites enhances protective CD4+ T cell immunity

SCIENTIFIC REPORTS

IF3.9

2023-05-05

OAAI

Fiuza, Jacqueline Araujo; Gannavaram, Sreenivas; Gaze, Soraya Torres; de Ornellas, Leticia Gambogi; Alves, Erica Alessandra; Ismail, Nevien; Nakhasi, Hira Lal; Correa-Oliveira, Rodrigo

Toll-like Receptor-9 (TLR-9) Signaling Is Crucial for Inducing Protective Immunity following Immunization with Genetically Modified Live Attenuated Leishmania Parasites

PATHOGENS

IF3.3

2023-03-29

OAAI

Bhattacharya, Parna; Gannavaram, Sreenivas; Ismail, Nevien; Saxena, Ankit; Dagur, Pradeep K.; Akue, Adovi; KuKuruga, Mark; Nakhasi, Hira L.

Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis

NPJ VACCINES

IF6.5

2022-12-03

OAAI

Karmakar, Subir; Volpedo, Greta; Zhang, Wen-Wei; Lypaczewski, Patrick; Ismail, Nevien; Oliveira, Fabiano; Oristian, James; Meneses, Claudio; Gannavaram, Sreenivas; Kamhawi, Shaden; Hamano, Shinjiro; Valenzuela, Jesus G. G.; Matlashewski, Greg; Satoskar, Abhay R. R.; Dey, Ranadhir; Nakhasi, Hira L. L.

The History of Live Attenuated Centrin Gene-Deleted Leishmania Vaccine Candidates

PATHOGENS

IF3.3

2022-04-02

OAAI

Volpedo, Greta; Bhattacharya, Parna; Gannavaram, Sreenivas; Pacheco-Fernandez, Thalia; Oljuskin, Timur; Dey, Ranadhir; Satoskar, Abhay R.; Nakhasi, Hira L.

Leishmania Major Centrin Gene-Deleted Parasites Generate Skin Resident Memory T-Cell Immune Response Analogous to Leishmanization

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-03-28

OAAI

Ismail, Nevien; Karmakar, Subir; Bhattacharya, Parna; Sepahpour, Telly; Takeda, Kazuyo; Hamano, Shinjiro; Matlashewski, Greg; Satoskar, Abhay R.; Gannavaram, Sreenivas; Dey, Ranadhir; Nakhasi, Hira L.

Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis

NPJ VACCINES

IF6.5

2022-03-02

OAAI

Volpedo, Greta; Pacheco-Fernandez, Thalia; Holcomb, Erin A.; Wen-Wei Zhang; Lypaczewski, Patrick; Cox, Blake; Fultz, Rebecca; Mishan, Chelsea; Verma, Chaitenya; Huston, Ryan H.; Wharton, Abigail R.; Dey, Ranadhir; Karmakar, Subir; Oghumu, Steve; Hamano, Shinjiro; Gannavaram, Sreenivas; Nakhasi, Hira L.; Matlashewski, Greg; Satoskar, Abhay R.

Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2022-02-22

OAAI

Bhattacharya, Parna; Ismail, Nevien; Saxena, Ankit; Gannavaram, Sreenivas; Dey, Ranadhir; Oljuskin, Timur; Akue, Adovi; Takeda, Kazuyo; Yu, James; Karmakar, Subir; Dagur, Pradeep K.; McCoy, John Philip; Nakhasi, Hira L.

Determinants of Innate Immunity in Visceral Leishmaniasis and Their Implication in Vaccine Development 内脏利什曼病先天免疫的决定因素及其在疫苗开发中的意义

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-10-12

OAAI

Volpedo, Greta; Pacheco-Fernandez, Thalia; Bhattacharya, Parna; Oljuskin, Timur; Dey, Ranadhir; Gannavaram, Sreenivas; Satoskar, Abhay R.; Nakhasi, Hira L.

研究方向