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收藏A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways
Takasumi, Mika; Omori, Tomoko; Machida, Takeshi; Ishida, Yumi; Hayashi, Manabu; Suzuki, Toshiyuki; Homma, Yoshimi; Endo, Yuichi; Takahashi, Minoru; Ohira, Hiromasa; Fujita, Teizo; Sekine, Hideharu
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收藏Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway
Hayashi, Manabu; Machida, Takeshi; Ishida, Yumi; Ogata, Yusuke; Omori, Tomoko; Takasumi, Mika; Endo, Yuichi; Suzuki, Toshiyuki; Sekimata, Masayuki; Homma, Yoshimi; Ikawa, Masahito; Ohira, Hiromasa; Fujita, Teizo; Sekine, Hideharu
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收藏MASP-1 and MASP-3 play independent roles in activation of the lectin and alternative complement pathwaysMASP-1和MASP-3在凝集素和补体旁路途径的激活中发挥独立作用
Hayashi, Manabu; Ishida, Yumi; Machida, Takeshi; Ogata, Yusuke; Omori, Tomoko; Takasumi, Mika; Endo, Yuichi; Ikawa, Masahito; Ohira, Hiromasa; Fujita, Teizo; Sekine, Hideharu
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收藏siRNA-mediated targeting of hepatocyte mannan-binding lectin-associated serine protease-3 for the treatment of murine collagen-antibody-inducsed arthritis (CAIA), a model for human rheumatoid arthritis
Banda, Nirmal K.; Desai, Dhruv; Casterano, Adam; Scheinman, Robert I.; Acharya, Sumitra; Sekine, Hideharu; Fujita, Teizo; Hansen, Annette G.; Thiel, Steffen; Borodovsky, Anna; Holers, V. Michael
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收藏Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing
Banda, Nirmal K.; Acharya, Sumitra; Scheinman, Robert I.; Mehta, Gaurav; Coulombe, Marilyne; Takahashi, Minoru; Sekine, Hideharu; Thiel, Steffen; Fujita, Teizo; Holers, V. Michael
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收藏CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis
Murayama, Masanori A.; Kakuta, Shigeru; Inoue, Asuka; Umeda, Naoto; Yonezawa, Tomo; Maruhashi, Takumi; Tateishi, Koichiro; Ishigame, Harumichi; Yabe, Rikio; Ikeda, Satoshi; Seno, Akimasa; Chi, Hsi-Hua; Hashiguchi, Yuriko; Kurata, Riho; Tada, Takuya; Kubo, Sachiko; Sato, Nozomi; Liu, Yang; Hattori, Masahira; Saijo, Shinobu; Matsushita, Misao; Fujita, Teizo; Sumida, Takayuki; Iwakura, Yoichiro
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