Martin A. Wear

university of edinburgh

30H指数

76论文数

3.1K被引数

收录论文 35

发表时间

MeCP2 requires interactions with nucleosome linker DNA to read chromatin DNA methylation MeCP2需要与核小体连接DNA相互作用以读取染色质DNA甲基化

Nature Communications

IF15.7

2026-04-17

OAAI

James A. Watson; Beatrice K. Alexander-Howden; Theo S. Hall; Martin A. Wear; Finlay McGhie; Gillian Clifford; Hannah Wapenaar; Juan Zou; Adrian Bird; Marcus D. Wilson

A lymphostatin homologue from Chlamydia pecorum inhibits mitogen-activated bovine T cell proliferation and IFNγ production Chlamydia pecorum来源的淋巴稳定素同系物抑制丝裂原激活的牛T细胞增殖和IFNγ产生

VIRULENCE

IF5.4

2025-05-22

OAAI

Elizabeth A. Blackburn; Cosmin Chintoan-Uta; Andrew G. Bease; Maarten W. Tuijtel; Max Hateley; Martin Wear; David Longbottom; Robin Cassady-Cain; Mark P. Stevens

Identification of novel interferon responsive protein partners of human leukocyte antigen A (HLA-A) using cross-linking mass spectrometry (CLMS) approach 使用交联质谱 (CLMS) 方法鉴定人类白细胞抗原A (hla-a) 的新型干扰素反应蛋白伴侣

SCIENTIFIC REPORTS

IF3.9

2022-11-12

OAAI

Singh, Ashita; Padariya, Monikaben; Faktor, Jakub; Kote, Sachin; Mikac, Sara; Dziadosz, Alicja; Lam, Tak W.; Brydon, Jack; Wear, Martin A.; Ball, Kathryn L.; Hupp, Ted; Sznarkowska, Alicja; Vojtesek, Borek; Kalathiya, Umesh

Pilot scale production, extraction and purification of a thermostable phycocyanin from Synechocystis sp. PCC 6803

BIORESOURCE TECHNOLOGY

IF9

2022-02-01

OAAI

Puzorjov, Anton; Unal, Suleyman Mert; Wear, Martin A.; McCormick, Alistair J.

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice 速效变构磷酸果糖激酶抑制剂阻断锥虫糖酵解并治愈小鼠急性非洲锥虫病

NATURE COMMUNICATIONS

IF15.7

2021-02-16

OAAI

McNae, Iain W.; Kinkead, James; Malik, Divya; Yen, Li-Hsuan; Walker, Martin K.; Swain, Chris; Webster, Scott P.; Gray, Nick; Fernandes, Peter M.; Myburgh, Elmarie; Blackburn, Elizabeth A.; Ritchie, Ryan; Austin, Carol; Wear, Martin A.; Highton, Adrian J.; Keats, Andrew J.; Vong, Antonio; Dornan, Jacqueline; Mottram, Jeremy C.; Michels, Paul A. M.; Pettit, Simon; Walkinshaw, Malcolm D.

A Truncated Form of HpARI Stabilizes IL-33, Amplifying Responses to the Cytokine 截短形式的HpARI稳定IL-33，放大对细胞因子的反应

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-06-30

OAAI

Chauche, Caroline; Vacca, Francesco; Chia, Shin Li; Richards, Josh; Gregory, William F.; Ogunkanbi, Adefunke; Wear, Martin; McSorley, Henry J.

A helminth-derived suppressor of ST2 blocks allergic responses

ELIFE

IF0

2020-05-18

OAAI

Vacca, Francesco; Chauche, Caroline; Jamwal, Abhishek; Hinchy, Elizabeth C.; Heieis, Graham; Webster, Holly; Ogunkanbr, Adefunke; Sekne, Zala; Gregory, William F.; Wear, Martin; Perona-Wright, Georgia; Higgins, Matthew K.; Nys, Josquin A.; Cohen, E. Suzanne; McSorley, Henry J.

Kinetic and structural studies of Trypanosoma and Leishmania phosphofructokinases show evolutionary divergence and identify AMP as a switch regulating glycolysis versus gluconeogenesis 锥虫和利什曼原虫磷酸果糖激酶的动力学和结构研究显示出进化差异，并将AMP确定为调节糖酵解与糖异生的开关

FEBS JOURNAL

IF4.2

2020-01-08

OAAI

Fernandes, Peter M.; Kinkead, James; McNae, Iain W.; Vasquez-Valdivieso, Monserrat; Wear, Martin A.; Michels, Paul A. M.; Walkinshaw, Malcolm D.

Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex

JOURNAL OF CELL BIOLOGY

IF6.4

2019-09-30

OAAI

Abad, Maria A.; Ruppert, Jan G.; Buzuk, Lana; Wear, Martin; Zou, Juan; Webb, Kim M.; Kelly, David A.; Voigt, Philipp; Rappsilber, Juri; Earnshaw, William C.; Jeyaprakash, A. Arockia

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

CHEMICAL SCIENCE

IF7.4

2019-01-01

OAAI

De Simone, Alessio; Georgiou, Charis; Ioannidis, Harris; Gupta, Arun A.; Juarez-Jimenez, Jordi; Doughty-Shenton, Dahlia; Blackburn, Elizabeth A.; Wear, Martin A.; Richards, Jonathan P.; Barlow, Paul N.; Carragher, Neil; Walkinshaw, Malcolm D.; Hulme, Alison N.; Michel, Julien

A chicken bioreactor for efficient production of functional cytokines

BMC BIOTECHNOLOGY

IF3.4

2018-12-29

OAAI

Herron, Lissa R.; Pridans, Clare; Turnbull, Matthew L.; Smith, Nikki; Lillico, Simon; Sherman, Adrian; Gilhooley, Hazel J.; Wear, Martin; Kurian, Dominic; Papadakos, Grigorios; Digard, Paul; Hume, David A.; Gill, Andrew C.; Sang, Helen M.

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation 半胱氨酸氧化和S-亚硝化对丙酮酸激酶M2的氧化还原调节

BIOCHEMICAL JOURNAL

IF4.3

2018-10-31

OAAI

Mitchell, Alice Rose; Yuan, Meng; Morgan, Hugh P.; McNae, Iain W.; Blackburn, Elizabeth A.; Le Bihan, Thierry; Homem, Rafael A.; Yu, Manda; Loake, Gary J.; Michels, Paul A.; Wear, Martin A.; Walkinshaw, Malcolm D.

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor M2丙酮酸激酶作为氨基酸传感器的同种异体机制

BIOCHEMICAL JOURNAL

IF4.3

2018-05-31

OAAI

Yuan, Meng; McNae, Iain W.; Chen, Yiyuan; Blackburn, Elizabeth A.; Wear, Martin A.; Michels, Paul A. M.; Fothergill-Gilmore, Linda A.; Hupp, Ted; Walkinshaw, Malcolm D.

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

IMMUNITY

IF26.3

2017-10-01

140

OAAI

Osbourn, Megan; Soares, Dinesh C.; Vacca, Francesco; Cohen, E. Suzanne; Scott, Ian C.; Gregory, William F.; Smyth, Danielle J.; Toivakka, Matilda; Kemter, Andrea M.; Le Bihan, Thierry; Wear, Martin; Hoving, Dennis; Filbey, Kara J.; Hewitson, James P.; Henderson, Holly; Gonzalez-Ciscar, Andrea; Errington, Claire; Vermeren, Sonja; Astier, Anne L.; Wallace, William A.; Schwarze, Jurgen; Ivens, Alasdair C.; Maizels, Rick M.; McSorley, Henry J.

Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition Mis18复合物组装和cenp-a沉积Cdk1-regulated时机的分子基础

EMBO REPORTS

IF6.2

2017-04-04

OAAI

Spiller, Frances; Medina-Pritchard, Bethan; Abad, Maria Alba; Wear, Martin A.; Molina, Oscar; Earnshaw, William C.; Jeyaprakash, A. Arockia

Biophysical Characterization and Activity of Lymphostatin, a Multifunctional Virulence Factor of Attaching and Effacing Escherichia coli

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-03-01

OAAI

Cassady-Cain, Robin L.; Blackburn, Elizabeth A.; Alsarraf, Husam; Dedic, Emil; Bease, Andrew G.; Boettcher, Bettina; Jorgensen, Rene; Wear, Martin; Stevens, Mark P.

Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90

BIOSCIENCE REPORTS

IF4.7

2015-10-19

OAAI

Blackburn, Elizabeth A.; Wear, Martin A.; Landre, Vivian; Narayan, Vikram; Ning, Jia; Erman, Burak; Ball, Kathryn L.; Walkinshaw, Malcolm D.

Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance

DNA REPAIR

IF2.7

2015-07-01

OAAI

McNeil, Ewan M.; Astell, Katy R.; Ritchie, Ann-Marie; Shave, Steven; Houston, Douglas R.; Bakrania, Preeti; Jones, Hayley M.; Khurana, Puneet; Wallace, Claire; Chapman, Tim; Wear, Martin A.; Walkinshaw, Malcolm D.; Saxty, Barbara; Melton, David W.

M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-03-25

146

OAAI

Morgan, Hugh P.; O'Reilly, Francis J.; Wear, Martin A.; O'Neill, J. Robert; Fothergill-Gilmore, Linda A.; Hupp, Ted; Walkinshaw, Malcolm D.

A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase

BIOCHEMICAL JOURNAL

IF4.3

2012-10-18

OAAI

Morgan, Hugh P.; Walsh, Martin J.; Blackburn, Elizabeth A.; Wear, Martin A.; Boxer, Matthew B.; Shen, Min; Veith, Henrike; McNae, Iain W.; Nowicki, Matthew W.; Michels, Paul A. M.; Auld, Douglas S.; Fothergill-Gilmore, Linda A.; Walkinshaw, Malcolm D.

研究方向