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D

David R. Spriggs

massachusetts general hospital cancer center

71H指数
425论文数
1.7W被引数
收录论文 60
发表时间
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Hypoxia induced VEGF secretion promotes resistance to bispecific T-cell engagers缺氧诱导的VEGF分泌促进对双特异性T细胞衔接器的抵抗
errSignal Transduction and Targeted Therapy
IF52.7
err2025-12-19
err0
errOAAI
errMengyao Xu; Syem K. Barakzai; Raj Kumar; Irva Veillard; Eugene Kim; Amy Bregar; Eric Eisenhauer; Richard Penson; Sara Bouberhan; Jennifer Filipi; Tina Colella; Tim Bond; Caroline Clark; Lawrence H. Lin; Jinpeng Ruan; Cheng Wang; Xingping Qin; Kristopher Sarosiek; Bo Rueda; Cesar Castro; David R. Spriggs; Oladapo O. Yeku
err分享
err收藏
Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy (vol 82, pg 773, 2022)
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
errOAAI
errZhang, Songfa; Yan, Chuan; Millar, David G.; Yang, Qiqi; Heather, James M.; Langenbucher, Adam; Morton, Laura T.; Sepulveda, Sean; Alpert, Eric; Whelton, Lauren R.; Zarrella, Dominique T.; Guo, Mei; Minogue, Eleanor; Lawrence, Michael S.; Rueda, Bo R.; Spriggs, David R.; Lu, Weiguo; Langenau, David M.; Cobbold, Mark
err分享
err收藏
Sialyl-Tn serves as a potential therapeutic target for ovarian cancer
errJOURNAL OF OVARIAN RESEARCH
IF4.2
err2024-04-02
err3
errOAAI
errAl-Alem, Linah; Prendergast, Jillian M.; Clark, Justin; Zarrella, Bianca; Zarrella, Dominique T.; Hill, Sarah J.; Growdon, Whitfield B.; Pooladanda, Venkatesh; Spriggs, David R.; Cramer, Daniel; Elias, Kevin M.; Nazer, Rawan I.; Skates, Steven J.; Behrens, Jeff; Dransfield, Daniel T.; Rueda, Bo R.
err分享
err收藏
Hypoxia-induced downregulation of MUC16: A key player in bispecific T-cell engager resistance in ovarian cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errXu, Mengyao; Barakzai, Syem K.; Kononenko, Artem; Kumar, Raj; Veillard, Irva; Kim, Eugene; Bond, Timothy S.; Spriggs, David R.; Rueda, Bo R.; Yeku, Oladapo
err分享
err收藏
Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma
errBRITISH JOURNAL OF CANCER
IF6.8
err2024-03-04
err2
errOAAI
errMatoba, Yusuke; Zarrella, Dominique T.; Pooladanda, Venkatesh; Mohammadabadi, Maryam Azimi; Kim, Eugene; Kumar, Shaan; Xu, Mengyao; Qin, Xingping; Ray, Lauren J.; Devins, Kyle M.; Kumar, Raj; Kononenko, Artem; Eisenhauer, Eric; Veillard, Irva E.; Yamagami, Wataru; Hill, Sarah J.; Sarosiek, Kristopher A.; Yeku, Oladapo O.; Spriggs, David R.; Rueda, Bo R.
err分享
err收藏
Structural basis for antibody recognition of the proximal MUC16 ectodomain
errJOURNAL OF OVARIAN RESEARCH
IF4.2
err2024-02-19
err3
errOAAI
errLee, Kwangkook; Perry, Kay; Xu, Mengyao; Veillard, Irva; Kumar, Raj; Rao, Thapi Dharma; Rueda, Bo R.; Spriggs, David R.; Yeku, Oladapo O.
err分享
err收藏
Loss of galectin 3 reveals its potential roles in the aggressive pathology of uterine serous carcinoma
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errMatoba, Yusuke; Zarrella, Dominique T.; Pooladanda, Venkatesh; Kim, Eugene; Kumar, Shaan; Xu, Mengyao; Qin, Xingping; Kumar, Raj; Kononenko, Artem; Veillard, Irva; Sarosiek, Kristopher; Yeku, Oladapo; Spriggs, David R.; Rueda, Bo R.
err分享
err收藏
Dual Fluorescence Isogenic Synthetic Lethal Kinase Screen and High-Content Secondary Screening for MUC16/CA125-Selective Agents
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2022-04-12
err0
errOAAI
errRao, Thapi D.; Xu, Mengyao; Eng, Stephanie; Yang, Guangli; Manson, Robin; Rosales, Nestor; Kumar, Raj; Veillard, Irva E.; Zhou, Qin; Iasonos, Alexia; Ouerfelli, Ouathek; Djaballah, Hakim; Spriggs, David R.; Yeku, Oladapo O.
err分享
err收藏
Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy
errCANCER RESEARCH
IF16.6
err2021-12-29
err7
errOAAI
errZhang, Songfa; Yan, Chuan; Millar, David G.; Yang, Qiqi; Heather, James M.; Langenbucher, Adam; Morton, Laura T.; Sepulveda, Sean; Alpert, Eric; Whelton, Lauren R.; Zarrella, Dominique T.; Guo, Mei; Minogue, Eleanor; Lawrence, Michael S.; Rueda, Bo R.; Spriggs, David R.; Lu, Weiguo; Langenau, David M.; Cobbold, Mark
err分享
err收藏
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition针对MUC16的双特异性T细胞接合抗体在单一疗法以及与PD-1和VEGF抑制联合治疗中显示出对卵巢癌的功效
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2021-04-14
err29
errOAAI
errYeku, Oladapo O.; Rao, Thapi Dharma; Laster, Ian; Kononenko, Artem; Purdon, Terence J.; Wang, Pei; Cui, Ziyou; Liu, Hong; Brentjens, Renier J.; Spriggs, David
err分享
err收藏
Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies
errSCIENTIFIC REPORTS
IF3.9
err2021-02-12
err19
errOAAI
errStasenko, Marina; Smith, Evan; Yeku, Oladapo; Park, Kay J.; Laster, Ian; Lee, Kwangkook; Walderich, Sven; Spriggs, Elizabeth; Rueda, Bo; Weigelt, Britta; Zamarin, Dmitriy; Rao, Thapi Dharma; Spriggs, David R.
err分享
err收藏
A phase 2 study of combined chemo-immunotherapy with cisplatin-pembrolizumab and radiation for unresectable vulvar squamous cell carcinoma
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2020-09-14
err13
errOAAI
errYeku, Oladapo; Russo, Andrea L.; Lee, Hang; Spriggs, David
err分享
err收藏
Development of novel and improved monoclonal antiMUC16 antibodies for the targeted therapy of ovarian cancer
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errLaster, Ian; Yeku, Oladapo; Spriggs, David
err分享
err收藏
Radiopharmacologic screening of antibodies to the unshed ectodomain of MUC16 in ovarian cancer identifies a lead candidate for clinical translation
errNUCLEAR MEDICINE AND BIOLOGY
IF3
err2020-07-01
err5
errOAAI
errNemieboka, Brandon; Sharma, Sai Kiran; Rao, Thapi Dharma; Edwards, Kimberly J.; Yan, Su; Wang, Pei; Ragupathi, Ashwin; Piersigilli, Alessandra; Spriggs, David R.; Lewis, Jason S.
err分享
err收藏
Utilizing a novel highly specific sialyl-Tn ELISA as a diagnostic for ovarian cancer
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errAl-Alem, Linah F.; Prendergast, Jillian; Clark, Justin; Zarrella, Bianca; Dransfield, Dan; Growdon, Whitfield; Spriggs, David; Eisenhauer, Eric; Behrens, Jeff; Rueda, Bo R.
err分享
err收藏
Case 18-2019: A 24-Year-Old Woman with a Pelvic Mass
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2019-06-13
err0
PREAI
errSpriggs, David R.; Melamed, Alexander; Li, Weier; Safdar, Nida
err分享
err收藏
Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference卵巢癌研究和治疗中的关键问题: 美国癌症研究协会特别会议的报告
errCANCER
IF5.1
err2019-03-05
err40
errOAAI
errBast, Robert C., Jr.; Matulonis, Ursula A.; Sood, Anil K.; Ahmed, Ahmed A.; Amobi, Adaobi E.; Balkwill, Frances R.; Wielgos-Bonvallet, Monicka; Bowtell, David D. L.; Brenton, James D.; Brugge, Joan S.; Coleman, Robert L.; Draetta, Giulio F.; Doberstein, Kai; Drapkin, Ronny I.; Eckert, Mark A.; Edwards, Robert P.; Elias, Kevin M.; Ennis, Darren; Futreal, Andrew; Gershenson, David M.; Greenberg, Roger A.; Huntsman, David G.; Ji, Jennifer Xiao Ye; Kohn, Elise C.; Iavarone, Claudia; Lengyel, Ernst R.; Levine, Douglas A.; Lord, Christopher J.; Lu, Zhen; Mills, Gordon B.; Modugno, Francesmary; Nelson, Brad H.; Odunsi, Kunle; Pilsworth, Jessica A.; Rottapel, Robert K.; Powell, Daniel J., Jr.; Shen, Li; Shih, Ie-Ming; Spriggs, David R.; Walton, Josephine; Zhang, Kaiyang; Zhang, Rugang; Zou, Lee
err分享
err收藏
Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-01-18
err180
errOAAI
errZhao, Yanxia; Cao, Jinghong; Melamed, Alexander; Worley, Michael; Gockley, Allison; Jones, Dennis; Nia, Hadi T.; Zhang, Yanling; Stylianopoulos, Triantafyllos; Kumar, Ashwin S.; Mpekris, Fotios; Datta, Meenal; Sun, Yao; Wu, Limeng; Gao, Xing; Yeku, Oladapo; del Carmen, Marcela G.; Spriggs, David R.; Jain, Rakesh K.; Xu, Lei
err分享
err收藏
Progress in BRCA-Mutated Ovarian Cancer
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2018-12-27
err13
PREAI
errSpriggs, David R.; Longo, Dan L.
err分享
err收藏
High-affinity anti-galectin-3 antibodies targeting oncogenic properties in serous ovarian cancer
errCANCER RESEARCH
IF16.6
err2018-07-01
err0
PREAI
errThapi, Dharmarao; Stasenko, Marina; White, Thomas; Walderich, Sven J.; Feit, Noah; Weis-Garcia, Frances; Spriggs, David R.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
G
Gordon B. Mills
H 指数: 231 · 论文数: 3.5K
R
Rakesh K. Jain
H 指数: 200 · 论文数: 1.7K
C
Chris Sander
H 指数: 191 · 论文数: 849
A
Anil K. Sood
H 指数: 174 · 论文数: 3.3K
N
Nikolaus Schultz
H 指数: 162 · 论文数: 1.8K
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