John J. Letterio - Publications, H-index & Citations

John J. Letterio

university hospitals rainbow babies & children's hospital

61H指数

179论文数

1.6W被引数

收录论文 67

发表时间

The Dendritic Cell-based Vaccine PROTEXI leverages Antiviral CD4 T cell Memory to boost anti-tumor immune responses in mice 树突状细胞疫苗PROTEXI利用抗病毒CD4 T细胞记忆增强小鼠抗肿瘤免疫应答

Nature Communications

IF15.7

2026-07-27

OAAI

Jin Muk Kang; Eun Hyang Han; Jin-Kyu Choi; Seunghee Youm; Tej Pareek; Liraz Levi; Seong-Jin Kim; John Letterio; Seunghwan Lim

A Core NRF2 Gene Set Defined Through Comprehensive Transcriptomic Analysis Predicts Selective Drug Resistance and Poor Multicancer Prognosis

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2024-12-01

PREAI

Luo, George; Kumar, Harshita; Aldridge, Kristin; Rieger, Stevie; Han, EunHyang; Jiang, Ethan; Chan, Ernest R.; Soliman, Ahmed; Mahdi, Haider; Letterio, John J.

Novel combination therapy for treating proteasome inhibitor-resistant multiple myeloma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Kim, Byung-Gyu; Choi, Sung Hee; Huong Nguyen; Liang, Fu-Sen; Kim, Seong-Jin; Letterio, John; Huang, Alex

Tm4sf19 deficiency inhibits osteoclast multinucleation and prevents bone loss

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2024-02-01

OAAI

Park, Sujin; Heo, Jin Sun; Mizuno, Seiya; Kim, Minwoo; An, Haein; Hong, Eunji; Kang, Min Gi; Kim, Junil; Yun, Rebecca; Park, Hyeyeon; Noh, Eun Hye; Lee, Min Jung; Yoon, Kwiyeom; Kim, Pyunggang; Son, Minjung; Pang, Kyoungwha; Lee, Jihee; Park, Jinah; Ooshima, Akira; Kim, Tae-Jin; Park, Je Yeon; Yang, Kyung-Min; Myung, Seung-Jae; Bae, Hyun; Lee, Kyung-Mi; Letterio, John; Park, Seok Hee; Takahashi, Satoru; Kim, Seong-Jin

The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma

MOLECULAR ONCOLOGY

IF4.5

2023-06-13

OAAI

Luo, George; Aldridge, Kristin; Chen, Toby; Aslot, Vivek; Kim, Byung-Gyu; Han, Eun Hyang; Singh, Neelima; Li, Sai; Xiao, Tsan Sam; Sporn, Michael B.; Letterio, John J.

Are NCI Cancer Centers Providing Adolescents and Young Adults With Cancer Focused Clinical Services? A National Survey

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK

IF16.4

2023-05-01

OAAI

Daunov, Katherine; Daunov, Michael; Noskoff, Kara; Gan, Hilary; Davies, Simon; Farrell, Megan; Hadley, Whitney; Baffa, Amelia; Giesel, Jennifer; Egler, Rachel; Huang, Alex Y.; Letterio, John J.; Lee, Richard T.

Smad4-deficient T cells promote colitis-associated colon cancer via an IFN-γ-dependent suppression of 15-hydroxyprostaglandin dehydrogenase Smad4-deficient T细胞通过ifn-γ 依赖性抑制15-羟基前列腺素脱氢酶促进结肠炎相关的结肠癌

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-08-15

OAAI

Choi, Sung Hee; Huang, Alex Y.; Letterio, John J.; Kim, Byung-Gyu

O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells

GLYCOBIOLOGY

IF3.3

2020-12-22

OAAI

Yu, Shuiliang; Wang, Weihuan; Albakri, Marwah; Yu, Xiaoxing; Majihail, Gurnoor; Lim, Seunghwan; Lopilato, Rachel K.; Ito, Atsuko; Letterio, John; Haltiwanger, Robert S.; Zhou, Lan

Loss of p27Kip1 leads to expansion of CD4+effector memory T cells and accelerates colitis-associated colon cancer in mice with a T cell lineage restricted deletion of Smad4

ONCOIMMUNOLOGY

IF6.3

2020-12-03

OAAI

Choi, Sung Hee; Barker, Emily C.; Gerber, Kyle J.; Letterio, John J.; Kim, Byung-Gyu

A novel combination therapy for treating advanced drug resistant acute lymphoblastic leukemia

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Vicioso, Yorleny M.; Beck, Rose; Gram, Herman; Asthana, Abhishek; Zhang, Keman; Wong, Derek; Letterio, John; Parameswaran, Reshmi

Nrf2-mediated metabolic reprogramming of tolerogenic dendritic cells is protective against aplastic anemia

JOURNAL OF AUTOIMMUNITY

IF7

2018-11-01

OAAI

Wei, Hsi-Ju; Gupta, Ashish; Kao, Wei-Ming; Almudallal, Omar; Letterio, John J.; Pareek, Tej K.

Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation

CARCINOGENESIS

IF2.9

2017-10-21

OAAI

Barker, Emily C.; Kim, Byung-Gyu; Yoon, Ji Hee; Tochtrop, Gregory P.; Letterio, John J.; Choi, Sung Hee

A unique tolerizing dendritic cell phenotype induced by the synthetic triterpenoid CDDO-DFPA (RTA-408) is protective against EAE

SCIENTIFIC REPORTS

IF3.9

2017-08-29

OAAI

Wei, Hsi-Ju; Pareek, Tej K.; Liu, Qi; Letterio, John J.

Myeloid-derived suppressor cells: The green light for myeloma immune escape 髓源性抑制细胞: 骨髓瘤免疫逃逸的绿灯

BLOOD REVIEWS

IF5.7

2016-09-01

108

OAAI

Malek, Ehsan; de Lima, Marcos; Letterio, John J.; Kim, Byung-Gyu; Finke, James H.; Driscoll, James J.; Giralt, Sergio A.

A novel 3D osteoblastic niche assay is useful to study the characteristics of bone metastatic cancers

CANCER RESEARCH

IF16.6

2016-05-26

PREAI

Lim, Seunghwan; Pareek, Tej; Palassery, Rasmi; Letterio, John

Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727 细胞周期蛋白依赖性激酶5通过Stat3在丝氨酸727的特异性磷酸化抑制Foxp3基因表达和Treg发育

MOLECULAR IMMUNOLOGY

IF3

2015-10-01

OAAI

Lam, Eric; Choi, Sung Hee; Pareek, Tej K.; Kim, Byung-Gyu; Letterio, John J.

Hepatic Stellate Cells Inhibit T Cells through Active TGF-β1 from a Cell Surface-Bound Latent TGF-β1/GARP Complex

JOURNAL OF IMMUNOLOGY

IF3.4

2015-09-15

OAAI

Li, Yan; Kim, Byung-Gyu; Qian, Shiguang; Letterio, John J.; Fung, John J.; Lu, Lina; Lin, Feng

Suppression of colitis-associated colon carcinogenesis by the natural triterpenoid celastrol

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Choi, Sung Hee; Baker, Emily; Kim, Byung-Gyu; Tochtrop, Gregory; Letterio, John J.

Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex

CELL CYCLE

IF3.4

2015-04-18

OAAI

Lam, Eric; Pareek, Tej K.; Letterio, John J.

Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011

NEURO-ONCOLOGY

IF13.4

2014-12-24

4.3K

OAAI

Ostrom, Quinn T.; de Blank, Peter M.; Kruchko, Carol; Petersen, Claire M.; Liao, Peter; Finlay, Jonathan L.; Stearns, Duncan S.; Wolff, Johannes E.; Wolinsky, Yingli; Letterio, John J.; Barnholtz-Sloan, Jill S.

研究方向