David M. Spencer - Publications, H-index & Citations

David M. Spencer

Baylor College of Medicine

52H指数

240论文数

1.0W被引数

收录论文 72

发表时间

Targeting tonsillar B cells with IL-9 and IL-33 enhances the rhesus macaque humoral response to DNA/protein-based HIV envelope vaccine

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

PREAI

Kobie, James; Spencer, David; Barnette, Philip; Pandey, Shilpi; Basu, Madhubanti; Sutton, William; Rangel-Moreno, Javier; Haigwood, Nancy Logan; Hessell, Ann Jones; Sarkar, Sanghita

Engineering Tolerance toward Allogeneic CAR-T Cells by Regulation of MHC Surface Expression with Human Herpes Virus-8 Proteins

MOLECULAR THERAPY

IF12

2021-02-01

OAAI

Wang, Xiaomei; Cabrera, Fabricio G.; Sharp, Kelly L.; Spencer, David M.; Foster, Aaron E.; Bayle, J. Henri

Small molecule inducible MyD88/CD40 (iMC) in CAR-T cells can repolarize M2 macrophage to an anti-tumor M1 phenotype

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Wang, Xiaohong; Gabrusiewicz, Konrad; Spencer, David M.; Foster, Aaron E.; Bayle, J. Henri

Inducible MyD88/CD40 synergizes with IL-15 to enhance antitumor efficacy of CAR-NK cells

BLOOD ADVANCES

IF7.1

2020-05-08

OAAI

Wang, Xiaomei; Jasinski, Daniel L.; Medina, Jan L.; Spencer, David M.; Foster, Aaron E.; Bayle, J. Henri

Two-Dimensional Regulation of CAR-T Cell Therapy with Orthogonal Switches

MOLECULAR THERAPY-ONCOLYTICS

IF0

2019-03-01

OAAI

Duong, Mylinh T.; Collinson-Pautz, Matthew R.; Morschl, Eva; Lu, An; Szymanski, Slawomir P.; Zhang, Ming; Brandt, Mary E.; Chang, Wei-Chun; Sharp, Kelly L.; Toler, Steven M.; Slawin, Kevin M.; Foster, Aaron E.; Spencer, David M.; Bayle, J. Henri

Constitutively active MyD88/CD40 costimulation enhances expansion and efficacy of chimeric antigen receptor T cells targeting hematological malignancies 组成型活性MyD88/CD40共刺激增强靶向血液系统恶性肿瘤的嵌合抗原受体T细胞的扩增和功效

LEUKEMIA

IF13.4

2019-02-28

OAAI

Collinson-Pautz, Matthew R.; Chang, Wei-Chun; Lul, An; Khalil, Mariam; Crisostomo, Jeannette W.; Li, Pei-Yi; Mahendravada, Aruna; Shinners, Nicholas P.; Brandt, Mary E.; Zhang, Ming; MyLinh Duong; Bayle, J. Henri; Slawin, Kevin M.; Spencer, David M.; Foster, Aaron E.

Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models

CANCER DISCOVERY

IF33.3

2017-11-01

146

OAAI

Mata, Melinda; Gerken, Claudia; Phuong Nguyen; Krenciute, Giedre; Spencer, David M.; Gottschalk, Stephen

Centrally Determined Standardization of Flow Cytometry Methods Reduces Interlaboratory Variation in a Prospective Multicenter Study

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY

IF3

2017-11-01

OAAI

Westera, Liset; van Viegen, Tanja; Jeyarajah, Jenny; Azad, Azar; Bilsborough, Janine; van den Brink, Gijs R.; Cremer, Jonathan; Danese, Silvio; D'Haens, Geert; Eckmann, Lars; Faubion, William; Filice, Melissa; Korf, Hannelie; McGovern, Dermot; Panes, Julian; Salas, Azucena; Sandborn, William J.; Silverberg, Mark S.; Smith, Michelle I.; Vermeire, Severine; Vetrano, Stefania; Shackelton, Lisa M.; Stitt, Larry; Jairath, Vipul; Levesque, Barrett G.; Spencer, David M.; Feagan, Brian G.; Casteele, Niels Vande

Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40

MOLECULAR THERAPY

IF12

2017-09-01

OAAI

Foster, Aaron E.; Mahendravada, Aruna; Shinners, Nicholas P.; Chang, Wei-Chun; Crisostomo, Jeannette; Lu, An; Khalil, Mariam; Morschl, Eva; Shaw, Joanne L.; Saha, Sunandan; Duong, MyLinh T.; Collinson-Pautz, Matthew R.; Torres, David L.; Rodriguez, Tania; Pentcheva-Hoang, Tsvetelina; Bayle, J. Henri; Slawin, Kevin M.; Spencer, David M.

Dual-switchGoCAR- T cells: small molecule-regulated GO and STOP switches to target solid cancer in vivo

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Duong, MyLinh T.; Collinson-Pautz, Matthew R.; Morschl, Eva; Brandt, Mary E.; Zhang, Ming; Slawin, Kevin W.; Foster, Aaron E.; Bayle, J. Henri; Spencer, David M.

Dual-switch TCR: A two-ligand system to control PRAME TCR-modified T cell proliferation and death using inducible MyD88/ CD40 and caspase-9

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Pentcheva-Hoang, Tsvetelina; Rodriguez, Tania; Torres, David; Korngold, Ana; Crisostomo, Jeannette; Duong, MyLinh T.; Collinson-Pautz, Matthew; Bayle, J. Henri; Heemskerk, Mirjam H. M.; Falkenburg, J. H. Frederik; Moseley, Annemarie; Slawin, Kevin M.; Spencer, David; Foster, Aaron E.

CENTRALLY-DETERMINED STANDARDIZATION OF FLOW CYTOMETRY METHODS REDUCES INTER-LABORATORY VARIATION IN A PROSPECTIVE MULTICENTER STUDY

GASTROENTEROLOGY

IF25.1

2017-04-01

OAAI

Westera, Liset; van Viegen, Tanja; Jeyarajah, Jenny; Azad, Azar; Bilsborough, Janine; van den Brink, Gijs; Danese, Silvio; D'Haens, Geert R.; Eckmann, Lars; Faubion, William; Korf, Hannelie; McGovern, Dermot; Panes, Julian; Salas, Azucena; Sandborn, William J.; Silverberg, Mark S.; Smith, Michelle I.; Vermeire, Severine; Vetrano, Stefania; Shackelton, Lisa; Stitt, Larry; Jairath, Vipul; Levesque, Barrett; Spencer, David; Feagan, Brian G.; Casteele, Niels Vande

Go-TOR™: Inducible MyD88/CD40 (iMC) enhances proliferation and survival of tumor-specific TCR-modified T cells, increasing anti-tumor efficacy

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Spencer, David M.; Hoang, Tsvetelina P.; Foster, Aaron; Rodriguez, Tania; Torres, David; Lu, An; Crisostomo, Jeannette; Jahn, Lorenz; Heemskerk, Mirjam H. M.

Go-TCR: Inducible MyD88/CD40 (iMC) Enhances Proliferation and Survival of Tumor-Specific TCR-Modified T Cells, Increasing Anti-Tumor Efficacy

MOLECULAR THERAPY

IF12

2016-05-01

OAAI

Hoang, Tsvetelina P.; Foster, Aaron; Rodriguez, Tania; Torres, David; Lu, An; Crisostomo, Jeannette; Jahn, Lorenz; Heemskerk, Mirjam H. M.; Spencer, David M.

Engineering MEDI6383; a novel, multivalent immune-modulating fusion protein that potently agonizes the TNFRSF receptor OX40

EUROPEAN JOURNAL OF CANCER

IF7.1

2015-09-01

PREAI

Damschroder, M.; Oberst, M.; Stracener, C.; Du, Q.; Spencer, D.; Woods, R.; Auge, C.; Mulgrew, K.; Hair, J.; Wu, H.; Hammond, S.; Dall'Acqua, W.

Inducible Caspase-9 Suicide Gene Controls Adverse Effects from Alloreplete T Cells after Haploidentical Stem Cell Transplantation

MOLECULAR THERAPY

IF12

2015-05-01

OAAI

Zhou, Xiaoou; Dotti, Gianpietro; Krance, Robert A.; Martinez, Caridad; Kamble, Rammurti T.; Naik, Swati; Durett, April G.; Dakhova, Olga; Savoldo, Barbara; Di Stasi, Antonio; Spencer, David M.; Lin, Yu-Feng; Liu, Hao; Grilley, Bambi J.; Gee, Adrian P.; Rooney, Cliona M.; Heslop, Helen E.; Brenner, Malcolm K.

Regulated Apoptosis of Genetically Modified Hematopoietic Stem and Progenitor Cells Via an Inducible Caspase-9 Suicide Gene in Rhesus Macaques

Stem Cells

IF3.6

2014-12-18

OAAI

Barese, Cecilia N.; Felizardo, Tania C.; Sellers, Stephanie E.; Keyvanfar, Keyvan; Di Stasi, Antonio; Metzger, Mark E.; Krouse, Allen E.; Donahue, Robert E.; Spencer, David M.; Dunbar, Cynthia E.

Paths of FGFR-driven tumorigenesis

CELL CYCLE

IF3.4

2014-10-28

136

OAAI

Acevedo, Victor D.; Ittmann, Michael; Spencer, David M.

Activation of antigen-exposed iMC-DCs at the right place and right time promotes potent anti-tumor immunity

ONCOIMMUNOLOGY

IF6.3

2014-10-27

OAAI

Spencer, David M.

FGFR1-WNT-TGF-β Signaling in Prostate Cancer Mouse Models Recapitulates Human Reactive Stroma

CANCER RESEARCH

IF16.6

2014-01-16

OAAI

Carstens, Julienne L.; Shahi, Payam; Van Tsang, Susan; Smith, Billie; Creighton, Chad J.; Zhang, Yiqun; Seamans, Amber; Seethammagari, Mamatha; Vedula, Indira; Levitt, Jonathan M.; Ittmann, Michael M.; Rowley, David R.; Spencer, David M.

研究方向