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Therapeutic drug monitoring of meropenem and piperacillin-tazobactam in the Singapore critically ill population-A prospective, multi-center, observational study (BLAST 1) Chua, Nathalie Grace; Loo, Liwen; Hee, Daryl Kim Hor; Lim, Tze Peng; Ng, Tat Ming; Hoo, Grace Si Ru; Soong, Jie Lin; Ong, Jasmine Chiat Ling; Tang, Sarah Si Lin; Zhou, Yvonne Peijun; Lee, Winnie; Lee, Lawrence Soon-U; Cove, Matthew; Ling, Li Min; Kwa, Andrea Layhoon 分享 收藏
The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b Bodyak, Natalya D.; Mosher, Rebecca; Yurkovetskiy, Aleksandr, V; Yin, Mao; Bu, Charlie; Conlon, Patrick R.; Demady, Damon R.; DeVit, Michael J.; Gumerov, Dmitry R.; Gurijala, Venu R.; Lee, Winnie; McGillicuddy, Dennis; Park, Peter U.; Poling, Laura L.; Protopova, Marina; Qin, LiuLiang; Stevenson, Cheri A.; Ter-Ovanesyan, Elena; Uttard, Alex; Xiao, Dongmei; Xu, Jian; Xu, Ling; Bergstrom, Donald A.; Lowinger, Timothy B. 分享 收藏
Elimination of Extracellular Adenosine Triphosphate for the Rapid Prediction of Quantitative Plate Counts in 24 h Time-Kill Studies against Carbapenem-Resistant Gram-Negative Bacteria Cai, Yiying; Ng, Jonathan J.; Leck, Hui; Teo, Jocelyn Q.; Goh, Jia-Xuan; Lee, Winnie; Koh, Tse-Hsien; Tan, Thuan-Tong; Lim, Tze-Peng; Kwa, Andrea L. 分享 收藏
XMT-1592, a site-specific Dolasynthen-based NaPi2b-targeted antibody-drug conjugate for the treatment of ovarian cancer and lung adenocarcinoma Fessler, Shawn; Dirksen, Anouk; Collins, Scott D.; Xu, Ling; Lee, Winnie; Wang, Jason; Eydelloth, Ron; Ter-Ovanesyen, Elena; Zurita, Jeffrey; Ditty, Elizabeth; Nehilla, Barrett; Clardy, Susan; Carter, Tyler; Avocetien, Kenneth; Nazzaro, Mark; Le, Nam; Catcott, Kalli C.; Uttard, Alex; Du, Bingfan; Chin, Chen-Ni; Mosher, Rebecca; Slocum, Kelly; Qin, Liuliang; Lee, David; Toader, Dorin; Damelin, Marc; Lowinger, Timothy B. 分享 收藏
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Determining the Development of Persisters in Extensively Drug-Resistant Acinetobacter baumannii upon Exposure to Polymyxin B-Based Antibiotic Combinations Using Flow Cytometry Wong, Fiona Hui-Sian; Cai, Yiying; Leck, Hui; Lim, Tze-Peng; Teo, Jocelyn Qi-Min; Lee, Winnie; Koh, Tse Hsien; Tan, Thuan Tong; Tan, Kar Wai; Kwa, Andrea Lay-Hoon 分享 收藏
Dolasynthen-a novel, homogeneous Auristatin F hydroxypropyl amide antibody-drug conjugate platform Toader, Dorin; Damelin, Marc; Dirksen, Anouk; Fesler, Shawn P.; Collins, Scott D.; Nehilla, Barrett J.; Xu, Jian; Xu, Ling; Cattcott, Kalli C.; Uttard, Alex; Lee, Winnie; Clardy, Susan; Stevenson, Cheri A.; Qin, LiuLiang; Conlon, Patrick R.; Kozytska, Mariya V.; Chin, Chen-Ni; Lee, David H.; Lowinger, Timothy B. 分享 收藏
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Candidemia in a major regional tertiary referral hospital - epidemiology, practice patterns and outcomes (vol 6, 27, 2017) Teo, Jocelyn Qi-Min; Candra, Samuel Rocky; Lee, Shannon Jing-Yi; Chia, Shannon Yu-Hng; Leck, Hui; Tan, Ai-Ling; Neo, Hui-Peng; Leow, Kenneth Wei-Liang; Cai, Yiying; Ee, Pui Lai Rachel; Lim, Tze-Peng; Lee, Winnie; Kwa, Lay-Hoon 分享 收藏
Rapid Antibiotic Combination Testing for Carbapenem-Resistant Gram-Negative Bacteria within Six Hours Using ATP Bioluminescence Cai, Yiying; Seah, Celene L.; Leck, Hui; Lim, Tze-Peng; Teo, Jocelyn Q.; Lee, Winnie; Tan, Thuan-Tong; Koh, Tse-Hsien; Ee, Pui Lai Rachel; Kwa, Andrea L. 分享 收藏
EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity E7046对EP4的拮抗作用可减轻骨髓免疫抑制,并与减少Treg的IL-2-Diphtheria毒素融合蛋白协同恢复抗肿瘤免疫 Albu, Diana I.; Wang, Zichun; Huang, Kuan-Chun; Wu, Jiayi; Twine, Natalie; Leacu, Sarah; Ingersoll, Christy; Parent, Lana; Lee, Winnie; Liu, Diana; Wright-Michaud, Renee; Kumar, Namita; Kuznetsov, Galina; Chen, Qian; Zheng, Wanjun; Nomoto, Kenichi; Woodall-Jappe, Mary; Bao, Xingfeng 分享 收藏
Prevalence of Healthcare-Associated Infections and Antimicrobial Use Among Adult Inpatients in Singapore Acute-Care Hospitals: Results From the First National Point Prevalence Survey Cai, Yiying; Venkatachalam, Indumathi; Tee, Nancy W.; Tan, Thean Yen; Kurup, Asok; Wong, Sin Yew; Low, Chian Yong; Wang, Yang; Lee, Winnie; Liew, Yi Xin; Ang, Brenda; Lye, David C.; Chow, Angela; Ling, Moi Lin; Oh, Helen M.; Cuvin, Cassandra A.; Ooi, Say Tat; Pada, Surinder K.; Lim, Chong Hee; Tan, Jack Wei Chieh; Chew, Kean Lee; Nguyen, Van Hai; Fisher, Dale A.; Goossens, Herman; Kwa, Andrea L.; Tambyah, Paul A.; Hsu, Li Yang; Marimuthu, Kalisvar 分享 收藏
Candidemia in a major regional tertiary referral hospital - epidemiology, practice patterns and outcomes Teo, Jocelyn Qi-Min; Candra, Samuel Rocky; Lee, Shannon Jing-Yi; Chia, Shannon Yu-Hng; Leck, Hui; Tan, Ai-Ling; Neo, Hui-Peng; Leow, Kenneth Wei-Liang; Cai, Yiying; Ee, Rachel Pui-Lai; Lim, Tze-Peng; Lee, Winnie; Kwa, Andrea Lay-Hoon 分享 收藏
Evaluating Polymyxin B-Based Combinations against Carbapenem-Resistant Escherichia coli in Time-Kill Studies and in a Hollow-Fiber Infection Model Cai, Yiying; Lim, Tze-Peng; Teo, Jocelyn Qi-Min; Sasikala, Suranthran; Chan, Eric Chun Yong; Hong, Yan Jun; Lee, Winnie; Tan, Thean Yen; Tan, Thuan Tong; Koh, Tse Hsien; Hsu, Li Yang; Kwa, Andrea L. 分享 收藏
In Vitro Activity of Polymyxin B in Combination with Various Antibiotics against Extensively Drug-Resistant Enterobacter cloacae with Decreased Susceptibility to Polymyxin B Cai, Yiying; Lim, Tze-Peng; Teo, Jocelyn; Sasikala, Suranthran; Lee, Winnie; Hong, Yanjun; Chan, Eric Chun Yong; Tan, Thean Yen; Tan, Thuan-Tong; Koh, Tse Hsien; Hsu, Li Yang; Kwa, Andrea L. 分享 收藏
Discovery and preclinical development of a highly potent NaPi2b-targeted antibody -drug conjugate (ADC) with significant activity in patient -derived non -small cell lung cancer (NSCLC) xenograft models Bodyak, Natalya; Yurkovetskiy, Alex; Yin, Mao; Gumerov, Dmitry; Bollu, Reddy; Conlon, Patrick; Gurijala, Venu R.; McGillicuddy, Dennis; Stevenson, Cheri; Ter-Ovanesyan, Elena; Park, Peter U.; Poling, Laura; Lee, Winnie; Devit, Michael; Xiao, Dongmei; Qin, LiuLiang; Lowinger, Timothy B.; Bergstrom, Donald A. 分享 收藏
Optimization of lead antibody selection for XMT-1522, a novel, highly potent HER2-targeted antibody-drug conjugate (ADC) Bodyak, Natasha; Yurkovetskiy, Alex; Gumerov, Dmitry R.; Xiao, Dongmei; Thomas, Joshua D. Thomad D.; Poling, Laura L.; Qin, LiuLiang; Yin, Mao; DeVit, Michael J.; Park, Peter U.; Lee, Winnie; Prinz, Bianka; Bergstrom, Donald A.; Lowinger, Timothy B. 分享 收藏
Clinical Efficacy of Polymyxin Monotherapy versus Nonvalidated Polymyxin Combination Therapy versus Validated Polymyxin Combination Therapy in Extensively Drug-Resistant Gram-Negative Bacillus Infections Cai, Bingxuan; Cai, Yiying; Liew, Yi Xin; Chua, Nathalie Grace; Teo, Jocelyn Qi-Min; Lim, Tze-Peng; Kurup, Asok; Ee, Pui Lai Rachel; Thuan Tong Tan; Lee, Winnie; Kwa, Andrea Lay-Hoon 分享 收藏