Eric W.F.W. Alton - Publications, H-index & Citations

Eric W.F.W. Alton

Imperial College London

63H指数

475论文数

1.3W被引数

收录论文 158

发表时间

Intranasal delivery of mRNA expressing newly identified Acinetobacter baumannii antigens protects against bacterial lung disease 表达新鉴定的鲍曼不动杆菌抗原的mRNA的鼻内递送可预防细菌性肺病

npj Vaccines

IF6.5

2025-07-04

OAAI

Sophie L. Higham; Ziyin Wang; Valarmathy Murugaiah; Jihye Song; Chubicka Thomas; Houze Zhang; Uta Griesenbach; Eric W. F. W. Alton; Luke A. Granger; Andrea Flores Esparza; Beatriz Dias Barbieri; Paul G. Hitchen; Paul Kellam; Robin J. Shattock; Shiranee Sriskandan; Stephen T. Reece; John S. Tregoning

Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis 在囊性纤维化小鼠模型中，NFAT和NFκB信号通路的增强促进了宿主对烟曲霉（Aspergillus fumigatus）的过度炎症反应表型。

PLOS PATHOGENS

IF4.9

2025-02-04

OAAI

Bercusson, Amelia; Williams, Thomas J.; Simmonds, Nicholas J.; Alton, Eric W. F. W.; Shah, Anand; Warris, Adilia; Armstrong-James, Darius

Fixing lung health in the UK: accelerating respiratory research and innovation

THORAX

IF7.7

2024-08-03

PREAI

Routley, Cheryl; Walker, Samantha; Alton, Eric W. F. W.; Hall, Ian P.

Nasal potential difference (NPD) and extended genetic analysis improve classification of CF and CFTR-related disorders: outcomes from a national difficult CF diagnosis (DCFD) service

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-27

PREAI

Agaoglu, Elif S.; Morris-Rosendahl, Deborah J.; Waller, Michael D.; Quinn, Ellie; Banya, Winston; Felton, Imogen; Robinson, Rachel; Alton, Eric W.; Davies, Jane C.; Simmonds, Nicholas J.

Lytic Bacteriophage Is a Promising Adjunct to Common Antibiotics across Cystic Fibrosis Clinical Strains and Culture Models of Pseudomonas aeruginosa Infection

ANTIBIOTICS-BASEL

IF4.6

2023-03-16

OAAI

Martin, Isaac; Morales, Sandra; Alton, Eric W. F. W.; Davies, Jane C.

The feasibility of home monitoring of young people with cystic fibrosis: Results from CLIMB-CF

JOURNAL OF CYSTIC FIBROSIS

IF6

2022-01-01

OAAI

Edmondson, C.; Westrupp, N.; Seddon, P.; Olden, C.; Wallis, C.; Dawson, C.; Brodlie, M.; Baxter, F.; McCormick, J.; MacFarlane, S.; Rice, D.; Macleod, A.; Brooker, R.; Connon, M.; Ghayyda, S.; Blaikie, L.; Thursfield, R.; Brown, L.; Price, A.; Fleischer, E.; Itterman, J.; Hughes, D.; Barrett, P.; Surette, M.; Donnelly, C.; Mateos-Corral, D.; Padley, G.; Wallenburg, J.; Brownlee, K.; Alton, E. W. F. W.; Bush, A.; Davies, J. C.

Transepithelial nasal potential difference in patients with, and at risk of acute respiratory distress syndrome

THORAX

IF7.7

2021-04-22

OAAI

Mac Sweeney, Rob; Reddy, Kiran; Davies, Jane C.; Parker, Mike; Kelly, Barry; Elborn, J. Stuart; Conlon, John; Verghis, Rejina M.; Calfee, Carolyn S.; Matthay, Michael A.; Alton, Eric W. F. W.; McAuley, Daniel F.

Variability in Bacteriophage and Antibiotic Sensitivity in Serial Pseudomonas aeruginosa Isolates from Cystic Fibrosis Airway Cultures over 12 Months

MICROORGANISMS

IF4.2

2021-03-22

OAAI

Martin, Isaac; Kenna, Dervla T. D.; Morales, Sandra; Alton, Eric W. F. W.; Davies, Jane C.

LOW LEVELS OF LENTIVIRUS-MEDIATED CFTR GENE TRANSFER ARE SUFFICIENT TO GENERATE ION TRANSPORT CORRECTION IN AIR-LIQUID INTERFACE CULTURES FROM CYSTIC FIBROSIS PATIENTS

THORAX

IF7.7

2021-01-21

PREAI

Sergijenko, A.; Moiseenko, A.; Pineault, K.; Nafchi, N. A. M.; Chan, M.; Gamlen, T.; Gill, D. R.; Hyde, S. C.; Kreuz, S.; Griesenbach, U.; Alton, E. W. F. W.

QUANTIFICATION OF MRNA AND PROTEIN FROM SINGLE CELLS FOR CYSTIC FIBROSIS GENE THERAPY

THORAX

IF7.7

2021-01-21

PREAI

Sinadinos, A. J.; Sergijenko, A.; Saleh, A. D.; Nafchi, N. A. M.; Hickmott, J. W.; Gamlen, T.; Gill, D. R.; Hyde, S. C.; Alton, E. W. F. W.; Griesenbach, U.

DEVELOPMENT OF PROTOCOLS FOR MOUSE GLP-TOXICOLOGY STUDIES

THORAX

IF7.7

2021-01-21

PREAI

Sinadinos, A.; Sergijenko, A.; Meng, C.; Gamlen, T.; Hyde, S.; Gill, D. R.; Griesenbach, U.; Alton, E. W. F. W.

TOWARDS A FIRST-IN-HUMAN TRIAL WITH A PSEUDOTYPED LENTIVIRUS

THORAX

IF7.7

2021-01-21

PREAI

Alton, E. W. F. W.; Boyd, A. C.; Davies, J. C.; Gill, D. R.; Griesenbach, U.; Harman, T. E.; Hyde, S. C.; McLachlan, G.

Whole-Gene Sequencing of CFTR Reveals a High Prevalence of the Intronic Variant c.3874-4522A>G in Cystic Fibrosis

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2020-06-01

OAAI

Morris-Rosendahl, Deborah J.; Edwards, Matthew; McDonnell, Melissa J.; John, Shibu; Alton, Eric W. F. W.; Davies, Jane C.; Simmonds, Nicholas J.

Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis

JOURNAL OF CYSTIC FIBROSIS

IF6

2020-01-01

OAAI

Turnbull, Andrew R.; Pyle, Chloe J.; Patel, Dhiren F.; Jackson, Patricia L.; Hilliard, Tom N.; Regamey, Nicolas; Tan, Hui-Leng; Brown, Sarah; Thursfield, Rebecca; Short, Christopher; Mc Fie, Megan; Alton, Eric W. F. W.; Gaggar, Amit; Blalock, J. Edwin; Lloyd, Clare M.; Bush, Andrew; Dayies, Jane C.; Snelgrove, Robert J.

PEAK NASAL INSPIRATORY FLOW AND NASAL CYTOKINES ARE USEFUL BIOMARKERS OF NASAL INFLAMMATION IN CYSTIC FIBROSIS GENE THERAPY

THORAX

IF7.7

2019-11-12

PREAI

Saleh, A. D.; Durham, S. R.; Shamji, M. H.; Griesenbach, U.; Alton, E. W. F. W.

DELIVERING THE 100,000 GENOMES PROJECT TO ESTABLISH THE FUNCTIONAL ROLE OF DNA SEQUENCE VARIANTS IN RESPIRATORY RARE DISEASES

THORAX

IF7.7

2019-11-12

PREAI

Shovlin, C. L.; Morris-Rosendahl, D. J.; Copeland, F.; De Soyza, A.; Hogg, C.; Jenkins, G.; Marciniak, S. J.; Lovett, M.; Moffatt, M. F.; Cookson, W. O. C.; Alikian, M.; Hasan, S.; Slade, R.; Xiao, S.; Boardman-Pretty, F.; Brown, D.; Caulfield, M.; Devereau, A.; Fowler, T.; McDonagh, E.; Scott, R.; Thomas, E. R. A.; Alton, E. W. F. W.

Training dogs to differentiate Pseudomonas aeruginosa from other cystic fibrosis bacterial pathogens: not to be sniffed at?

EUROPEAN RESPIRATORY JOURNAL

IF21

2019-08-14

OAAI

Davies, Jane C.; Alton, Eric; Simbo, Ameze; Murphy, Ronan; Seth, Ishani; Williams, Kate; Somerville, Mark; Jolly, Libby; Morant, Steve; Guest, Claire

LENTIVIRUS GM-CSF GENE THERAPY AMELIORATES AUTOIMMUNE PULMONARY ALVEOLAR PROTEINOSIS

THORAX

IF7.7

2018-12-01

PREAI

Lund-Palau, H.; Meng, C.; Pilou, A.; Atsumi, N.; Bhargava, A.; Chan, M.; Byrne, A.; Pringle, I.; Ashworth, R.; Gill, D.; Hyde, S.; Morgan, C.; Alton, E.; Griesenbach, U.

Children with cystic fibrosis demonstrate no respiratory immunological, infective or physiological, consequences of vitamin D deficiency

JOURNAL OF CYSTIC FIBROSIS

IF6

2018-09-01

OAAI

Thursfield, Rebecca M.; Naderi, Khayam; Leaver, Neil; Rosenthal, Mark; Alton, Eric W. F. W.; Bush, Andrew; Davies, Jane C.

Metabolic Phenotyping and Strain Characterisation of Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients Using Rapid Evaporative Ionisation Mass Spectrometry

SCIENTIFIC REPORTS

IF3.9

2018-07-19

OAAI

Bardin, Emmanuelle E.; Cameron, Simon J. S.; Perdones-Montero, Alvaro; Hardiman, Kate; Bolt, Frances; Alton, Eric W. F. W.; Bush, Andrew; Davies, Jane C.; Takats, Zoltan

研究方向