未登录A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer用于胰腺癌生物标志物发现的循环细胞外囊泡的大规模蛋白质组学资源
Bockorny, Bruno; Muthuswamy, Lakshmi; Huang, Ling; Hadisurya, Marco; Lim, Christine Maria; Tsai, Leo L.; Gill, Ritu R.; Wei, Jesse L.; Bullock, Andrea J.; Grossman, Joseph E.; Besaw, Robert J.; Narasimhan, Supraja; Tao, Weiguo Andy; Perea, Sofia; Sawhney, Mandeep S.; Freedman, Steven D.; Hildago, Manuel; Iliuk, Anton; Muthuswamy, Senthil K. .png)
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收藏Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer (11 Nov, 10.1038/s41588-024-01958-6, 2024)Brca1单倍体不足在遗传性乳腺癌小鼠模型中促进早期肿瘤发作和表观遗传改变 (11月11日，10.1038/s41588-024-01958-6，2024)Li, Carman Man-Chung; Cordes, Alyssa; Oliphant, Michael U. J.; Quinn, S. Aidan; Thomas, Mayura; Selfors, Laura M.; Silvestri, Francesca; Girnius, Nomeda; Rinaldi, Gianmarco; Zoeller, Jason J.; Shapiro, Hana; Tsiobikas, Christina; Gupta, Kushali P.; Pathania, Shailja; Regev, Aviv; Kadoch, Cigall; Muthuswamy, Senthil K.; Brugge, Joan S. 分享 收藏 Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancerBrca1单倍不足可促进遗传性乳腺癌小鼠模型的早期肿瘤发作和表观遗传改变Li, Carman Man-Chung; Cordes, Alyssa; Oliphant, Michael U. J.; Quinn, S. Aidan; Thomas, Mayura; Selfors, Laura M.; Silvestri, Francesca; Girnius, Nomeda; Rinaldi, Gianmarco; Zoeller, Jason J.; Shapiro, Hana; Tsiobikas, Christina; Gupta, Kushali P.; Pathania, Shailja; Regev, Aviv; Kadoch, S. Cigall; Muthuswamy, Senthil K.; Brugge, Joan S. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Requirement for both Shc and phosphatidylinositol 3′ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesisWebster, MA; Hutchinson, JN; Rauh, MJ; Muthuswamy, SK; Anton, M; Tortorice, CG; Cardiff, RD; Graham, FL; Hassell, JA; Muller, WJ 分享 收藏 分享 收藏 Expression Profiling during Mammary Epithelial Cell Three-Dimensional Morphogenesis Identifies PTPRO as a Novel Regulator of Morphogenesis and ErbB2-Mediated TransformationYu, Min; Lin, Guang; Arshadi, Niloofar; Kalatskaya, Irina; Xue, Bin; Haider, Syed; Nguyen, Francis; Boutros, Paul C.; Elson, Ari; Muthuswamy, Lakshmi B.; Tonks, Nicholas K.; Muthuswamy, Senthil K. 分享 收藏 Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMTPaul, Indranil; Bolzan, Dante; Youssef, Ahmed; Gagnon, Keith A.; Hook, Heather; Karemore, Gopal; Oliphant, Michael U. J.; Lin, Weiwei; Liu, Qian; Phanse, Sadhna; White, Carl; Padhorny, Dzmitry; Kotelnikov, Sergei; Chen, Christopher S.; Hu, Pingzhao; Denis, Gerald V.; Kozakov, Dima; Raught, Brian; Siggers, Trevor; Wuchty, Stefan; Muthuswamy, Senthil K.; Emili, Andrew 分享 收藏 分享 收藏 Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER plus breast cancerSaito, Yasuhiro; Matsuda, Shiori; Ohnishi, Naomi; Endo, Keiko; Ashitani, Sanae; Ohishi, Maki; Ueno, Ayano; Tomita, Masaru; Ueda, Koji; Soga, Tomoyoshi; Muthuswamy, Senthil K. 分享 收藏 Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors全基因组合成致死筛选揭示了新型CAIX-NFS1/xCT轴作为低氧实体瘤的可靶向脆弱性Chafe, Shawn C.; Vizeacoumar, Frederick S.; Venkateswaran, Geetha; Nemirovsky, Oksana; Awrey, Shannon; Brown, Wells S.; McDonald, Paul C.; Carta, Fabrizio; Metcalfe, Andrew; Karasinska, Joanna M.; Huang, Ling; Muthuswamy, Senthil K.; Schaeffer, David F.; Renouf, Daniel J.; Supuran, Claudiu T.; Vizeacoumar, Franco J.; Dedhar, Shoukat 分享 收藏 Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoidsHuang, Ling; Desai, Ridhdhi; Conrad, Daniel N.; Leite, Nayara C.; Akshinthala, Dipikaa; Lim, Christine Maria; Gonzalez, Raul; Muthuswamy, Lakshmi B.; Gartner, Zev; Muthuswamy, Senthil K. 分享 收藏 Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancerDadali, Tulin; Diers, Anne R.; Kazerounian, Shiva; Muthuswamy, Senthil K.; Awate, Pallavi; Ng, Ryan; Mogre, Saie; Spencer, Carrie; Krumova, Katerina; Rockwell, Hannah E.; McDaniel, Justice; Chen, Emily Y.; Gao, Fei; Diedrich, Karl T.; Vemulapalli, Vijetha; Rodrigues, Leonardo O.; Akmaev, Viatcheslav R.; Thapa, Khampaseuth; Hidalgo, Manuel; Bose, Arindam; Vishnudas, Vivek K.; Moser, A. James; Granger, Elder; Kiebish, Michael A.; Gesta, Stephane; Narain, Niven R.; Sarangarajan, Rangaprasad 分享 收藏 PDX-derived organoids model in vivo drug response and secrete biomarkersHuang, Ling; Bockorny, Bruno; Paul, Indranil; Akshinthala, Dipikaa; Frappart, Pierre-Oliver; Gandarilla, Omar; Bose, Arindam; Sanchez-Gonzalez, Veronica; Rouse, Emily E.; Lehoux, Sylvain D.; Pandell, Nicole; Lim, Christine M.; Clohessy, John G.; Grossman, Joseph; Gonzalez, Raul; Del Pino, Sofia Perea; Daaboul, George; Sawhney, Mandeep S.; Freedman, Steven D.; Kleger, Alexander; Cummings, Richard D.; Emili, Andrew; Muthuswamy, Lakshmi B.; Hidalgo, Manuel; Muthuswamy, Senthil K. 分享 收藏 Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold (vol 63, pg 7817, 2020)Ferguson, Fleur M.; Liu, Yan; Harshbarger, Wayne; Huang, Ling; Wang, Jinhua; Deng, Xianming; Capuzzi, Stephen J.; Muratov, Eugene N.; Tropsha, Alexander; Muthuswamy, Senthil; Westover, Kenneth D.; Gray, Nathanael S. 分享 收藏 Discovery of New Targets to Control Metastasis in Pancreatic Cancer by Single-cell Transcriptomics Analysis of Circulating Tumor CellsDimitrov-Markov, Spas; Perales-Paton, Javier; Bockorny, Bruno; Dopazo, Ana; Munoz, Manuel; Banos, Natalia; Bonilla, Victoria; Menendez, Camino; Duran, Yolanda; Huang, Ling; Perea, Sofia; Muthuswamy, Senthil K.; Al-Shahrour, Fatima; Lopez-Casas, Pedro P.; Hidalgo, Manuel 分享 收藏 Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one ScaffoldFerguson, Fleur M.; Liu, Yan; Harshbarger, Wayne; Huang, Ling; Wang, Jinhua; Deng, Xianming; Capuzzi, Stephen J.; Muratov, Eugene N.; Tropsha, Alexander; Muthuswamy, Senthil; Westover, Kenneth D.; Gray, Nathanael S. 分享 收藏 
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