未登录 Central Nervous System Biodistribution and Pharmacokinetics of Radiolabeled Tofersen in Rodents, Nonhuman Primates, and Humans 放射性标记托夫森在啮齿动物、非人灵长类和人体中的中枢神经系统生物分布和药代动力学 Cook, Brendon E.; McLaren, Donald G.; Sullivan, Jenna M.; El Fakhri, Georges; Yokell, Daniel L.; Freeman, Mason W.; Currier, Nicolas; Oestergaard, Michael E.; Dobson, Howard; Hesterman, Jacob; Salem, Nicolas; Nestorov, Ivan; Monine, Michael; Martarello, Laurent; Evans, Karleyton C.; Fradette, Stephanie; Ferguson, Toby A.; Graham, Danielle; Passamonti, Luca 分享 收藏
Actinium-225-PSMA-Trillium (BAY 3563254): Preclinical evaluation and clinical imaging study of a novel 225Ac-labeled PSMA-targeting small molecule triad for the treatment of mCRPC Zitzmann-Kolbe, Sabine; Hesterman, Jacob; Cole, Patricia E.; Salem, Nicolas; Papple, Alex; Jeffers, Michael; Koca, Goekben; Poethko, Thorsten; Dostalek, Miroslav; Hillier, Shawn; Babich, John W. 分享 收藏
Application of Aligned-UMAP to longitudinal biomedical studies Dadu, Anant; Satone, Vipul K.; Kaur, Rachneet; Koretsky, Mathew J.; Iwaki, Hirotaka; Qi, Yue A.; Ramos, Daniel M.; Avants, Brian; Hesterman, Jacob; Gunn, Roger; Cookson, Mark R.; Ward, Michael E.; Singleton, Andrew B.; Campbell, Roy H.; Nalls, Mike A.; Faghri, Faraz 分享 收藏
Quanticell, a novel histopathology technology for visualization and quantitation of membrane PSMA demonstrated in cell lines and clinical tissue Dimant, Hemi; Gandhi, Ankit; Maker, Micheal; Markman, Adam; Reinhardt, Jeanette; Collins, Stefan; Hesterman, Jacob; Krueger, Joseph; Bloom, Kenneth; Bailis, Julie; Juan, Gloria 分享 收藏
Convective forces increase rostral delivery of intrathecal radiotracers and antisense oligonucleotides in the cynomolgus monkey nervous system Sullivan, Jenna M.; Mazur, Curt; Wolf, Daniel A.; Horky, Laura; Currier, Nicolas; Fitzsimmons, Bethany; Hesterman, Jacob; Pauplis, Rachel; Haller, Scott; Powers, Berit; Tayefeh, Leighla; DeBrosse-Serra, Bea; Hoppin, Jack; Kordasiewicz, Holly; Swayze, Eric E.; Verma, Ajay 分享 收藏
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Neurophysiological Biomarkers of Parkinson?s Disease Waninger, Shani; Berka, Chris; Karic, Marija Stevanovic; Korszen, Stephanie; Mozley, P. David; Henchcliffe, Claire; Kang, Yeona; Hesterman, Jacob; Mangoubi, Tomer; Verma, Ajay 分享 收藏
Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging Mazur, Curt; Powers, Berit; Zasadny, Kenneth; Sullivan, Jenna M.; Dimant, Hemi; Kamme, Fredrik; Hesterman, Jacob; Matson, John; Oestergaard, Michael; Seaman, Marc; Holt, Robert W.; Qutaish, Mohammed; Polyak, Ildiko; Coelho, Richard; Gottumukkala, Vijay; Gaut, Carolynn M.; Berridge, Marc; Albargothy, Nazira J.; Kelly, Louise; Carare, Roxana O.; Hoppin, Jack; Kordasiewicz, Holly; Swayze, Eric E.; Verma, Ajay 分享 收藏
Treatment of internuclear ophthalmoparesis in multiple sclerosis with fampridine: A randomized double-blind, placebo-controlled cross-over trial Kanhai, Kawita M. S.; Bijvank, Jenny A. Nij; Wagenaar, Yorick L.; Klaassen, Erica S.; Lim, KyoungSoo; Bergheanu, Sandrin C.; Petzold, Axel; Verma, Ajay; Hesterman, Jacob; Wattjes, Mike P.; Uitdehaag, Bernard M. J.; van Rijn, Laurentius J.; Groeneveld, Geert Jan 分享 收藏
Dual-Isotope Cryoimaging Quantitative Autoradiography: Investigating Antibody-Drug Conjugate Distribution and Payload Delivery Through Imaging Ilovich, Ohad; Qutaish, Mohammed; Hesterman, Jacob Y.; Orcutt, Kelly; Hoppin, Jack; Polyak, Ildiko; Seaman, Marc; Abu-Yousif, Adnan O.; Cvet, Donna; Bradley, Daniel P. 分享 收藏
Sclerostin and DKK1 Inhibition Preserves and Augments Alveolar Bone Volume and Architecture in Rats with Alveolar Bone Loss Liu, M.; Kurimoto, P.; Zhang, J.; Niu, Q. T.; Stolina, M.; Dechow, P. C.; Feng, J. Q.; Hesterman, J.; Silva, M. D.; Ominsky, M. S.; Richards, W. G.; Ke, H.; Kostenuik, P. J. 分享 收藏
The Expansion of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva Is Activin A-Dependent Upadhyay, Jaymin; Xie, LiQin; Huang, Lily; Das, Nanditha; Stewart, Rachel C.; Lyon, Morgan C.; Palmer, Keryn; Rajamani, Saathyaki; Graul, Chris; Lobo, Merryl; Wellman, Tyler J.; Soares, Edward J.; Silva, Matthew D.; Hesterman, Jacob; Wang, Lili; Wen, Xialing; Qian, Xiaobing; Nannuru, Kalyan; Idone, Vincent; Murphy, Andrew J.; Economides, Aris N.; Hatsell, Sarah J. 分享 收藏
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A dual-isotope 3D cryo-imaging quantitative autoradiography (CIQA) method for simultaneous and quantitative assessment of both antibody and drug conjugate tumor distribution and kinetics Ilovich, Ohad; Qutaish, Mohammed; Hesterman, Jacob; Orcutt, Kelly; Hoppin, Jack; Polyak, Ildiko; Seaman, Marc; Czarnecki, Paige; Gottumukkala, Vijay; Plesescu, Mihaela; Yardibi, Ozlem; Bradley, Daniel 分享 收藏
Micro-Cr imaging: Developing criteria for examining fetal skeletons in regulatory developmental toxicology studies - A workshop report Solomon, Howard M.; Makris, Susan L.; Alsaid, Hasan; Bermudez, Oscar; Beyer, Bruce K.; Chen, Antong; Chen, Connie L.; Chen, Zhou; Chmielewski, Gary; DeLise, Anthony M.; de Schaepdrijver, Luc; Dogdas, Belma; French, Julian; Harrouk, Wafa; Helfgott, Jonathan; Henkelman, R. Mark; Hesterman, Jacob; Hew, Kok-Wah; Hoberman, Alan; Lo, Cecilia W.; McDougal, Andrew; Minck, Daniel R.; Scott, Lelia; Stewart, Jane; Sutherland, Vicki; Tatiparthi, Arun K.; Winkelmann, Christopher T.; Wise, L. David; Wood, Sandra L.; Ying, Xiaoyou 分享 收藏
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In vitro and in vivo investigation of the novel, first-in-class, Guanylyl Cyclase C (GCC) targeted 68Ga labeled heat stable peptide MLN6907 ([68Ga]MLN6907) for tumor imaging Cvet, Donna; Robertson, Robert; Saylor, Melissa; Terkelsen, Jennifer; Yardibi, Ozlem; Borland, Maria; Salem, Nicolas; Veiby, Petter; Sells, Todd; Carsillo, Mary; Yang, Johnny; Teng, Shu-Wen; Hoppin, John; Orcutt, Kelly; Hesterman, Jacob; Norenberg, Jeffery; Anderson, Tamara; Schulz, Mike; Ruscowski, Mary; Berridge, Marc; Mather, Steven; Bradley, Daniel P. 分享 收藏
PET/CT clinical protocol design for the novel, first in class 68Ga labeled guanylyl cyclase C targeted peptide MLN6907 ([68Ga]MLN6907) Hesterman, Jacob Y.; Orcutt, Kelly D.; Yardibi, Ozlem; Mettetal, Jerome T.; Teng, Shu-Wen; Cvet, Donna; Hoppin, Jack; Kalebic, Thea; Bradley, Daniel P. 分享 收藏
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