未登录 Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study Puurunen, Marja K.; Vockley, Jerry; Searle, Shawn L.; Sacharow, Stephanie J.; Phillips, John A., III; Denney, William S.; Goodlett, Benjamin D.; Wagner, David A.; Blankstein, Larry; Castillo, Mary J.; Charbonneau, Mark R.; Isabella, Vincent M.; Sethuraman, Vasu V.; Riese, Richard J.; Kurtz, Caroline B.; Brennan, Aoife M. 分享 收藏
Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial Strain in Hereditary Transthyretin Amyloidosis The APOLLO Study Minamisawa, Masatoshi; Claggett, Brian; Adams, David; Kristen, Arnt V.; Merlini, Giampaolo; Slama, Michel S.; Dispenzieri, Angela; Shah, Amil M.; Falk, Rodney H.; Karsten, Verena; Sweetser, Marianne T.; Chen, Jihong; Riese, Richard; Vest, John; Solomon, Scott D. 分享 收藏
Long-term safety of tofacitinib for the treatment of rheumatoid arthritis up to 8.5 years: integrated analysis of data from the global clinical trials Cohen, Stanley B.; Tanaka, Yoshiya; Mariette, Xavier; Curtis, Jeffrey R.; Lee, Eun Bong; Nash, Peter; Winthrop, Kevin L.; Charles-Schoeman, Christina; Thirunavukkarasu, Krishan; DeMasi, Ryan; Geier, Jamie; Kwok, Kenneth; Wang, Lisy; Riese, Richard; Wollenhaupt, Juergen 分享 收藏
Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis Winthrop, K. L.; Park, S-H; Gul, A.; Cardiel, M. H.; Gomez-Reino, J. J.; Tanaka, Y.; Kwok, K.; Lukic, T.; Mortensen, E.; Ponce de Leon, D.; Riese, R.; Valdez, H. 分享 收藏
Tofacitinib, an oral Janus kinase inhibitor: analysis of malignancies across the rheumatoid arthritis clinical development programme 口服Janus激酶抑制剂Tofacitinib: 类风湿关节炎临床开发计划中的恶性肿瘤分析 Curtis, Jeffrey R.; Lee, Eun Bong; Kaplan, Irina V.; Kwok, Kenneth; Geier, Jamie; Benda, Birgitta; Soma, Koshika; Wang, Lisy; Riese, Richard 分享 收藏
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Potential Mechanisms Leading to the Abnormal Lipid Profile in Patients With Rheumatoid Arthritis Versus Healthy Volunteers and Reversal by Tofacitinib 导致类风湿关节炎患者与健康志愿者血脂异常的潜在机制以及托法替尼的逆转 Charles-Schoeman, Christina; Fleischmann, Roy; Davignon, Jean; Schwartz, Howard; Turner, Scott M.; Beysen, Carine; Milad, Mark; Hellerstein, Marc K.; Luo, Zhen; Kaplan, Irina V.; Riese, Richard; Zuckerman, Andrea; McInnes, Iain B. 分享 收藏
Analysis of Infections and All-Cause Mortality in Phase II, Phase III, and Long-Term Extension Studies of Tofacitinib in Patients With Rheumatoid Arthritis Cohen, Stanley; Radominski, Sebastiao C.; Gomez-Reino, Juan J.; Wang, Lisy; Krishnaswami, Sriram; Wood, Susan P.; Soma, Koshika; Nduaka, Chudi I.; Kwok, Kenneth; Valdez, Hernan; Benda, Birgitta; Riese, Richard 分享 收藏
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INTEGRATED SAFETY ANALYSIS OF TOFACITINIB IN RA CLINICAL TRIALS WITH A CUMULATIVE EXPOSURE OF 12,664 PATIENT-YEARS Cohen, S.; Tanaka, Y.; Mariette, X.; Curtis, J.; Kwok, K.; Lee, E.; Nash, P.; Winthrop, K.; Charles-Schoeman, C.; Thirunavukkarasu, K.; Anisfeld, A.; Wang, L.; Riese, R.; Wollenhaupt, J. 分享 收藏
TOFACITINIB, AN ORAL JANUS KINASE INHIBITOR: ANALYSIS OF MALIGNANCIES ACROSS THE RHEUMATOID ARTHRITIS CLINICAL PROGRAMME Mariette, X.; Curtis, J.; Lee, E.; Benda, B.; Kaplan, I.; Soma, K.; Kwok, K.; Geier, J.; Wang, L.; Riese, R. 分享 收藏
Safety and Efficacy of Tofacitinib, an Oral Janus Kinase Inhibitor, for the Treatment of Rheumatoid Arthritis in Open-label, Longterm Extension Studies 口服Janus激酶抑制剂托法替尼治疗类风湿关节炎的安全性和有效性的开放标签，长期扩展研究 Wollenhaupt, Juergen; Silverfield, Joel; Lee, Eun Bong; Curtis, Jeffrey R.; Wood, Susan P.; Soma, Koshika; Nduaka, Chudy I.; Benda, Birgitta; Gruben, David; Nakamura, Hiroyuki; Komuro, Yoshihiro; Zwillich, Samuel H.; Wang, Lisy; Riese, Richard J. 分享 收藏
Tofacitinib in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis A Randomized Trial Kremer, Joel; Li, Zhan-Guo; Hall, Stephen; Fleischmann, Roy; Genovese, Mark; Martin-Mola, Emilio; Isaacs, John D.; Gruben, David; Wallenstein, Gene; Krishnaswami, Sriram; Zwillich, Samuel H.; Koncz, Tamas; Riese, Richard; Bradley, John 分享 收藏
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TOFACITINIB (CP-690,550), AN ORAL JANUS KINASE INHIBITOR: ANALYSIS OF GASTROINTESTINAL ADVERSE EVENTS ACROSS THE RHEUMATOID ARTHRITIS CLINICAL PROGRAMME Lee, E. B.; Curtis, J. R.; Riese, R.; Connell, C.; Chew, R.; Boy, M.; Maller, E.; Su, C.; Wang, L.; Bradley, J. 分享 收藏
CARDIOVASCULAR SAFETY FINDINGS IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH TOFACITINIB (CP-690,550), A NOVEL, ORAL JAK INHIBITOR Charles-Schoeman, C.; Wicker, P.; Sechtem, U.; Gonzalez-Gay, M. A.; Wood, S.; Boy, M.; Geier, J.; Gruben, D.; Soma, K.; Riese, R.; Bradley, J. 分享 收藏
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