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K

Kazuhiko Takehara

University of Tokyo

84H指数
545论文数
2.3W被引数
收录论文 158
发表时间
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GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region
errNATURE COMMUNICATIONS
IF15.7
err2024-01-31
err4
errOAAI
errIshikawa, Yuki; Tanaka, Nao; Asano, Yoshihide; Kodera, Masanari; Shirai, Yuichiro; Akahoshi, Mitsuteru; Hasegawa, Minoru; Matsushita, Takashi; Saito, Kazuyoshi; Motegi, Sei-ichiro; Yoshifuji, Hajime; Yoshizaki, Ayumi; Kohmoto, Tomohiro; Takagi, Kae; Oka, Akira; Kanda, Miho; Tanaka, Yoshihito; Ito, Yumi; Nakano, Kazuhisa; Kasamatsu, Hiroshi; Utsunomiya, Akira; Sekiguchi, Akiko; Niiro, Hiroaki; Jinnin, Masatoshi; Makino, Katsunari; Makino, Takamitsu; Ihn, Hironobu; Yamamoto, Motohisa; Suzuki, Chisako; Takahashi, Hiroki; Nishida, Emi; Morita, Akimichi; Yamamoto, Toshiyuki; Fujimoto, Manabu; Kondo, Yuya; Goto, Daisuke; Sumida, Takayuki; Ayuzawa, Naho; Yanagida, Hidetoshi; Horita, Tetsuya; Atsumi, Tatsuya; Endo, Hirahito; Shima, Yoshihito; Kumanogoh, Atsushi; Hirata, Jun; Otomo, Nao; Suetsugu, Hiroyuki; Koike, Yoshinao; Tomizuka, Kohei; Yoshino, Soichiro; Liu, Xiaoxi; Ito, Shuji; Hikino, Keiko; Suzuki, Akari; Momozawa, Yukihide; Ikegawa, Shiro; Tanaka, Yoshiya; Ishikawa, Osamu; Takehara, Kazuhiko; Torii, Takeshi; Sato, Shinichi; Okada, Yukinori; Mimori, Tsuneyo; Matsuda, Fumihiko; Matsuda, Koichi; Amariuta, Tiffany; Imoto, Issei; Matsuo, Keitaro; Kuwana, Masataka; Kawaguchi, Yasushi; Ohmura, Koichiro; Terao, Chikashi
err分享
err收藏
Perspective to precision medicine in scleroderma对硬皮病精准医学的展望
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-01-18
err3
errOAAI
errKomura, Kazuhiro; Yanaba, Koichi; Bouaziz, Jean-David; Yoshizaki, Ayumi; Hasegawa, Minoru; Varga, John; Takehara, Kazuhiko; Matsushita, Takashi
err分享
err收藏
A role for FcγRIIB in the development of murine bleomycin-induced fibrosis
errJOURNAL OF DERMATOLOGICAL SCIENCE
IF4
err2021-12-01
err4
errOAAI
errSawada, Kaori; Hamaguchi, Yasuhito; Mizumaki, Kie; Oishi, Kyosuke; Maeda, Shintaro; Ikawa, Yuka; Komuro, Akito; Takehara, Kazuhiko; Matsushita, Takashi
err分享
err收藏
Clinical characteristics of four myositis-specific autoantibodies with regulatory-approved testing in Japan: A Japanese multi-centre adult myositis patients' cohort
errJOURNAL OF DERMATOLOGICAL SCIENCE
IF4
err2021-07-01
err2
errOAAI
errUeda-Hayakawa, Ikuko; Fujimoto, Manabu; Sato, Shinji; Murakami, Akihiro; Kawakami, Atsushi; Mishima, Michiaki; Seishima, Mariko; Suda, Takafumi; Takehara, Kazuhiko; Mimori, Tsuneyo; Kuwana, Masataka
err分享
err收藏
CD22 and CD72 contribute to the development of scleroderma in a murine model
errJOURNAL OF DERMATOLOGICAL SCIENCE
IF4
err2020-01-01
err10
PREAI
errZhao, Chunyan; Matsushita, Takashi; Vinh Thi Ha Nguyen; Tennichi, Momoko; Fujimoto, Manabu; Takehara, Kazuhiko; Hamaguchi, Yasuhito
err分享
err收藏
Association of NCF1 polymorphism with systemic lupus erythematosus and systemic sclerosis but not with ANCA-associated vasculitis in a Japanese population
errSCIENTIFIC REPORTS
IF3.9
err2019-11-08
err19
errOAAI
errYokoyama, Nozomi; Kawasaki, Aya; Matsushita, Takashi; Furukawa, Hiroshi; Kondo, Yuya; Hirano, Fumio; Sada, Ken-ei; Matsumoto, Isao; Kusaoi, Makio; Amano, Hirofumi; Nagaoka, Shouhei; Setoguchi, Keigo; Nagai, Tatsuo; Shimada, Kota; Sugii, Shoji; Hashimoto, Atsushi; Matsui, Toshihiro; Okamoto, Akira; Chiba, Noriyuki; Suematsu, Eiichi; Ohno, Shigeru; Katayama, Masao; Migita, Kiyoshi; Kono, Hajime; Hasegawa, Minoru; Kobayashi, Shigeto; Yamada, Hidehiro; Nagasaka, Kenji; Sugihara, Takahiko; Yamagata, Kunihiro; Ozaki, Shoichi; Tamura, Naoto; Takasaki, Yoshinari; Hashimoto, Hiroshi; Makino, Hirofumi; Arimura, Yoshihiro; Harigai, Masayoshi; Sato, Shinichi; Sumida, Takayuki; Tohma, Shigeto; Takehara, Kazuhiko; Tsuchiya, Naoyuki
err分享
err收藏
Role of effector and regulatory B cells in patients with systemic sclerosis: IL-6 producing effector B cells associated with skin fibrosis
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2019-09-01
err0
errOAAI
errMatsushita, T.; Kobayashi, T.; Kano, M.; Hamaguchi, Y.; Hasegawa, M.; Fujimoto, M.; Takehara, K.
err分享
err收藏
CD22 and CD72 cooperatively contribute to the development of the reverse Arthus reaction model
errJOURNAL OF DERMATOLOGICAL SCIENCE
IF4
err2019-07-01
err3
errOAAI
errVinh Thi Ha Nguyen; Matsushita, Takashi; Zhao, Chunyan; Fujimoto, Manabu; Takehara, Kazuhiko; Tedder, Thomas F.; Hamaguchi, Yasuhito
err分享
err收藏
Regulatory B1a Cells Suppress Melanoma Tumor Immunity via IL-10 Production and Inhibiting T Helper Type 1 Cytokine Production in Tumor-Infiltrating CD8+ T Cells
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2019-07-01
err37
errOAAI
errKobayashi, Tadahiro; Oishi, Kyosuke; Okamura, Ai; Maeda, Shintaro; Komuro, Akito; Hamaguchi, Yasuhito; Fujimoto, Manabu; Takehara, Kazuhiko; Matsushita, Takashi
err分享
err收藏
Attenuation of murine sclerodermatous models by the selective S1P1 receptor modulator cenerimod
errSCIENTIFIC REPORTS
IF3.9
err2019-01-24
err18
errOAAI
errKano, Miyu; Kobayashi, Tadahiro; Date, Mutsumi; Tennichi, Momoko; Hamaguchi, Yasuhito; Strasser, Daniel S.; Takehara, Kazuhiko; Matsushita, Takashi
err分享
err收藏
Soluble CD163 is a potential biomarker in systemic sclerosis可溶性CD163是系统性硬化症的潜在生物标志物
errEXPERT REVIEW OF MOLECULAR DIAGNOSTICS
IF3.6
err2019-01-22
err12
errOAAI
errMatsushita, Takashi; Takehara, Kazuhiko
err分享
err收藏
Autoantibody to transcriptional intermediary factor-1β as a myositis-specific antibody: clinical correlation with clinically amyopathic dermatomyositis or dermatomyositis with mild myopathy
errBRITISH JOURNAL OF DERMATOLOGY
IF9.6
err2018-10-10
err8
PREAI
errUeda-Hayakawa, I.; Hamaguchi, Y.; Okiyama, N.; Motegi, S.; Yamaoka, T.; Miyake, S.; Higashi, A.; Okamoto, H.; Takehara, K.; Fujimoto, M.
err分享
err收藏
BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balanceBAFF抑制通过调节调节和效应b细胞平衡来减轻硬皮病中的纤维化
errSCIENCE ADVANCES
IF12.5
err2018-07-06
err107
errOAAI
errMatsushita, Takashi; Kobayashi, Tadahiro; Mizumaki, Kie; Kano, Miyu; Sawada, Tomoyo; Tennichi, Momoko; Okamura, Ai; Hamaguchi, Yasuhito; Iwakura, Yoichiro; Hasegawa, Minoru; Fujimoto, Manabu; Takehara, Kazuhiko
err分享
err收藏
DRB1 is the primary genetic locus contributing to susceptibility to dermatomyositis positive for anti-TIF1γ antibody in Japanese
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2018-05-01
err0
errOAAI
errYamaguchi, Y.; Kuwana, M.; Kanaoka, M.; Watanabe, T.; Okiyama, N.; Gono, T.; Kodera, M.; Kambara, T.; Hamaguchi, Y.; Seishima, M.; Takehara, K.; Fujimoto, M.; Aihara, M.
err分享
err收藏
Tumor-infiltrating CD5+ regulatory B1 cells suppress melanoma tumor immunity via inhibiting cytokine production of tumor-infiltrating CD8+ T cells
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2018-05-01
err0
errOAAI
errKobayashi, T.; Matsushita, T.; Hamaguchi, Y.; Fujimoto, M.; Takehara, K.
err分享
err收藏
IL-6-producing effector B cell promotes fibrosis in scleroderma, while IL-10-producing regulatory B cells suppresses it; BAFF inhibition modulating effector and regulatory B cell balance
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2018-05-01
err0
PREAI
errMatsushita, T.; Kobayashi, T.; Hamaguchi, Y.; Hasegawa, M.; Fujimoto, M.; Takehara, K.
err分享
err收藏
Four cases of anti-Mi-2 antibody-positive dermatomyositis: relationship between anti-Mi-2 antibody titre and disease severity and activity
errJOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
IF8
err2018-01-05
err10
PREAI
errMatsuda, T.; Ueda-Hayakawa, I.; Kambe, N.; Son, Y.; Ozaki, Y.; Hamaguchi, Y.; Takehara, K.; Fujimoto, M.; Okamoto, H.
err分享
err收藏
Inhibition of p38 MAP kinase suppresses murine Sclerodermatous Chronic Graft-Versus-Host Disease
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2017-10-01
err0
errOAAI
errMatsushita, T.; Date, M.; Hamaguchi, Y.; Hasegawa, M.; Fujimoto, M.; Takehara, K.
err分享
err收藏
RXRB Is an MHC-Encoded Susceptibility Gene Associated with Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2017-09-01
err3
errOAAI
errOka, Akira; Asano, Yoshihide; Hasegawa, Minoru; Fujimoto, Manabu; Ishikawa, Osamu; Kuwana, Masataka; Kawaguchi, Yasushi; Yamamoto, Toshiyuki; Takahashi, Hiroki; Goto, Daisuke; Endo, Hirahito; Jinnin, Masatoshi; Mano, Shuhei; Hosomichi, Kazuyoshi; Mabuchi, Tomotaka; Ueda, Mahoko Takahashi; Nakagawa, So; Beck, Stephan; Bahram, Seiamak; Takehara, Kazuhiko; Sato, Shinichi; Ihn, Hironobu
err分享
err收藏
An update on biomarker discovery and use in systemic sclerosis
errEXPERT REVIEW OF MOLECULAR DIAGNOSTICS
IF3.6
err2017-07-25
err16
PREAI
errMatsushita, Takashi; Takehara, Kazuhiko
err分享
err收藏

研究方向

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合作学者
合作期刊
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Peter ten Dijke
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H 指数: 143 · 论文数: 947
K
Kohei Miyazono
H 指数: 138 · 论文数: 709
T
Thomas F. Tedder
H 指数: 123 · 论文数: 409
R
Robert Landewé
H 指数: 118 · 论文数: 903
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