Grant R. MacGregor - Publications, H-index & Citations

Grant R. MacGregor

University of California System

40H指数

117论文数

1.6W被引数

收录论文 36

发表时间

Abi3S212F Alzheimer's disease variant alters plaque structure and disrupts microglia Abi3S212F阿尔茨海默病变异体改变斑块结构并破坏小胶质细胞

alzheimer's & dementia

IF0

2026-05-06

OAAI

Claire A. Butler; Min Sung Gee; Katie O'Gara; Giedre Milinkeviciute; Celia Da Cunha; Shimako Kawauchi; Yueh-Hao Lu; Nellie Kwang; Kate I. Tsourmas; Christiana Prekopa; Zechuan Shi; Heidi Yahan Liang; Sherilyn D. Collins; Zachary A. Pashkutz; Jenna A. Sanchez; Kai-Xuan Shi; Amber D. Walker; Shuling Wang; Maigan L. A. Wong; Karina Genaro; Jonathan Neumann; Angela Gomez-Arboledas; Duc M. Duong; Nicholas T. Seyfried; Andrea J. Tenner; Frank M. LaFerla; Ali Mortazavi; Vivek Swarup; Grant R. MacGregor; Kim N. Green

The TREM2 R47H variant is associated with liver-plasma-brain axis dyshomeostasis in the 5xFAD mouse model of Alzheimer’s disease TREM2 R47H变异与阿尔茨海默病5xFAD小鼠模型中肝-血浆-脑轴失衡相关

Neurobiology of Aging

IF3.5

2026-04-29

OAAI

Gina Faraci; Benjamin Goodfriend; Joseph Bishop; Michael Vu; Julio Avelar-Barragan; Sage Dunham; Jason Rothman; Katrine Whiteson; Amrita K Cheema; Giedre Milinkeviciute; Andrea J Tenner; Frank M LaFerla; Grant R MacGregor; Kim N Green; Mark Mapstone

Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains capture global and local expression variation 8种实验室和野生来源的小鼠品系中8种组织的系统性细胞类型解析转录组捕获全局和局部表达变异

Cell Genomics

IF9

2026-04-01

OAAI

Rebboah, Elisabeth; Weber, Ryan; Abdollahzadeh, Elnaz; Swarna, Nikhila; Sullivan, Delaney K.; Trout, Diane; Reese, Fairlie; Liang, Heidi Yahan; Filimban, Ghassan; Mahdipoor, Parvin; Duffield, Margaret; Mojaverzargar, Romina; Taghizadeh, Erisa; Fattahi, Negar; Mojgani, Negar; Zhang, Haoran; Loving, Rebekah K.; Carilli, Maria; Booeshaghi, A. Sina; Kawauchi, Shimako; Hallgrimsdottir, Ingileif B.; Williams, Brian A.; MacGregor, Grant R.; Pachter, Lior; Wold, Barbara J.; Mortazavi, Ali

Long-read sequencing transcriptome quantification with lr-kallisto 使用lr-kallisto的长读长测序转录组定量

PLOS COMPUTATIONAL BIOLOGY

IF3.6

2025-12-01

PREAI

Loving, Rebekah K.; Sullivan, Delaney K.; Reese, Fairlie; Rebboah, Elisabeth; Sakr, Jasmine; Rezaie, Narges; Liang, Heidi Y.; Filimban, Ghassan; Kawauchi, Shimako; Booeshaghi, A. Sina; Melsted, Pall; Oakes, Conrad; Trout, Diane; Williams, Brian A.; MacGregor, Grant R.; Wold, Barbara J.; Mortazavi, Ali; Pachter, Lior

Generation of an Inducible Destabilized-Domain Cre Mouse Line to Target Disease Associated Microglia

GLIA

IF5.1

2025-02-01

PREAI

Henningfield, Caden M.; Ngo, Minh; Murray, Kaitlin M.; Kwang, Nellie E.; Tsourmas, Kate I.; Neumann, Jonathan; Pashkutz, Zachary A.; Kawauchi, Shimako; Swarup, Vivek; Lane, Thomas E.; Macgregor, Grant R.; Green, Kim N.

APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology APOE Christchurch增强了与疾病相关的小胶质细胞对斑块的反应，但抑制了对tau病理的反应

MOLECULAR NEURODEGENERATION

IF17.5

2025-01-22

OAAI

Tran, Kristine M.; Kwang, Nellie E.; Butler, Claire A.; Gomez-Arboledas, Angela; Kawauchi, Shimako; Mar, Cassandra; Chao, Donna; Barahona, Rocio A.; Da Cunha, Celia; Tsourmas, Kate I.; Shi, Zechuan; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Alcantara, Joshua A.; Neumann, Jonathan; Duong, Duc M.; Seyfried, Nicholas T.; Tenner, Andrea J.; Laferla, Frank M.; Hohsfield, Lindsay A.; Swarup, Vivek; Macgregor, Grant R.; Green, Kim N.

Mitochondrial DNA lineages determine tumor progression through T cell reactive oxygen signaling 线粒体DNA谱系通过T细胞反应性氧信号调控肿瘤进展

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-01-03

OAAI

Yardeni, Tal; Olali, Arnold Z.; Chen, Hsiao-Wen; Wang, Liqing; Halton, Jeffrey A.; Zenab, Angi; Morrow, Ryan; Butic, Arrienne; Murdock, Deborah G.; Waymire, Katrina G.; Macgregor, Grant R.; Boursi, Ben; Beier, Ulf H.; Hancock, Wayne W.; Wallace, Douglas C.

Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk gene mutation

MOLECULAR PSYCHIATRY

IF10.1

2024-08-05

OAAI

Johnston, Kevin G.; Berackey, Bereket T.; Tran, Kristine M.; Gelber, Alon; Yu, Zhaoxia; Macregor, Grant R.; Mukamel, Eran A.; Tan, Zhiqun; Green, Kim N.; Xu, Xiangmin

Cystatin F attenuates neuroinflammation and demyelination following murine coronavirus infection of the central nervous system

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-06-15

OAAI

Syage, Amber R.; Pachow, Collin; Murray, Kaitlin M.; Henningfield, Caden; Fernandez, Kellie; Du, Annie; Cheng, Yuting; Olivarria, Gema; Kawauchi, Shimako; Macgregor, Grant R.; Green, Kim N.; Lane, Thomas E.

Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice AD基因型与人类 β 淀粉样蛋白敲入 (haβ-ki) 小鼠的微生物组之间的性别特异性关联

ALZHEIMERS & DEMENTIA

IF11.1

2024-04-04

OAAI

Dunham, Sage J. B.; Avelar-Barragan, Julio; Rothman, Jason A.; Adams, Eric D.; Faraci, Gina; Forner, Stefania; Kawauchi, Shimako; Tenner, Andrea J.; Green, Kim N.; LaFerla, Frank M.; MacGregor, Grant R.; Mapstone, Mark; Whiteson, Katrine L.

The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage

ALZHEIMERS & DEMENTIA

IF11.1

2024-03-20

OAAI

Butler, Claire A.; Arvilla, Adrian Mendoza; Milinkeviciute, Giedre; Da Cunha, Celia; Kawauchi, Shimako; Rezaie, Narges; Liang, Heidi Y.; Javonillo, Dominic; Thach, Annie; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Gomez-Arboledas, Angela; Henningfield, Caden M.; Hohsfield, Lindsay A.; Mapstone, Mark; Tenner, Andrea J.; LaFerla, Frank M.; Mortazavi, Ali; MacGregor, Grant R.; Green, Kim N.

BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2024-03-09

OAAI

Garcia-Agudo, Laura Fernandez; Shi, Zechuan; Smith, Ian F.; Kramar, Eniko A.; Tran, Katelynn; Kawauchi, Shimako; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Liang, Heidi Yahan; Da Cunha, Celia; Milinkeviciute, Giedre; Morabito, Samuel; Miyoshi, Emily; Rezaie, Narges; Gomez-Arboledas, Angela; Arvilla, Adrian Mendoza; Ghaemi, Daryan Iman; Tenner, Andrea J.; LaFerla, Frank M.; Wood, Marcelo A.; Mortazavi, Ali; Swarup, Vivek; MacGregor, Grant R.; Green, Kim N.

Genetic diversity promotes resilience in a mouse model of Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2024-03-01

OAAI

Soni, Neelakshi; Hohsfield, Lindsay A.; Tran, Kristine M.; Kawauchi, Shimako; Walker, Amber; Javonillo, Dominic; Phan, Jimmy; Matheos, Dina; Da Cunha, Celia; Uyar, Asli; Milinkeviciute, Giedre; Gomez-Arboledas, Angela; Tran, Katelynn; Kaczorowski, Catherine C.; Wood, Marcelo A.; Tenner, Andrea J.; LaFerla, Frank M.; Carter, Gregory .; Mortazavi, Ali; Swarup, Vivek; MacGregor, Grant R.; Green, Kim N.

Dual roles of myocardial mitochondrial AKT on diabetic cardiomyopathy and whole body metabolism

CARDIOVASCULAR DIABETOLOGY

IF10.6

2023-10-27

OAAI

Chen, Yu-Han; Ta, Albert P.; Chen, Yumay; Lee, Hsiao-Chen; Fan, Wenjun; Chen, Phang-Lang; Jordan, Maria C.; Roos, Kenneth P.; MacGregor, Grant R.; Yang, Qin; Edwards, Robert A.; Li, Junfeng; Wang, Ping H.

A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques 没有隐性剪接的Trem2R47H小鼠模型驱动年龄和疾病依赖性组织损伤和响应于斑块的突触丢失

MOLECULAR NEURODEGENERATION

IF17.5

2023-02-17

OAAI

Tran, Kristine M. M.; Kawauchi, Shimako; Kramar, Eniko A.; Rezaie, Narges; Liang, Heidi Yahan; Sakr, Jasmine S. S.; Gomez-Arboledas, Angela; Arreola, Miguel A. A.; da Cunha, Celia; Phan, Jimmy; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Filimban, Ghassan; Shi, Zechuan; Milinkeviciute, Giedre; Javonillo, Dominic I. I.; Tran, Katelynn; Gantuz, Magdalena; Forner, Stefania; Swarup, Vivek; Tenner, Andrea J. J.; LaFerla, Frank M. M.; Wood, Marcelo A. A.; Mortazavi, Ali; MacGregor, Grant R. R.; Green, Kim N. N.

Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease 阿尔茨海默病3xTg-AD小鼠模型的系统表型和表征

FRONTIERS IN NEUROSCIENCE

IF3.2

2022-01-24

OAAI

Javonillo, Dominic I.; Tran, Kristine M.; Phan, Jimmy; Hingco, Edna; Kramar, Enikoe A.; da Cunha, Celia; Forner, Stefania; Kawauchi, Shimako; Milinkeviciute, Giedre; Gomez-Arboledas, Angela; Neumann, Jonathan; Banh, Crystal E.; Huynh, Michelle; Matheos, Dina P.; Rezaie, Narges; Alcantara, Joshua A.; Mortazavi, Ali; Wood, Marcelo A.; Tenner, Andrea J.; MacGregor, Grant R.; Green, Kim N.; LaFerla, Frank M.

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology

NATURE COMMUNICATIONS

IF15.7

2021-04-23

OAAI

Baglietto-Vargas, David; Forner, Stefania; Cai, Lena; Martini, Alessandra C.; Trujillo-Estrada, Laura; Swarup, Vivek; Marie Minh Thu Nguyen; Kelly Do Huynh; Javonillo, Dominic, I; Kristine Minh Tran; Phan, Jimmy; Jiang, Shan; Kramar, Eniko A.; Nunez-Diaz, Cristina; Balderrama-Gutierrez, Gabriela; Garcia, Franklin; Childs, Jessica; Rodriguez-Ortiz, Carlos J.; Antonio Garcia-Leon, Juan; Kitazawa, Masashi; Shahnawaz, Mohammad; Matheos, Dina P.; Ma, Xinyi; Da Cunha, Celia; Walls, Ken C.; Ager, Rahasson R.; Soto, Claudio; Gutierrez, Antonia; Moreno-Gonzalez, Ines; Mortazavi, Ali; Tenner, Andrea J.; MacGregor, Grant R.; Wood, Marcelo; Green, Kim N.; LaFerla, Frank M.

Tubular mitochondrial AKT1 is activated during ischemia reperfusion injury and has a critical role in predisposition to chronic kidney disease

KIDNEY INTERNATIONAL

IF12.6

2021-04-01

OAAI

Lin, Hugo Y-H; Chen, Yumay; Chen, Yu-Han; Ta, Albert P.; Lee, Hsiao-Chen; MacGregor, Grant R.; Vaziri, Nosratola D.; Wang, Ping H.

Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD

ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS

IF6.8

2020-11-23

OAAI

Oblak, Adrian L.; Forner, Stefania; Territo, Paul R.; Sasner, Michael; Carter, Gregory W.; Howell, Gareth R.; Sukoff-Rizzo, Stacey J.; Logsdon, Benjamin A.; Mangravite, Lara M.; Mortazavi, Ali; Baglietto-Vargas, David; Green, Kim N.; MacGregor, Grant R.; Wood, Marcelo A.; Tenner, Andrea J.; LaFerla, Frank M.; Lamb, Bruce T.

Delineating the role of MITF isoforms in pigmentation and tissue homeostasis 描述MITF同工型在色素沉着和组织稳态中的作用

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2019-10-16

OAAI

Flesher, Jessica L.; Paterson-Coleman, Elyse K.; Vasudeva, Priya; Ruiz-Vega, Rolando; Marshall, Michaela; Pearlman, Eric; MacGregor, Grant R.; Neumann, Jonathan; Ganesan, Anand K.

研究方向