J. Sjef Verbeek

Leiden University

59H指数

175论文数

1.1W被引数

收录论文 77

发表时间

Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors

CELL REPORTS

IF6.9

2022-02-01

OAAI

Sahin, Mehmet; Remy, Melissa M.; Fallet, Benedict; Sommerstein, Rami; Florova, Marianna; Langner, Anna; Klausz, Katja; Straub, Tobias; Kreutzfeldt, Mario; Wagner, Ingrid; Schmidt, Cinzia T.; Malinge, Pauline; Magistrelli, Giovanni; Izui, Shozo; Pircher, Hanspeter; Verbeek, J. Sjef; Merkler, Doron; Peipp, Matthias; Pinschewer, Daniel D.

Isotype selection for antibody-based cancer therapy

CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IF3.8

2020-11-30

OAAI

Vukovic, N.; van Elsas, A.; Verbeek, J. S.; Zaiss, D. M. W.

Immunogenicity of rat-neu+ mouse mammary tumours determines the T cell-dependent therapeutic efficacy of anti-neu monoclonal antibody treatment

SCIENTIFIC REPORTS

IF3.9

2020-03-03

OAAI

Sow, Heng Sheng; Benonisson, Hreinn; Brouwers, Conny; Linssen, Margot M.; Camps, Marcel; Breukel, Cor; Claassens, Jill; van Hall, Thorbald; Ossendorp, Ferry; Fransen, Marieke F.; Verbeek, J. Sjef

The Complex Association of FcγRIIb With Autoimmune Susceptibility

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-10-15

OAAI

Verbeek, J. Sjef; Hirose, Sachiko; Nishimura, Hiroyuki

Fc Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus

VIRUSES-BASEL

IF3.5

2019-02-08

OAAI

Banki, Zoltan; Werner, Roland; Riepler, Lydia; Roessler, Annika; Muellauer, Brigitte; Hegen, Verena; Bayer, Wibke; Verbeek, J. Sjef; Dittmer, Ulf; Stoiber, Heribert

CD3-Bispecific Antibody Therapy Turns Solid Tumors into Inflammatory Sites but Does Not Install Protective Memory

MOLECULAR CANCER THERAPEUTICS

IF5.5

2019-02-04

OAAI

Benonisson, Hreinn; Altintas, Isil; Sluijter, Marjolein; Verploegen, Sandra; Labrijn, Aran F.; Schuurhuis, Danita H.; Houtkamp, Mischa A.; Verbeek, J. Sjef; Schuurman, Janine; van Hall, Thorbald

A Dual-Color Bioluminescence Reporter Mouse for Simultaneous in vivo Imaging of T Cell Localization and Function 双色生物发光报告小鼠，用于T细胞定位和功能的同时体内成像

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-01-08

OAAI

Kleinovink, Jan Willem; Mezzanotte, Laura; Zambito, Giorgia; Fransen, Marieke F.; Cruz, Luis J.; Verbeek, J. Sjef; Chan, Alan; Ossendorp, Ferry; Lowik, Clemens

High FcγR Expression on Intratumoral Macrophages Enhances Tumor-Targeting Antibody Therapy

JOURNAL OF IMMUNOLOGY

IF3.4

2018-12-15

OAAI

Benonisson, Hreinn; Sow, Heng Sheng; Breukel, Cor; Claassens, Jill; Brouwers, Conny; Linssen, Margot M.; Fransen, Marieke F.; Sluijter, Marjolein; Ossendorp, Ferry; van Hall, Thorbald; Verbeek, J. Sjef

FcγRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus- Prone Yaa Mice

JOURNAL OF IMMUNOLOGY

IF3.4

2018-12-01

OAAI

Lin, Qingshun; Ohtsuji, Mareki; Amano, Hirofumi; Tsurui, Hiromichi; Tada, Norihiro; Sato, Ryota; Fukuyama, Hidehiro; Nishimura, Hiroyuki; Verbeek, J. Sjef; Hirose, Sachiko

FcγR interaction is not required for effective anti-PD-L1 immunotherapy but can add additional benefit depending on the tumor model

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2018-11-12

OAAI

Sow, Heng Sheng; Benonisson, Hreinn; Breukel, Cor; Visser, Remco; Verhagen, Onno J. H. M.; Bentlage, Arthur E. H.; Brouwers, Conny; Claassens, Jill W. C.; Linssen, Margot M.; Camps, Marcel; van Hall, Thorbald; Ossendorp, Ferry; Fransen, Marieke F.; Vidarsson, Gestur; Verbeek, J. Sjef

Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function 共刺激受体4-1BB抗体通过T调节细胞耗竭和促进CD8 T细胞效应功能增强抗肿瘤免疫

IMMUNITY

IF26.3

2018-11-01

119

OAAI

Buchan, Sarah L.; Dou, Lang; Remer, Marcus; Booth, Steven G.; Dunn, Stuart N.; Lai, Chester; Semmrich, Monika; Teige, Ingrid; Martensson, Linda; Penfold, Christine A.; Chan, H. T. Claude; Willoughby, Jane E.; Mockridge, C. Ian; Dahal, Lekh N.; Cleary, Kirstie L. S.; James, Sonya; Rogel, Anne; Kannisto, Paivi; Jernetz, Mats; Williams, Emily L.; Healy, Eugene; Verbeek, J. Sjef; Johnson, Peter W. M.; Frendeus, Bjorn; Cragg, Mark S.; Glennie, Martin J.; Gray, Juliet C.; Al-Shamkhani, Aymen; Beers, Stephen A.

A Restricted Role for FcγR in the Regulation of Adaptive Immunity

JOURNAL OF IMMUNOLOGY

IF3.4

2018-04-15

OAAI

Fransen, Marieke F.; Benonisson, Hreinn; van Maren, Wendy W.; Sow, Heng Sheng; Breuke, Cor; Linssen, Margot M.; Claassens, Jill W. C.; Brouwers, Conny; van der Kaa, Jos; Camps, Marcel; Kleinovink, Jan Willem; Vonk, Kelly K.; van Heiningen, Sandra; Klar, Ngaisah; van Beek, Lianne; van Harmelen, Vanessa; Daxinger, Lucia; Nandakumar, Kutty S.; Holmdahl, Rikard; Coward, Chris; Lin, Qingshun; Hirose, Sachiko; Salvatori, Daniela; van Hall, Thorbald; van Kooten, Cees; Mastroeni, Piero; Ossendorp, Ferry; Verbeekt, J. Sjef

Anti-Tumor Necrosis Factor With a Glyco-Engineered Fc-Region Has Increased Efficacy in Mice With Colitis

GASTROENTEROLOGY

IF25.1

2017-11-01

PREAI

Bloemendaal, Felicia M.; Levin, Alon D.; Wildenberg, Manon E.; Koelink, Pim J.; McRae, Bradford L.; Salfeld, Jochen; Lum, Jenifer; Kolfschoten, Marijn van der Neut; Claassens, Jill W.; Visser, Remco; Bentlage, Arthur; D'Haens, Geert R. A. M.; Verbeek, J. Sjef; Vidarsson, Gestur; van den Brink, Gijs R.

C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes 体内形成的抗原-抗体复合物的C1q-Dependent树突状细胞交叉呈递

JOURNAL OF IMMUNOLOGY

IF3.4

2017-06-01

OAAI

Ho, Nataschja I.; Camps, Marcel G. M.; de Haas, Edwin F. E.; Trouw, Leendert A.; Verbeek, J. Sjef; Ossendorp, Ferry

Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2017-02-01

PREAI

Hartholt, R. B.; Wroblewska, A.; Herczenik, E.; Peyron, I.; Ten Brinke, A.; Rispens, T.; Nolte, M. A.; Slot, E.; Claassens, J. W.; Nimmerjahn, F.; Verbeek, J. S.; Voorberg, J.

The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2015-12-29

OAAI

Rutten, Julie W.; Klever, Roselin R.; Hegeman, Ingrid M.; Poole, Dana S.; Dauwerse, Hans G.; Broos, Ludo A. M.; Breukel, Cor; Aartsma-Rus, Annemieke M.; Verbeek, J. Sjef; van der Weerd, Louise; van Duinen, Sjoerd G.; van den Maagdenberg, Arn M. J. M.; Oberstein, Saskia A. J. Lesnik

FcRγ-Chain Deficiency Reduces the Development of Diet-Induced Obesity

OBESITY

IF4.7

2015-11-02

OAAI

van Beek, Lianne; Vroegrijk, Irene O. C. M.; Katiraei, Saeed; Heemskerk, Mattijs M.; van Dam, Andrea D.; Kooijman, Sander; Rensen, Patrick C. N.; Koning, Frits; Verbeek, J. Sjef; van Dijk, Ko Willems; van Harmelen, Vanessa

Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair

PLOS PATHOGENS

IF4.9

2015-03-25

OAAI

Esser-von Bieren, Julia; Volpe, Beatrice; Sutherland, Duncan B.; Buergi, Jerome; Verbeek, J. Sjef; Marsland, Benjamin J.; Urban, Joseph F., Jr.; Harris, Nicola L.

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fcγ Receptor I

JOURNAL OF IMMUNOLOGY

IF3.4

2015-02-01

OAAI

Bieren, Julia Esser-von; Volpe, Beatrice; Kulagin, Manuel; Sutherland, Duncan B.; Guiet, Romain; Seitz, Arne; Marsland, Benjamin J.; Verbeek, J. Sjef; Harris, Nicola L.

FcRγ-Chain ITAM Signaling Is Critically Required for Cross-Presentation of Soluble Antibody-Antigen Complexes by Dendritic Cells Fcr γ 链ITAM信号是树突状细胞交叉呈递可溶性抗体-抗原复合物的关键

JOURNAL OF IMMUNOLOGY

IF3.4

2014-12-01

OAAI

Boross, Peter; van Montfoort, Nadine; Stapels, Daphne A. C.; van der Poel, Cees E.; Bertens, Christian; Meeldijk, Jan; Jansen, J. H. Marco; Verbeek, J. Sjef; Ossendorp, Ferry; Wubbolts, Richard; Leusen, Jeanette H. W.

研究方向