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收藏Article A bacterial genotoxin reveals a p53-proteasomeLC3 regulatory axis that drives the suppression of autophagy in cells experiencing sublethal DNA damage文章 A:一种细菌基因毒素揭示了一个p53-蛋白酶体LC3调控轴,该轴驱动在经历亚致死性DNA损伤的细胞中自噬的抑制。
Lieu, D'Feau J.; Crowder, Molly K.; Kryza, Jordan R.; Tamilselvam, Batcha; Kaminski, Paul J.; Kim, Ik-Jung; Li, Ying-Xing; Jeong, Eunji; Enkhbaatar, Michidmaa; Chen, Henry; Son, Sophia B.; Mok, Hanlin; Bradley, Kenneth A.; Phillips, Heidi; Blanke, Steven R.
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收藏Development of a gene expression-based prognostic signature for IDH wild-type glioblastoma
Johnson, Radia M.; Phillips, Heidi S.; Bais, Carlos; Brennan, Cameron W.; Cloughesy, Timothy F.; Daemen, Anneleen; Herrlinger, Ulrich; Jenkins, Robert B.; Lai, Albert; Mancao, Christoph; Weller, Michael; Wick, Wolfgang; Bourgon, Richard; Garcia, Josep
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收藏Synergistic combination of oncolytic virotherapy and immunotherapy for glioma
Tang, Bingtao; Guo, Zong Sheng; Bartlett, David; Liu, Jia; McFadden, Grant; Shisler, Joanna; Foss, Kari; Phillips, Heidi; Lichtor, Terence; Roy, Edward
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收藏Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis
Phillips, Gail D. Lewis; Nishimura, Merry C.; Lacap, Jennifer Arca; Kharbanda, Samir; Mai, Elaine; Tien, Janet; Malesky, Kimberly; Williams, Simon P.; Marik, Jan; Phillips, Heidi S.
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收藏CORRELATION OF MOLECULAR SUBTYPES WITH OVERALL SURVIVAL (OS) IN AVAGLIO, A RANDOMIZED, PLACEBO-CONTROLLED STUDY OF BEVACIZUMAB (BEV) PLUS RADIOTHERAPY (RT) AND TEMOZOLOMIDE (TMZ) FOR NEWLY DIAGNOSED GLIOBLASTOMA (GBM)
Phillips, Heidi; Sandmann, Thomas; Li, Congfen; Cloughesy, Timothy; Chinot, Olivier L.; Wick, Wolfgang; Nishikawa, Ryo; Mason, Warren; Henriksson, Roger; Saran, Frank; Lai, Albert; Moore, Nicola; Hegde, Priti; Abrey, Lauren; Bourgon, Richard; Garcia, Josep; Bais, Carlos
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收藏Preclinical efficacy of GNE-317, a dual PI3K/mTOR inhibitor, with or without bevacizumab in EGFR and/or PTEN-mutated glioblastoma multiforme
Sio, Terence T.; Pokorny, Jenny L.; Mladek, Ann C.; Carlson, Brett L.; Schroeder, Mark A.; Iyekegbe, Dennis O.; Bakken, Katrina; Salphati, Laurent; Phillips, Heidi; Sarkaria, Jann N.
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收藏Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma
Chen, Ruihuan; Nishimura, Merry C.; Kharbanda, Samir; Peale, Frank; Deng, Yuzhong; Daemen, Anneleen; Forrest, William F.; Kwong, Mandy; Hedehus, Maj; Hatzivassiliou, Georgia; Friedman, Lori S.; Phillips, Heidi S.
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收藏Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells缺氧和氧合诱导胶质瘤干细胞样细胞中磷酸戊糖途径与糖酵解之间的代谢转换
Kathagen, Annegret; Schulte, Alexander; Balcke, Gerd; Phillips, Heidi S.; Martens, Tobias; Matschke, Jakob; Guenther, Hauke S.; Soriano, Robert; Modrusan, Zora; Sandmann, Thomas; Kuhl, Carsten; Tissier, Alain; Holz, Mareike; Krawinkel, Lutz A.; Glatzel, Markus; Westphal, Manfred; Lamszus, Katrin
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收藏Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent
Merchant, Mark; Ma, Xiaolei; Maun, Henry R.; Zheng, Zhong; Peng, Jing; Romero, Mally; Huang, Arthur; Yang, Nai-ying; Nishimura, Merry; Greve, Joan; Santell, Lydia; Zhang, Yu-Wen; Su, Yanli; Kaufman, Dafna W.; Billeci, Karen L.; Mai, Elaine; Moffat, Barbara; Lim, Amy; Duenas, Eileen T.; Phillips, Heidi S.; Xiang, Hong; Young, Judy C.; Vande Woude, George F.; Dennis, Mark S.; Reilly, Dorothea E.; Schwall, Ralph H.; Starovasnik, Melissa A.; Lazarus, Robert A.; Yansura, Daniel G.
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收藏PDGFRA Amplification is Common in Pediatric and Adult High-Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma
Phillips, Joanna J.; Aranda, Derick; Ellison, David W.; Judkins, Alexander R.; Croul, Sidney E.; Brat, Daniel J.; Ligon, Keith L.; Horbinski, Craig; Venneti, Sriram; Zadeh, Gelareh; Santi, Mariarita; Zhou, Shengmei; Appin, Christina L.; Sioletic, Stefano; Sullivan, Lisa M.; Martinez-Lage, Maria; Robinson, Aaron E.; Yong, William H.; Cloughesy, Timothy; Lai, Albert; Phillips, Heidi S.; Marshall, Roxanne; Mueller, Sabine; Haas-Kogan, Daphne A.; Molinaro, Annette M.; Perry, Arie
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收藏Identifying the mesenchymal molecular subtype of glioblastoma using quantitative volumetric analysis of anatomic magnetic resonance images
Naeini, Kourosh M.; Pope, Whitney B.; Cloughesy, Timothy F.; Harris, Robert J.; Lai, Albert; Eskin, Ascia; Chowdhury, Reshmi; Phillips, Heidi S.; Nghiemphu, Phioanh L.; Behbahanian, Yalda; Ellingson, Benjamin M.
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