白冠华 (Guanhua Bai)

southern university of science and technology研究助理教授

H指数:5

被引数:150

个人简介

"研究领域 1. 抑制性突触后致密带中蛋白质复合体的动态组装与相分离调控的分子机制研究； 2. 小G蛋白及其调节因子在突触形成及可塑性调控中的作用机制研究。学术成果查看更多 1. Guanhua Bai#, Ruifeng Huang#, Yinmiao Lian, Xintong Zhao, Wanfa Yang, Xiaomi Lu, Hao Li, and Mingjie Zhang*. (2026). The ARHGAP32 isoform PX-RICS is specifically targeted to inhibitory synapses by binding to gephyrin. PNAS 10.1073/pnas.2601488123. 2. Guanhua Bai#, Ruifeng Huang#, Xinyue Nan#, Mengru Zhuang, Meiling Wu, Yinmiao Lian, Qixu Cai, Honglei Tian, Youming Lu, Hao Li*, and Mingjie Zhang*. (2025). IQSEC2/BRAG1 May Modulate Postsynaptic Density Assembly Through Ca2+-Induced Phase Separation. J. Cell Biol. 224. 10.1083/jcb.202503076. 3. Guanhua Bai#, Hao Li#, Pengwei Qin, Yiqing Guo, Wanfa Yang, Yinmiao Lian, Fei Ye, JianxinChen, Meiling Wu, Ruifeng Huang, Jinsong Li, Youming Lu, Mingjie Zhang*. (2023). Ca2+-induced release of IQSEC2/BRAG1 autoinhibition under physiological and pathological conditions. J. Cell Biol. 222. 10.1083/jcb.202307117. 4. Guanhua Bai, Yu Wang, and Mingjie Zhang*. (2021). Gephyrin-mediated formation of inhibitory postsynaptic density sheet via phase separation. Cell Research 31, 312-325. 10.1038/s41422-020-00433-1. 5. Guanhua Bai and Mingjie Zhang*. (2022). Inhibitory postsynaptic density from the lens of phase separation. Oxford Open Neuroscience 1. 10.1093/oons/kvac003. 6. Guanhua Bai and Mingjie Zhang*. (2021). Mesophasic Assembly of Inhibitory Postsynaptic Density. Neuroscience bulletin 37, 141-143. 10.1007/s12264-020-00623-2. 7. Guanhua Bai and Mingjie Zhang*. (2021). Clustering acetylcholine receptors in neuromuscular junction by phase-separated Rapsn condensates. Neuron 109, 1907-1909. 10.1016/j.neuron.2021.05.024. 8. Menglong Zeng, Guanhua Bai, and Mingjie Zhang*. (2017). Anchoring high concentrations of SynGAP at postsynaptic densities via liquid-liquid phase separation. Small GTPases 10, 1-9. 10.1080/21541248.2017.1320350. 9. Bowen Jia#, Zeyu Shen#, Shihan Zhu, Jingguo Huang, Zhitao Liao, Shuaizhu Zhao, Hao Li, Shiwen Chen, Yang Xu, Yu Wang, Haitang Peng, Guanhua Bai, Youming Lu, Penger Tong, Wucheng Tao, and Mingjie Zhang*. (2025). Shank3 oligomerization governs material properties of the postsynaptic density condensate and synaptic plasticity. Cell 10.1016/j.cell.2025.07.047.\n团队成员查看更多\n加入团队查看更多\n//教师简介 $(\".js_about\").on(\"click\",function(){ var js_about = $('#js_1').offset().top; console.log(js_about); $(\"html,body\").animate({scrollTop:js_about},500) }); var vals = true; $('.links').click(function(){ console.log(vals); if( vals == true) { vals = false; $(\".js_background\").slideDown(1000); $(this).css('background-color','#666'); $(this).text('收起'); }else { vals = true; $(\".js_background\").slideUp(1000); $(this).css('background-color','#28b7bc'); $(this).text('个人简介'); } }); $(function () { $('.area_pics').on('click', '.cover', function () { var this_ = $(this); var images = this_.parents('.area_pics').find('.cover a'); var imagesArr = new Array(); $.each(images, function (i, image) { imagesArr.push($(image).children('img').attr('src')); }); $.pictureViewer({ images: imagesArr, //需要查看的图片，数据类型为数组 initImageIndex: this_.index() + 1, //初始查看第几张图片，默认1 scrollSwitch: true //是否使用鼠标滚轮切换图片，默认false }); }); });\n$(function() { $(\".successlunbo\").css(\"display\",\"block\"); $('.succesny').olvSlides({ thumb: true, thumbPage: true, thumbDirection: \"Y\", effect: 'fade' }); })\n联系我们联系地址深圳市南山区西丽学苑大道1088号南方科技大学第二科研楼401室办公电话电子邮箱 baigh@sustech.edu.cn"