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Lee J. Helman

national institutes of health (nih) - usa

83H指数
523论文数
2.3W被引数
收录论文 104
发表时间
Loss of LRRC15 in osteosarcoma cells disrupts extracellular matrix integration, intercellular communication, and differentiation
err2023-04-04
err0
PREAI
errMukherjee, Sanjit; Jajoo, Ankit; Zhu, Jack; Pineda, Marbin; Walker, Robert; Purcell, James; Helman, Lee J.; Meltzer, Paul S.
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SARC025 arms 1 and 2: A phase 1 study of the poly(ADP-ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma
errCANCER
IF5.1
err2020-12-08
err26
errOAAI
errChugh, Rashmi; Ballman, Karla, V; Helman, Lee J.; Patel, Shreyaskumar; Whelan, Jeremy S.; Widemann, Brigitte; Lu, Yao; Hawkins, Douglas S.; Mascarenhas, Leo; Glod, John W.; Ji, Jiuping; Zhang, Yiping; Reinke, Denise; Strauss, Sandra J.
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Targeting serine metabolism impairs tumor growth in preclinical models of Ewing sarcoma
err2020-08-15
err0
PREAI
errIssaq, Sameer; Mendoza, Arnulfo; Rosales, Tracy; Heske, Christine; Thomas, Craig; DeBerardinis, Ralph; Helman, Lee
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Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma
err2020-07-15
err22
errOAAI
errSlemmons, Katherine K.; Yeung, Choh; Baumgart, Joshua T.; Martinez Juarez, Jhazeel O.; McCalla, Amy; Helman, Lee J.
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EWS-FLI1-regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth
err2020-07-02
err25
errOAAI
errIssaq, Sameer H.; Mendoza, Arnulfo; Kidner, Ria; Rosales, Tracy, I; Duveau, Damien Y.; Heske, Christine M.; Rohde, Jason M.; Boxer, Matthew B.; Thomas, Craig J.; DeBerardinis, Ralph J.; Helman, Lee J.
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Molecular mechanisms of Guadecita bine induced FGFR4 down regulation in alveolar rhabdomyosarcomas
err2020-07-01
err7
errOAAI
errDarvishi, Emad; Slemmons, Katherine; Wan, Zesheng; Mitra, Sheetal; Hou, Xiaogang; Parmentier, Jean Hugues; Loh, Yong-Hwee Eddie; Helman, Lee J.
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CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma
err2020-05-04
err18
errOAAI
errFlores, Guillermo; Everett, Joel H.; Boguslawski, Elissa A.; Oswald, Brandon M.; Madaj, Zachary B.; Beddows, Ian; Dikalov, Sergey; Adams, Marie; Klumpp-Thomas, Carleen A.; Kitchen-Goosen, Susan M.; Martin, Scott E.; Caplen, Natasha J.; Helman, Lee J.; Grohar, Patrick J.
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Discovery of highly potent and selective covalent inhibitors of FGFR4
err2019-12-01
err0
PREAI
errChen, Hang; Slemmons, Katherine; Ha, Heather; Stanley, Robert; Cai, Qian; Yuan, Irene; Helman, Lee; Cao, Ping
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Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma
err2019-10-01
err99
errOAAI
errYeung, Choh; Gibson, Anna E.; Issaq, Sameer H.; Oshima, Nobu; Baumgart, Joshua T.; Edessa, Leah D.; Rai, Ganesha; Urban, Daniel J.; Johnson, Michelle S.; Benavides, Gloria A.; Squadrito, Giuseppe L.; Yohe, Marielle E.; Lei, Haiyan; Eldridge, Sandy; Hamre, John, III; Dowdy, Tyrone; Ruiz-Rodado, Victor; Lita, Adrian; Mendoza, Arnulfo; Shern, Jack F.; Larion, Mioara; Helman, Lee J.; Stott, Gordon M.; Krishna, Murali C.; Hall, Matthew D.; Darley-Usmar, Victor; Neckers, Leonard M.; Heske, Christine M.
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Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth
err2019-02-26
err47
errOAAI
errIssaq, Sameer H.; Mendoza, Arnulfo; Fox, Stephen D.; Helman, Lee J.
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DNA methyltransferase inhibitors target a YES1-YAP1 signaling axis in childhood rhabdomyosarcoma
err2018-07-01
err0
PREAI
errSlemmons, Katherine; Yeung, Choh; Baumgart, Josh; McCalla-Martin, Amy; Helman, Lee
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Suppression of EWS-FLI1 transcription using a combination therapy of mithramycin and cyclin-dependent kinase 9 inhibition
err2018-07-01
err0
PREAI
errFlores, Guillermo; Everett, Joel; Oswald, Brandon; Caplen, Natasha; Helman, Lee; Madaj, Zachary; Grohar, Patrick
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Positively selected enhancer elements endow osteosarcoma cells with metastatic competence (vol 24, pg 176, 2018)
err2018-04-01
err3
errOAAI
errMorrow, James J.; Bayles, Ian; Funnell, Alister P. W.; Miller, Tyler E.; Saiakhova, Alina; Lizardo, Michael M.; Bartels, Cynthia F.; Kapteijn, Maaike Y.; Hung, Stevephen; Mendoza, Arnulfo; Dhillon, Gursimran; Chee, Daniel R.; Myers, Jay T.; Allen, Frederick; Gambarotti, Marco; Righi, Alberto; DiFeo, Analisa; Rubin, Brian P.; Huang, Alex Y.; Meltzer, Paul S.; Helman, Lee J.; Picci, Piero; Versteeg, Henri H.; Stamatoyannopoulos, John A.; Khanna, Chand; Scacheri, Peter C.
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Positively selected enhancer elements endow osteosarcoma cells with metastatic competence
err2018-01-15
err127
errOAAI
errMorrow, James J.; Bayles, Ian; Funnell, Alister P. W.; Miller, Tyler E.; Saiakhova, Alina; Lizardo, Michael M.; Bartels, Cynthia F.; Kapteijn, Maaike Y.; Hung, Stevephen; Mendoza, Arnulfo; Dhillon, Gursimran; Chee, Daniel R.; Myers, Jay T.; Allen, Frederick; Gambarotti, Marco; Righi, Alberto; Difeo, Analisa; Rubin, Brian P.; Huang, Alex Y.; Meltzer, Paul S.; Helman, Lee J.; Picci, Piero; Versteeg, Henri H.; Stamatoyannopoulos, John A.; Khanna, Chand; Scacheri, Peter C.
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Evaluating the effect of PARP inhibitors in combination with nicotinamide phosphoribosyltransferase inhibitors in Ewing sarcoma
err2017-07-01
err0
PREAI
errBaumgart, Joshua T.; Heske, Christine; Davis, Mindy I.; Wilson, Kelli; Zhang, Xiaoha; Guha, Rajarshi; Ferrer, Marc; Mendoza, Arnulfo; Thomas, Craig J.; Helman, Lee J.
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Characterizing the role of serine metabolism in pediatric sarcomas
err2017-07-01
err0
PREAI
errIssaq, Sameer; Kidner, Ria; Rohde, Jason; Boxer, Matthew; Helman, Lee
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A simple and rapid UHPLC-MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma
err2017-01-01
err0
errOAAI
errFerraz Nogueira Filho, Marco A.; Peer, Cody J.; Nguyen, Jeffers; McCalla, Amy; Helman, Lee; Figg, William D.
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Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression
err2016-11-01
err49
errOAAI
errLizardo, Michael M.; Morrow, James J.; Miller, Tyler E.; Hong, Ellen S.; Ren, Ling; Mendoza, Arnulfo; Halsey, Charles H.; Scacheri, Peter C.; Helman, Lee J.; Khanna, Chand
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