Alois Haromy - Publications, H-index & Citations

Alois Haromy

university of alberta

28H指数

69论文数

8.4K被引数

收录论文 30

发表时间

Myofibroblast transition and loss of UCP2 in a rat model and a human pulmonary hypertension cohort underline right ventricular decompensation: potential value of a loss -of-function UCP2 SNP 肌成纤维细胞转分化及大鼠模型和人类肺动脉高压队列中UCP2的缺失凸显了右心室失代偿：UCP2功能缺失型SNP的潜在价值

CIRCULATION

IF38.6

2024-11-12

PREAI

Zhang, Yongneng; Haromy, Alois; Liu, Yongsheng; Zhao, Yuan Yuan; Bonnet, Sandra Breuils; Bonnet, Sebastien; Bowles, Dawn; Sutendra, Gopinath; Michelakis, Evangelos

TRIM35 Monoubiquitinates H2B in Cardiac Cells, Implications for Heart Failure

CIRCULATION RESEARCH

IF16.2

2024-07-05

PREAI

Lorenzana-Carrillo, Maria Areli; Tejay, Saymon; Nanoa, Joseph; Huang, Guocheng; Liu, Yongsheng; Haromy, Alois; Zhao, Yuan Yuan; Pla, Michelle Mendiola; Bowles, Dawn E.; Kinnaird, Adam; Michelakis, Evangelos D.; Sutendra, Gopinath

A Critical Contribution of Cardiac Myofibroblasts and a Predictive Role of UCP2 SNPs in the RV Decompensation in Pulmonary Hypertension

CIRCULATION

IF38.6

2023-11-07

PREAI

Zhang, Yongneng; Carrillo, Maria A. Lorenzana; Tejay, Saymon; Haromy, Alois S.; Liu, Yongsheng; Zhao, Yuan Yuan; Sutendra, Gopinath; Michelakis, Evangelos D.

TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-11-02

PREAI

Lorenzana-Carrillo, Maria Areli; Gopal, Keshav; Byrne, Nikole J.; Tejay, Saymon; Saleme, Bruno; Das, Subhash K.; Zhang, Yongneng; Haromy, Alois; Eaton, Farah; Pla, Michelle Mendiola; Bowles, Dawn E.; Dyck, Jason R. B.; Ussher, John R.; Michelakis, Evangelos D.; Sutendra, Gopinath

MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex

MOLECULAR CELL

IF16.6

2022-03-01

OAAI

Zervopoulos, Sotirios D.; Boukouris, Aristeidis E.; Saleme, Bruno; Haromy, Alois; Tejay, Saymon; Sutendra, Gopinath; Michelakis, Evangelos D.

A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

CELL REPORTS

IF6.9

2022-03-01

PREAI

Boukouris, Aristeidis E.; Zhang, Yongneng; Saleme, Bruno; Kinnaird, Adam; Zhao, Yuan Yuan; Liu, Yongsheng; Zervopoulos, Sotirios D.; Das, Subhash K.; Mittal, Rohan D.; Haromy, Alois; Lorenzana-Carrillo, Maria Areli; Krysler, Amanda R.; Cromwell, Christopher R.; Hubbard, Basil P.; Sutendra, Gopinath; Michelakis, Evangelos D.

SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2021-12-07

OAAI

Zhang, Yongneng; Zervopoulos, Sotirios D.; Boukouris, Aristeidis E.; Lorenzana-Carrillo, Maria Areli; Saleme, Bruno; Webster, Linda; Liu, Yongsheng; Haromy, Alois; Dakhili, Seyed Amirhossein Tabatabaei; Ussher, John R.; Sutendra, Gopinath; Michelakis, Evangelos D.

Myocardial Functional Decline During Prolonged Ex Situ Heart Perfusion

ANNALS OF THORACIC SURGERY

IF3.9

2019-08-01

OAAI

Hatami, Sanaz; White, Christopher W.; Shan, Shubham; Haromy, Alois; Qi, Xiao; Ondrus, Martin; Kinnear, Alexandra; Himmat, Sayed; Michelakis, Evangelos; Nagendran, Jayan; Freed, Darren H.

A Leukocyte Filter Does Not Provide Further Benefit During Ex Vivo Lung Perfusion 白细胞过滤器在离体肺灌注期间不能提供进一步的益处

ASAIO JOURNAL

IF2.3

2017-09-01

PREAI

Luc, Jessica G. Y.; Aboelnazar, Nader S.; Himmat, Sayed; Hatami, Sanaz; Haromy, Alois; Matsumura, Nobutoshi; Vasanthan, Vishnu; White, Christopher W.; Mengel, Michael; Freed, Darren H.; Nagendran, Jayan

Does a Leukocyte Filter Show Benefit in Ex-Vivo Lung Perfusion?

JOURNAL OF HEART AND LUNG TRANSPLANTATION

IF6

2016-04-01

OAAI

Luc, J. G.; Aboelnazar, N.; Hatami, S.; Haromy, A.; Vasanthan, V.; White, C. W.; Freed, D. H.; Nagendran, J.

A miR-208-Mef2 Axis Drives the Decompensation of Right Ventricular Function in Pulmonary Hypertension

CIRCULATION RESEARCH

IF16.2

2015-01-02

101

OAAI

Paulin, Roxane; Sutendra, Gopinath; Gurtu, Vikram; Dromparis, Peter; Haromy, Alois; Provencher, Steeve; Bonnet, Sebastien; Michelakis, Evangelos D.

Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans

CELL METABOLISM

IF30.9

2014-11-01

180

PREAI

Paulin, Roxane; Dromparis, Peter; Sutendra, Gopinath; Gurtu, Vikram; Zervopoulos, Sotirios; Bowers, Lyndsay; Haromy, Alois; Webster, Linda; Provencher, Steeve; Bonnet, Sebastien; Michelakis, Evangelos D.

Targeting cell motility in pulmonary arterial hypertension

EUROPEAN RESPIRATORY JOURNAL

IF21

2013-07-11

OAAI

Paulin, Roxane; Meloche, Jolyane; Courboulin, Audrey; Lambert, Caroline; Haromy, Alois; Courchesne, Antony; Bonnet, Pierre; Provencher, Steeve; Michelakis, Evangelos D.; Bonnet, Sebastien

Phosphatidylethanolamine Deficiency in Mammalian Mitochondria Impairs Oxidative Phosphorylation and Alters Mitochondrial Morphology

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-02-01

295

OAAI

Tasseva, Guergana; Bai, Helin Daniel; Davidescu, Magdalena; Haromy, Alois; Michelakis, Evangelos; Vance, Jean E.

Attenuating Endoplasmic Reticulum Stress as a Novel Therapeutic Strategy in Pulmonary Hypertension

CIRCULATION

IF38.6

2013-01-01

149

OAAI

Dromparis, Peter; Paulin, Roxane; Stenson, Trevor H.; Haromy, Alois; Sutendra, Gopinath; Michelakis, Evangelos D.

Mitochondrial activation by inhibition of PDKII suppresses HIF1α signaling and angiogenesis in cancer

ONCOGENE

IF7.3

2012-05-21

158

OAAI

Sutendra, G.; Dromparis, P.; Kinnaird, A.; Stenson, T. H.; Haromy, A.; Parker, J. M. R.; McMurtry, M. S.; Michelakis, E. D.

DICHLOROACETATE IS A NOVEL THERAPY FOR RENAL CELL CARCINOMA

JOURNAL OF UROLOGY

IF6.8

2012-04-01

PREAI

Kinnaird, Adam; Dromparis, Peter; Haromy, Alois; Bowers, Lyndsay; Hashimoto, Kyoko; Sutendra, Gopinath; Michelakis, Evangelos

The Role of Nogo and the Mitochondria-Endoplasmic Reticulum Unit in Pulmonary Hypertension

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2011-06-22

206

OAAI

Sutendra, Gopinath; Dromparis, Peter; Wright, Paulette; Bonnet, Sebastien; Haromy, Alois; Hao, Zhengrong; McMurtry, M. Sean; Michalak, Marek; Vance, Jean E.; Sessa, William C.; Michelakis, Evangelos D.

Fatty Acid Oxidation and Malonyl-CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2010-08-11

184

PREAI

Sutendra, Gopinath; Bonnet, Sebastien; Rochefort, Gael; Haromy, Alois; Folmes, Karalyn D.; Lopaschuk, Gary D.; Dyck, Jason R. B.; Michelakis, Evangelos D.

Metabolic Modulation of Glioblastoma with Dichloroacetate

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2010-05-12

665

PREAI

Michelakis, E. D.; Sutendra, G.; Dromparis, P.; Webster, L.; Haromy, A.; Niven, E.; Maguire, C.; Gammer, T. -L.; Mackey, J. R.; Fulton, D.; Abdulkarim, B.; McMurtry, M. S.; Petruk, K. C.

研究方向