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Evaluating Targeted Next-Generation Sequencing Assays and Reference Materials for NTRK Fusion Detection Chung, Christina Bormann; Lee, Jeeyun; Barritault, Marc; Bringuier, Pierre-Paul; Xu, Zhaolin; Huang, Weei-Yuarn; Beharry, Andrea; Castillo, Joseph; Christiansen, Jason; Lin, Jennifer C.; Sheffield, Brandon S. 分享 收藏
Detection of KRAS amplification on extrachromosomal DNA (ecDNA) upon acquired resistance to KRASG12C inhibitors Hansen, Ryan J.; Horton, Steven; Wiese, Julie; Bibay, BellJohn; Mora-Blanco, E. Lorena; Nguyen, Nam-Phuong; Engstrom, Lars D.; Briere, David M.; Calinisan, Andres; Olson, Peter; Awad, Mark M.; Aguirre, Andrew J.; Christiansen, Jason; Hassig, Christian; Kasibhatla, Shailaja 分享 收藏
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DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome Juratli, Tareq A.; McCabe, Devin; Nayyar, Naema; Williams, Erik A.; Silverman, Ian M.; Tummala, Shilpa S.; Fink, Alexandria L.; Baig, Aymen; Martinez-Lage, Maria; Selig, Martin K.; Bihun, Ivanna V.; Shankar, Ganesh M.; Penson, Tristan; Lastrapes, Matthew; Daubner, Dirk; Meinhardt, Matthias; Hennig, Silke; Kaplan, Alexander B.; Fujio, Shingo; Kuter, Benjamin M.; Bertalan, Mia S.; Miller, Julie J.; Batten, Julie M.; Ely, Heather A.; Christiansen, Jason; Baretton, Gustavo B.; Stemmer-Rachamimov, Anat O.; Santagata, Sandro; Rivera, Miguel N.; Barker, Fred G.; Schackert, Gabriele; Wakimoto, Hiroaki; Iafrate, A. John; Carter, Scott L.; Cahill, Daniel P.; Brastianos, Priscilla K. 分享 收藏
Mechanistic and pharmacodynamic characterization of the immuno-oncological activity of RXDX-106, a novel TYRO3, AXL, and MER (TAM) inhibitor in clinical development Albert, Amanda; Lew, Erin D.; Smith, Kristen; Tindall, Elizabeth A.; Yokoyama, Yumi; Diliberto, Amy; Ely, Heather; Lee, Jack; Nevarez, Robin; Oh, Joanne; Walsh, Colin; Christiansen, Jason; Li, Gary; Shoemaker, Robert 分享 收藏
RET fusions in a small subset of advanced colorectal cancers at risk of being neglected Pietrantonio, F.; Di Nicolantonio, F.; Schrock, A. B.; Lee, J.; Morano, F.; Fuca, G.; Nikolinakos, P.; Drilon, A.; Hechtman, J. F.; Christiansen, J.; Gowen, K.; Frampton, G. M.; Gasparini, P.; Rossini, D.; Gigliotti, C.; Kim, S. T.; Prisciandaro, M.; Hodgson, J.; Zaniboni, A.; Chiu, V. K.; Milione, M.; Patel, R.; Miller, V.; Bardelli, A.; Novara, L.; Wang, L.; Pupa, S. M.; Sozzi, G.; Ross, J.; Di Bartolomeo, M.; Bertotti, A.; Ali, S.; Trusolino, L.; Falcone, A.; de Braud, F.; Cremolini, C. 分享 收藏
ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms Couts, Kasey L.; Bemis, Judson; Turner, Jacqueline A.; Bagby, Stacey M.; Murphy, Danielle; Christiansen, Jason; Hintzsche, Jennifer D.; Le, Anh; Pitts, Todd M.; Wells, Keith; Applegate, Allison; Amato, Carol; Multani, Pratik; Chow-Maneval, Edna; Tentler, John J.; Shellman, Yiqun G.; Rioth, Matthew J.; Tan, Aik-Choon; Gonzalez, Rene; Medina, Theresa; Doebele, Robert C.; Robinson, William A. 分享 收藏
Characterizing and targeting RET fusions-positive metastatic colorectal cancer (mCRC) Morano, Federica; Schrock, Alexa; Lee, Jeeyun; Nikolinakos, Petros; Drilon, Alexander; Christiansen, Jason; Chiu, Vi; Zaniboni, Alberto; Rossini, Daniele; Kim, Seung Tae; Milione, Massimo; Patel, Rupal; Miller, Vincet; Corallo, Salvatore; Di Bartolomeo, Maria; Ross, Jeffrey; Bertotti, Andrea; Bardelli, Alberto; Di Nicolantonio, Federica; Ali, Siraj; Trusolino, Livio; Falcone, Alfredo; de Braud, Filippo; Cremolini, Chiara; Pietrantonio, Filippo 分享 收藏
Activity of Entrectinib in a Patient With the First Reported NTRK Fusion in Neuroendocrine Cancer Sigal, Darren; Tartar, Marie; Xavier, Marin; Bao, Fei; Foley, Patrick; Luo, David; Christiansen, Jason; Hornby, Zachary; Maneval, Edna Chow; Multani, Pratik 分享 收藏
Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance Giltnane, Jennifer M.; Hutchinson, Katherine E.; Stricker, Thomas P.; Formisano, Luigi; Young, Christian D.; Estrada, Monica V.; Nixon, Mellissa J.; Du, Liping; Sanchez, Violeta; Ericsson, Paula Gonzalez; Kuba, Maria G.; Sanders, Melinda E.; Mu, Xinmeng J.; Van Allen, Eliezer M.; Wagle, Nikhil; Mayer, Ingrid A.; Abramson, Vandana; Gomez, Henry; Rizzo, Monica; Toy, Weiyi; Chandarlapaty, Sarat; Mayer, Erica L.; Christiansen, Jason; Murphy, Danielle; Fitzgerald, Kerry; Wang, Kai; Ross, Jeffrey S.; Miller, Vincent A.; Stephens, Phillip J.; Yelensky, Roman; Garraway, Levi; Shyr, Yu; Meszoely, Ingrid; Balko, Justin M.; Arteaga, Carlos L. 分享 收藏
ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer Pietrantonio, Filippo; Di Nicolantonio, Federica; Schrock, Alexa B.; Lee, Jeeyun; Tejpar, Sabine; Sartore-Bianchi, Andrea; Hechtman, Jaclyn F.; Christiansen, Jason; Novara, Luca; Tebbutt, Niall; Fuca, Giovanni; Antoniotti, Carlotta; Kim, Seung Tae; Murphy, Danielle; Berenato, Rosa; Morano, Federica; Sun, James; Min, Bosun; Stephens, Philip J.; Chen, Marissa; Cremolini, Chiara 分享 收藏
Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1) Drilon, Alexander; Siena, Salvatore; Ou, Sai-Hong Ignatius; Patel, Manish; Ahn, Myung Ju; Lee, Jeeyun; Bauer, Todd M.; Farago, Anna F.; Wheler, Jennifer J.; Liu, Stephen V.; Doebele, Robert; Giannetta, Laura; Cerea, Giulio; Marrapese, Giovanna; Schirru, Michele; Amatu, Alessio; Bencardino, Katia; Palmeri, Laura; Sartore-Bianchi, Andrea; Vanzulli, Angelo; Cresta, Sara; Damian, Silvia; Duca, Matteo; Ardini, Elena; Li, Gang; Christiansen, Jason; Kowalski, Karey; Johnson, Ann D.; Patel, Rupal; Luo, David; Chow-Maneval, Edna; Hornby, Zachary; Multani, Pratik S.; Shaw, Alice T.; De Braud, Filippo G. 分享 收藏
RXDX-105 demonstrates anti-tumor efficacy in multiple preclinical cancer models driven by molecular alterations in RET or BRAF oncogenes Martin, L.; Walsh, C.; Uryu, S.; Joseph, J.; Franovic, A.; Schairer, A.; Patel, R.; Shoemaker, R.; Diliberto, A.; Murphy, D.; Christiansen, J.; Oliver, J.; Kowack, E.; Multani, P.; Li, G. G. 分享 收藏
Entrectinib, a highly potent pan-Trk; ROS1, and ALK inhibitor, has broad-spectrum, histology-agnostic anti-tumor activity in molecularly defined cancers Wei, G.; Patel, R.; Walsh, C.; Barrera, M.; Fagan, P.; Murphy, D.; Christiansen, J.; Shoemaker, R.; Hornby, Z.; Li, G. G. 分享 收藏
Improved efficacy response attributed to diagnostic selection - Interim results of the phase 1 experience from ALKA-372-001 Christiansen, J.; Siena, S.; Valtorta, E.; Johnson, A.; Murphy, D.; Shoemaker, R.; Lamoureux, J.; Luo, D.; Patel, R.; Hornby, Z.; Multani, P.; Maneval, E. Chow; Duca, M.; Debraud, F. 分享 收藏
A novel, statistical-based method to determine RNA expression by next-generation sequencing in clinical FFPE samples Shoemaker, Robert; Berlin, Aaron; Diliberto, Amy; Ely, Heather; Chen, Marissa; Murphy, Danielle; Christiansen, Jason; Reuter, Vince; Licon, Abel 分享 收藏
What hides behind the MASC: clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC) Drilon, A.; Li, G.; Dogan, S.; Gounder, M.; Shen, R.; Arcila, M.; Wang, L.; Hyman, D. M.; Hechtman, J.; Wei, G.; Cam, N. R.; Christiansen, J.; Luo, D.; Maneval, E. C.; Bauer, T.; Patel, M.; Liu, S. V.; Ou, S. H. I.; Farago, A.; Shaw, A.; Shoemaker, R. F.; Lim, J.; Hornby, Z.; Multani, P.; Ladanyi, M.; Berger, M.; Katabi, N.; Ghossein, R.; Ho, A. L. 分享 收藏
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