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Common variants increase risk for congenital diaphragmatic hernia within the context of de novo variants 在新生变异的背景下,常见变异会增加先天性diaphragm肌疝的风险 Qiao, Lu; Welch, Carrie L.; Hernan, Rebecca; Wynn, Julia; Krishnan, Usha S.; Zalieckas, Jill M.; Buchmiller, Terry; Khlevner, Julie; De, Aliva; Farkouh-Karoleski, Christiana; Wagner, Amy J.; Heydweiller, Andreas; Mueller, Andreas C.; de Klein, Annelies; Warner, Brad W.; Maj, Carlo; Chung, Dai; McCulley, David J.; Schindel, David; Potoka, Douglas; Fialkowski, Elizabeth; Schulz, Felicitas; Kipfmuller, Florian; Lim, Foong-Yen; Magielsen, Frank; Mychaliska, George B.; Aspelund, Gudrun; Reutter, Heiko Martin; Needelman, Howard; Schnater, J. Marco; Fisher, Jason C.; Azarow, Kenneth; Elfiky, Mahmoud; Noethen, Markus M.; Danko, Melissa E.; Li, Mindy; Kosinski, Przemyslaw; Wijnen, Rene M. H.; Cusick, Robert A.; Soffer, Samuel Z.; Cochius-Den Otter, Suzan C. M.; Schaible, Thomas; Crombleholme, Timothy; Duron, Vincent P.; Donahoe, Patricia K.; Sun, Xin; High, Frances A.; Bendixen, Charlotte; Brosens, Erwin; Shen, Yufeng; Chung, Wendy K. 分享 收藏
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WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines Bumpous, Leigh A.; Moe, Kylie C.; Wang, Jing; Carver, Logan A.; Williams, Alexandria G.; Romer, Alexander S.; Scobee, Jesse D.; Maxwell, Jack N.; Jones, Cheyenne A.; Chung, Dai H.; Tansey, William P.; Liu, Qi; Weissmiller, April M. 分享 收藏
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Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene Qiao, Lu; Xu, Le; Yu, Lan; Wynn, Julia; Hernan, Rebecca; Zhou, Xueya; Farkouh-Karoleski, Christiana; Krishnan, Usha S.; Khlevner, Julie; De, Aliva; Zygmunt, Annette; Crombleholme, Timothy; Lim, Foong-Yen; Needelman, Howard; Cusick, Robert A.; Mychaliska, George B.; Warner, Brad W.; Wagner, Amy J.; Danko, Melissa E.; Chung, Dai; Potoka, Douglas; Kosinski, Przemyslaw; McCulley, David J.; Elfiky, Mahmoud; Azarow, Kenneth; Fialkowski, Elizabeth; Schindel, David; Soffer, Samuel Z.; Lyon, Jane B.; Zalieckas, Jill M.; Vardarajan, Badri N.; Aspelund, Gudrun; Duron, Vincent P.; High, Frances A.; Sun, Xin; Donahoe, Patricia K.; Shen, Yufeng; Chung, Wendy K. 分享 收藏
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Likely damaging de novo variants in congenital diaphragmatic hernia patients are associated with worse clinical outcomes 先天性diaphragm肌疝患者可能具有破坏性的从头变异与较差的临床结局相关 Qiao, Lu; Wynn, Julia; Yu, Lan; Hernan, Rebecca; Zhou, Xueya; Duron, Vincent; Aspelund, Gudrun; Farkouh-Karoleski, Christiana; Zygumunt, Annette; Krishnan, Usha S.; Nees, Shannon; Khlevner, Julie; Lim, Foong Yen; Crombleholme, Timothy; Cusick, Robert; Azarow, Kenneth; Danko, Melissa Ellen; Chung, Dai; Warner, Brad W.; Mychaliska, George B.; Potoka, Douglas; Wagner, Amy J.; Soffer, Samuel; Schindel, David; McCulley, David J.; Shen, Yufeng; Chung, Wendy K. 分享 收藏
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WDR5 is a conserved regulator of protein synthesis gene expression Bryan, Audra F.; Wang, Jing; Howard, Gregory C.; Guarnaccia, Alissa D.; Woodley, Chase M.; Aho, Erin R.; Rellinger, Eric J.; Matlock, Brittany K.; Flaherty, David K.; Lorey, Shelly L.; Chung, Dai H.; Fesik, Stephen W.; Liu, Qi; Weissmiller, April M.; Tansey, William P. 分享 收藏