Gerard P. Zambetti - Publications, H-index & Citations

Gerard P. Zambetti

St Jude Children's Research Hospital

65H指数

321论文数

2.1W被引数

收录论文 83

发表时间

Validation of DNA methylation subtype as a prognostic biomarker in pediatric adrenocortical tumors: re-evaluation of results from the COG ARAR0332 clinical trial DNA甲基化亚型作为儿童肾上腺皮质肿瘤预后生物标志物的验证：对COG ARAR0332临床试验结果的重新评估

npj Precision Oncology

IF8

2026-07-23

OAAI

Michael R. Clay; Quynh T. Tran; Emilia M. Pinto; Tong Lin; Allison F. O’Neill; Md. Zahangir Alom; Ruobing Zhou; Mark D. Krailo; Raul C. Ribeiro; Gerard P. Zambetti; Stanley Pounds; Carlos Rodríguez-Galindo; Brent A. Orr

A quantitative, Bayesian-informed approach to gene-specific variant classification: Updated Expert Panel recommendations improve classification of TP53 germline variants for Li-Fraumeni syndrome 一种基于贝叶斯定量分析的基因特异性变异分类方法：更新的专家小组建议改进了TP53生殖细胞变异在Li-Fraumeni综合征中的分类

Genome Medicine

IF11.2

2025-10-24

OAAI

Cristina Fortuno; Megan N. Frone; Jessica Mester; Miguel de la Hoya; Phuong L. Mai; Tina Pesaran; Maria Isabel Achatz; Rebecca Bassett; Carolina Bustamante; Stephanie Crowley; Kelvin Cesar de Andrade; D. Gareth Evans; Bingjian Feng; Laura Fuqua; Maria Isabel Harrell; Jessica N. Hatton; Robert Huether; Chimene Kesserwan; Kristy Lee; Suzanne P. MacFarland; Jamie L. Maciaszek; Kara Maxwell; Kelly McGoldrick; Maureen Murphy; Bita Nehoray; Judith Penkert; Emilia Modolo Pinto; Sharon E. Plon; Alison Schwartz-Levine; Ashley S. Thompson; Wenyi Wang; Gerard P. Zambetti; Kristin Zelley; Paul A. James; Sharon A. Savage; Christian P. Kratz; Amanda B. Spurdle

TERT c.3150 G > C (p.K1050N): a founder Ashkenazi Jewish variant associated with telomere biology disorders TERT c.3150 g > °c (p.K1050N): 与端粒生物学疾病相关的创始人Ashkenazi犹太人变体

npj Genomic Medicine

IF4.8

2025-06-02

OAAI

Kelvin César de Andrade; Emilia M. Pinto; Tianna Zhao; Logan P. Zeigler; Jung Kim; Neelam Giri; Jeremy S. Haley; Lisa J. McReynolds; Oscar Florez-Vargas; Aaron H. Phillips; Richard W. Kriwacki; Sherifa A. Akinniyi; Scott B. Cohen; Matthew R. Emerson; Diane T. Smelser; Gretchen M. Urban; Cintia Fridman; Gerard P. Zambetti; Tracy M. Bryan; David J. Carey; Christine Kim Garcia; Douglas R. Stewart; Sharon A. Savage

Cancer associated to low-penetrance TP53 variants: insights from p.R337H 与低外显率TP53变异相关的癌症：来自p.R337H的见解

Trends in Cancer

IF17.5

2025-04-22

PREAI

Enzo Lalli; Gerard P. Zambetti; Raul C. Ribeiro; Bonald C. Figueiredo

Multiple TP53 p.R337H haplotypes and implications for tumor susceptibility

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2024-01-01

OAAI

Pinto, Emilia M.; Fridman, Cintia; Figueiredo, Bonald C.; Salvador, Hector; Teixeira, Manuel R.; Pinto, Carla; Pinheiro, Manuela; Kratz, Christian P.; Lavarino, Cinzia; Legal, Edith A. M. F.; Le, Anh; Kelly, Gregory; Koeppe, Erika; Stoffel, Elena M.; Breen, Kelsey; Hahner, Stefanie; Heinze, Britta; Techavichit, Piti; Krause, Amanda; Ogata, Tsutomu; Fujisawa, Yasuko; Walsh, Michael F.; Rana, Huma Q.; Maxwell, Kara N.; Garber, Judy E.; Rodriguez-Galindo, Carlos; Ribeiro, Raul C.; Zambetti, Gerard P.

Oncogenic Cells of Renal Embryonic Lineage Sensitive to the Small-Molecule Inhibitor QC6352 Display Depletion of KDM4 Levels and Disruption of Ribosome Biogenesis

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-11-21

OAAI

Pichavaram, Prahalathan; Jablonowski, Carolyn M.; Fang, Jie; Fleming, Andrew M.; Gil, Hyea Jin; Boghossian, Andrew S.; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Morton, Christopher L.; Zambetti, Gerard P.; Davidoff, Andrew M.; Yang, Jun; Murphy, Andrew J.

B7-H3-CAR T cells for the treatment of pediatric adrenocortical carcinoma

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Epperly, Rebecca; Pinto, Emilia M.; Santiago, Teresa; Sheppard, Heather; Clay, Michael R.; Morton, Christopher; Nguyen, Phuong; Zhou, Yinmei; Woolard, Mary; O'Reilly, Carla; Justice, Julie; Akers, Walter; Johnson, Melissa; Karlstrom, Asa; Cheng, Cheng; Zambetti, Gerard; Davidoff, Andrew; Ribeiro, Raul; DeRenzo, Christopher

E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

106

OAAI

Nip, J; Strom, DK; Fee, BE; Zambetti, G; Cleveland, JL; Hiebert, SW

Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressor

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

157

OAAI

Wang, QJ; Zambetti, GP; Suttle, DP

Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

200

OAAI

Frazier, MW; He, XP; Wang, JL; Gu, ZM; Cleveland, JL; Zambetti, GP

Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Wen, RR; Wang, DM; McKay, C; Bunting, KD; Marine, JC; Vanin, EF; Zambetti, GP; Korsmeyer, SJ; Ihle, JN; Cleveland, JL

p53 binds selectively to the 5′ untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor β- and p53-mediated translational inhibition of cdk4

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Miller, SJ; Suthiphongchai, T; Zambetti, GP; Ewen, ME

ei24, a p53 response gene involved in growth suppressio and apoptosis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

118

OAAI

Gu, ZM; Flemington, C; Chittenden, T; Zambetti, GP

Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

132

OAAI

Garrison, Sean P.; Jeffers, John R.; Yang, Chunying; Nilsson, Jonas A.; Hall, Mark A.; Rehg, Jerold E.; Yue, Wen; Yu, Jian; Zhang, Lin; Onciu, Mihaela; Sample, Jeffery T.; Cleveland, John L.; Zambetti, Gerard P.

Clinical and Functional Significance of TP53 Exon 4-Intron 4 Splice Junction Variants

MOLECULAR CANCER RESEARCH

IF4.7

2022-02-03

OAAI

Pinto, Emilia M.; Maxwell, Kara N.; Halalsheh, Hadeel; Phillips, Aaron; Powers, Jacquelyn; MacFarland, Suzanne; Walsh, Michael F.; Breen, Kelsey; Formiga, Maria N.; Kriwacki, Richard; Nichols, Kim E.; Mostafavi, Roya; Wang, Jinling; Clay, Michael R.; Rodriguez-Galindo, Carlos; Ribeiro, Raul C.; Zambetti, Gerard P.

Adrenocortical Tumors in Children With Constitutive Chromosome 11p15 Paternal Uniparental Disomy: Implications for Diagnosis and Treatment

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2021-11-05

OAAI

Pinto, Emilia Modolo; Rodriguez-Galindo, Carlos; Lam, Catherine G.; Ruiz, Robert E.; Zambetti, Gerard P.; Ribeiro, Raul C.

KDM6B Inhibition Has Anti-Tumor Activity in Anaplastic Wilms Tumor Cells Associated with WT1 And MYCN Pathway Silencing

PEDIATRICS

IF6.4

2021-03-01

PREAI

Gil, Hyea Jin; Pinto, Emilia M.; Davidoff, Andrew M.; Zambetti, Gerard P.; Yang, Jun; Murphy, Andrew J.

The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model

CANCER RESEARCH

IF16.6

2021-02-26

OAAI

Jeffers, John R.; Pinto, Emilia M.; Rehg, Jerold E.; Clay, Michael R.; Wang, Jinling; Neale, Geoffrey; Heath, Richard J.; Lozano, Guillermina; Lalli, Enzo; Figueiredo, Bonald C.; Pappo, Alberto S.; Rodriguez-Galindo, Carlos; Chen, Wenan; Pounds, Stanley; Ribeiro, Raul C.; Zambetti, Gerard P.

A Rare TP53 Mutation Predominant in Ashkenazi Jews Confers Risk of Multiple Cancers

CANCER RESEARCH

IF16.6

2020-09-02

OAAI

Powers, Jacquelyn; Pinto, Emilia M.; Barnoud, Thibaut; Leung, Jessica C.; Martynyuk, Tetyana; Kossenkov, Andrew, V; Philips, Aaron H.; Desai, Heena; Hausler, Ryan; Kelly, Gregory; Le, Anh N.; Li, Marilyn M.; MacFarland, Suzanne P.; Pyle, Louise C.; Zelley, Kristin; Nathanson, Katherine L.; Domchek, Susan M.; Slavin, Thomas P.; Weitzel, Jeffrey N.; Stopfer, Jill E.; Garber, Judy E.; Joseph, Vijai; Offit, Kenneth; Dolinsky, Jill S.; Gutierrez, Stephanie; McGoldrick, Kelly; Couch, Fergus J.; Levin, Brooke; Edelman, Morris C.; Levy, Carolyn Fein; Spunt, Sheri L.; Kriwacki, Richard W.; Zambetti, Gerard P.; Ribeiro, Raul C.; Murphy, Maureen E.; Maxwell, Kara N.

What 20 years of research has taught us about theTP53p.R337H mutation

CANCER

IF5.1

2020-08-17

OAAI

Pinto, Emilia Modolo; Zambetti, Gerard R.

研究方向