Phylip Chen - Publications, H-index & Citations

Phylip Chen

abigail wexner research institute at nationwide childrens hospital

9H指数

32论文数

540被引数

收录论文 20

发表时间

Intron retention regulates STAT2 function and associates with immunotherapy response in lung cancer 内含子保留调控STAT2功能并与肺癌免疫治疗反应相关

Science

IF45.8

2026-10-22

PREAI

Ryan P. Englander; Mattia Brugiolo; Maëva Devoucoux; Te-Chia Wu; Mitch Kostich; Nathan K. Leclair; Isha Walawalkar; Hyeon Gu Kang; SungHee Park; Florentina Marches; Mark E. Peeples; Phylip Chen; Jacques Banchereau; Peter Yu; Andrew Salner; Romain Banchereau; Karolina Palucka; Olga Anczuków

A rapid yeast-based reverse genetics system reveals SARS-CoV-2 Omicron BA.2.86 variant spreads faster than Omicron JN.1 variant in primary human nasal and bronchial epithelial airway cultures 一种快速酵母基反向遗传学系统揭示奥密克戎BA.2.86变种在原代人鼻和支气管上皮气道培养物中比奥密克戎JN.1变种传播更快

mBio

IF4.7

2026-06-10

PREAI

Xu, Jiayu; Chamblee, Michelle; Hsu, Cheng Chih; Jiang, Fei; Chen, Phylip; Zhang, Yuexiu; Liang, Xueya; Amer, Amal O.; Boyaka, Prosper N.; Cormet-Boyaka, Estelle; Peeples, Mark E.; Li, Jianrong

Neuregulin-1 reduces human airway epithelium permeability caused by respiratory viral infection through HER-2

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Hussain, Syed-Rehan A.; Chen, Phylip; Bochter, Mathew S.; Rohlfing, Michelle; Peeples, Mark E.; Grayson, Mitchell H.

Cytokine responses to respiratory syncytial virus infection in well-differentiated infant nasal epithelial cell cultures 细胞因子对呼吸道合胞病毒感染的反应在良好分化的婴儿鼻上皮细胞培养物中

CLINICAL AND EXPERIMENTAL VACCINE RESEARCH

IF0

2025-10-01

OAAI

Yun, Ki Wook; Chen, Phylip; Reynolds, Susan D.; Mejias, Asuncion; Peeples, Mark E.; Ramilo, Octavio

Development of SARS-CoV-2 as a viral vector: A novel intranasal bivalent vaccine for SARS-CoV-2 and RSV SARS-CoV-2作为病毒载体的发展：一种新型的鼻内双价SARS-CoV-2和RSV疫苗

Science Advances

IF12.5

2025-09-26

OAAI

Jiayu Xu; Michelle Chamblee; Fei Jiang; Mahesh KC; Cheng Chih Hsu; Ilada Thongpan; Phylip Chen; Yuexiu Zhang; Chun-Ta Chiu; Mohamed M. Shamseldin; Heba M. Amer; Xueya Liang; Amal O. Amer; Prosper N. Boyaka; Estelle Cormet-Boyaka; Mark E. Peeples; Jianrong Li

A ventilated perfused lung model platform to dissect the response of the lungs to viral infection 一种通气血流灌注的肺模型平台，用于解析肺部对病毒感染的应答

Trends in Biotechnology

IF14.9

2025-04-24

PREAI

I. Deniz Derman; Mecit Altan Alioglu; Joseph Christakiran Moses; Zissis C. Chroneos; Yasar Ozer Yilmaz; Dishary Banerjee; Jonathan Koff; Syed Hasan Askari Rizvi; Danielle Nicole Klunk; Nazmiye Celik; Sirisha Pochareddy; Todd M. Umstead; Ilayda Namli; Sarah E. Holton; Carmen Mikacenic; Jessica L. Thompson; Diana Cadena Castaneda; Danielle Reifsnyder Hickey; Momoka Nagamine; Prajakta Warang; Michael Schotsaert; Phylip Chen; Mark E. Peeples; Karolina Palucka; Ibrahim T. Ozbolat

Neuregulin-1 prevents death from a normally lethal respiratory viral infection

PLOS PATHOGENS

IF4.9

2025-04-01

OAAI

Hussain, Syed-Rehan A.; Rohlfing, Michelle; Santoro, Jennifer; Chen, Phylip; Muralidharan, Kaushik; Bochter, Matthew S.; Peeples, Mark E.; Grayson, Mitchell H.

Coumarins and Hesperetin Inhibit Human Respiratory Syncytial Virus Infection 香豆素和Hesperetin抑制人呼吸道合胞病毒感染

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2024-12-11

OAAI

de Sa, Jessica Marostica; Thongpan, Ilada; Busso, Jefferson de Souza; Rodrigues, Thaina dos Santos; Chen, Phylip; Helena, Alvaro Luiz; Regasini, Luis Octavio; Fossey, Marcelo Andres; Caruso, icaro Putinhon; de Souza, Fatima Pereira; Peeples, Mark Edward

High-throughput bioprinting of the nasal epithelium using patient-derived nasal epithelial cells

BIOFABRICATION

IF8

2023-08-14

OAAI

Derman, I. Deniz; Yeo, Miji; Castaneda, Diana Cadena; Callender, Megan; Horvath, Mian; Mo, Zengshuo; Xiong, Ruoyun; Fleming, Elizabeth; Chen, Phylip; Peeples, Mark E.; Palucka, Karolina; Oh, Julia; Ozbolat, Ibrahim T.

Architecture and matrix assembly determinants of Bordetella pertussis biofilms on primary human airway epithelium

PLOS PATHOGENS

IF4.9

2023-02-23

OAAI

Fullen, Audra R.; Gutierrez-Ferman, Jessica L.; Rayner, Rachael E.; Kim, Sun Hee; Chen, Phylip; Dubey, Purnima; Wozniak, Daniel J.; Peeples, Mark E.; Cormet-Boyaka, Estelle; Deora, Rajendar

5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons 5-甲基胞嘧啶 (m5C) RNA修饰通过调节I型干扰素来控制对病毒感染的先天免疫反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-10-14

OAAI

Zhang, Yuexiu; Zhang, Li-Sheng; Dai, Qing; Chen, Phylip; Lu, Mijia; Kairis, Elizabeth L.; Murugaiah, Valarmathy; Xu, Jiayu; Shukla, Rajni Kant; Liang, Xueya; Zou, Zhongyu; Cormet-Boyaka, Estelle; Qiu, Jianming; Peeples, Mark E.; Sharma, Amit; He, Chuan; Li, Jianrong

Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus

PLOS PATHOGENS

IF4.9

2021-12-20

OAAI

Xue, Miaoge; Zhang, Yuexiu; Wang, Haitao; Kairis, Elizabeth L.; Lu, Mijia; Ahmad, Sadeem; Attia, Zayed; Harder, Olivia; Zhang, Zijie; Wei, Jiangbo; Chen, Phylip; Gao, Youling; Peeples, Mark E.; Sharma, Amit; Boyaka, Prosper; He, Chuan; Hur, Sun; Niewiesk, Stefan; Li, Jianrong

A Novel Live Attenuated Respiratory Syncytial Virus Vaccine Candidate with Mutations in the L Protein SAM Binding Site and the G Protein Cleavage Site Is Protective in Cotton Rats and a Rhesus Macaque

JOURNAL OF VIROLOGY

IF3.8

2021-01-13

OAAI

Jenkins, Tiffany; Wang, Rongzhang; Harder, Olivia; Xue, Miaoge; Chen, Phylip; Corry, Jacqueline; Walker, Christopher; Teng, Michael; Mejias, Asuncion; Ramilo, Octavio; Niewiesk, Stefan; Li, Jianrong; Peeples, Mark E.

Stable Attenuation of Human Respiratory Syncytial Virus for Live Vaccines by Deletion and Insertion of Amino Acids in the Hinge Region between the mRNA Capping and Methyltransferase Domains of the Large Polymerase Protein

JOURNAL OF VIROLOGY

IF3.8

2020-11-23

OAAI

Xue, Miaoge; Wang, Rongzhang; Harder, Olivia; Chen, Phylip; Lu, Mijia; Cai, Hui; Li, Anzhong; Liang, Xueya; Jennings, Ryan; La Perle, Krista; Niewiesk, Stefan; Peeples, Mark E.; Li, Jianrong

Mathematical modelling identifies the role of adaptive immunity as a key controller of respiratory syncytial virus in cotton rats 数学模型确定了适应性免疫作为棉鼠呼吸道合胞病毒的关键控制者的作用

JOURNAL OF THE ROYAL SOCIETY INTERFACE

IF3.5

2019-11-27

OAAI

Wethington, Darren; Harder, Olivia; Uppulury, Karthik; Stewart, William C. L.; Chen, Phylip; King, Tiffany; Reynolds, Susan D.; Perelson, Alan S.; Peeples, Mark E.; Niewiesk, Stefan; Das, Jayajit

Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

NATURE COMMUNICATIONS

IF15.7

2019-10-09

OAAI

Xue, Miaoge; Zhao, Boxuan Simen; Zhang, Zijie; Lu, Mijia; Harder, Olivia; Chen, Phylip; Lu, Zhike; Li, Anzhong; Ma, Yuanmei; Xu, Yunsheng; Liang, Xueya; Zhou, Jiyong; Niewiesk, Stefan; Peeples, Mark E.; He, Chuan; Li, Jianrong

Importance of Ras signaling in EphB2-mediated ependymoma development

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Johnson, Robert A.; Chen, Phylip; Lyons, Robert; Priddy, Samuel

EphB2 activation is required for ependymoma development as well as inhibits differentiation and promotes proliferation of the transformed cell

SCIENTIFIC REPORTS

IF3.9

2015-03-24

OAAI

Chen, Phylip; Rossi, Nathan; Priddy, Samuel; Pierson, Christopher R.; Studebaker, Adam W.; Johnson, Robert A.