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PHARMACOKINETICS, PHARMACODYNAMICS AND CLINICAL DATA UPDATE FROM PHASE 0/1 TRIAL FOR BDTX-1535 IN RECURRENT GLIOBLASTOMA PATIENTS WITH EGFR ALTERATIONS. BDTX-1535在EGFR发生变异的复发性胶质母细胞瘤患者中，来自第0/1期试验的药代动力学、药效动力学及临床数据更新。 Sanai, N.; Umemura, Y.; Karapetyan, V; Margaryan, T.; Huttenlocher, D.; Pham, B.; Harmon, J.; Hong, A.; Yoo, W.; Tien, A.; Tovmasyan, A.; Mehta, S. 分享 收藏
A CLINICAL UPDATE OF A FIRST-IN-HUMAN PHASE 0/1 TRIAL OF 5-AMINOLEVULINIC ACID SONODYNAMIC THERAPY (5-ALA SDT) IN RECURRENT GLIOBLASTOMA. 5-氨基乙酰丙酸声动力疗法(5-ALA SDT)在复发性胶质母细胞瘤中的首个人类临床试验0/1期临床更新。 Sanai, N.; Tien, A.; Tovmasyan, A.; Chang, Y.; Margaryan, T.; Hendrickson, K.; Eschbacher, J.; Yoo, W.; Harmon, J.; Hong, A.; Quarles, C.; Alhilali, L.; Barani, I; Mirzadeh, Z.; Mehta, S. 分享 收藏
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A PHASE 0/1B STUDY OF AZD1390 PLUS RADIOTHERAPY IN NEWLY DIAGNOSED, MGMT-UNMETHYLATED AND RECURRENT GLIOBLASTOMA PATIENTS Sanai, Nader; Umemura, Yoshie; Desai, Siddhi; Margaryan, Tigran; Molloy, Jennifer; Locascio, Costanza; Elliott, Mackenna; Harmon, Jocelyn; Hong, Amy; Melendez, Ernesto Luna; Wanebo, John; Braun, Kelly; Kennedy, William R.; Garcia, Michael; Yoo, Wonsuk; Tovmasyan, Artak; Tien, An-Chi; Mehta, Shwetal 分享 收藏
A PHASE 0/2 TRIAL OF ABEMACICLIB PLUS LY3214996 IN RECURRENT GLIOBLASTOMA Sanai, Nader; Umemura, Yoshie; Chang, Yu-Wei; Margaryan, Tigran; Desantis, Anita; Elliott, Mackenna; Molloy, Jennifer; Huttenlocher, Dylan; Hook, Garry; Yoo, Wonsuk; Tien, An-Chi; Tovmasyan, Artak; Mehta, Shwetal 分享 收藏
A PHASE 0/1 STUDY OF BDTX-1535 IN RECURRENT GLIOBLASTOMA (GBM) PATIENTS WITH EGFR ALTERATIONS OR FUSIONS Sanai, Nader; Umemura, Yoshie; Karapetyan, Vahuni; Margaryan, Tigran; Huttenlocher, Dylan; Harmon, Jocelyn; Hong, Amy; Yoo, Wonsuk; Tien, An-Chi; Tovmasyan, Artak; Mehta, Shwetal 分享 收藏
CLINICAL EFFICACY AND PK/PD RESPONSE IN A PHASE 0/2 STUDY OF NIRAPARIB PLUS RADIOTHERAPY FOR NEWLY-DIAGNOSED, MGMT-UNMETHYLATED GLIOBLASTOMA Sanai, Nader; Umemura, Yoshie; Margaryan, Tigran; Molloy, Jennifer; Zhang, Hualin; Knight, William; Harmon, Jocelyn; Hong, Amy; Wanebo, John; Braun, Kelly; Kennedy, William R.; Garcia, Michael; Barani, Igor; Yoo, Wonsuk; Tien, An-Chi; Tovmasyan, Artak; Mehta, Shwetal 分享 收藏
A PHASE 0/1B STUDY OF AZD1390 PLUS RADIOTHERAPY IN RECURRENT GLIOBLASTOMA PATIENTS Sanai, N.; Umemura, Y.; Desai, S.; Margaryan, T.; Molloy, J.; Lo Cascio, C.; Elliott, M.; Harmon, J.; Hong, A.; Melendez, E. Luna; Wanebo, J.; Braun, K.; Kennedy, W.; Garcia, M.; Yoo, W.; Tovmasyan, A.; Tien, A.; Mehta, S. 分享 收藏
A NIRAPARIB EFFICACY IN PATIENTS WITH NEWLY-DIAGNOSED GLIOBLASTOMA: CLINICAL READOUT OF A PHASE 0/2 'TRIGGER' TRIAL Sanai, N.; Umemura, Y.; Margaryan, T.; Molloy, J.; Zhang, H.; Knight, W.; Harmon, J.; Hong, A.; Wanebo, J.; Braun, K.; Kennedy, W.; Garcia, M.; Barani, I.; Yoo, W.; Tien, A.; Tovmasyan, A.; Mehta, S. 分享 收藏
A PHASE 0/1 'TRIGGER' TRIAL OF BDTX-1535 IN RECURRENT HIGH-GRADE GLIOMA (HGG) PATIENTS WITH EGFR ALTERATIONS OR FUSIONS Sanai, N.; Umemura, Y.; Karapetyan, V.; Margaryan, T.; Huttenlocher, D.; Harmon, J.; Hong, A.; Yoo, W.; Tien, A.; Tovmasyan, A.; Mehta, S. 分享 收藏
A phase 0/1b study of AZD1390 plus radiotherapy in newly-diagnosed, MGMT-unmethylated glioblastoma patients Sanai, Nader; Desai, Siddhi; Margaryan, Tigran; Molloy, Jennifer; LoCascio, Costanza; Elliott, Mackenna; Harmon, Jocelyn; Hong, Amy; Melendez, Ernesto Luna; Wanebo, John; Braun, Kelly; Kennedy, William; Garcia, Michael; Yoo, Wonsuk; Tovmasyan, Artak; Tien, An-Chi; Mehta, Shwetal 分享 收藏
A phase 0/2 'trigger' trial of pamiparib or olaparib plus radiotherapy in patients with newly-diagnosed or recurrent glioblastoma Sanai, Nader; Chang, Yu-Wei; Jiang, Jun; Molloy, Jennifer; Pennington-Krygier, Chelsea; Harmon, Jocelyn; Hong, Amy; Wanebo, John; Kennedy, William; Garcia, Michael; Barani, Igor; Yoo, Wonsuk; Tovmasyan, Artak; Tien, An-Chi; Li, Jing; Mehta, Shwetal 分享 收藏
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Quisinostat is a brain-penetrant radiosensitizer in glioblastoma Lo Cascio, Costanza; Margaryan, Tigran; Luna-Melendez, Ernesto; McNamara, James B.; White, Connor I.; Knight, William; Ganta, Saisrinidhi; Opachich, Zorana; Cantoni, Claudia; Yoo, Wonsuk; Sanai, Nader; Tovmasyan, Artak; Mehta, Shwetal 分享 收藏
A phase 0/Ib study of AZD1390 plus radiotherapy in recurrent glioblastoma patients Sanai, N.; Desai, S.; Margaryan, T.; Lo Cascio, C.; Elliott, M.; Molloy, J.; Harmon, J.; Hong, A.; Melendez, E. Luna; Wanebo, J.; Braun, K.; Kennedy, W.; Garcia, M.; Yoo, W.; Tovmasyan, A.; Tien, A-C.; Mehta, S. N. 分享 收藏
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