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Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect Nicolaou, K. C.; Rigol, Stephan; Pitsinos, Emmanuel N.; Das, Dipendu; Lu, Yong; Rout, Subhrajit; Schammel, Alexander W.; Holte, Dane; Lin, Baiwei; Gu, Christine; Sarvaiya, Hetal; Trinidad, Jose; Barbour, Nicole; Valdiosera, Amanda M.; Sandoval, Joseph; Lee, Christina; Aujay, Monette; Fernando, Hanan; Dhar, Anukriti; Karsunky, Holger; Taylor, Nicole; Pysz, Marybeth; Gavrilyuk, Julia 分享 收藏
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Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis Nicolaou, K. C.; Pan, Saiyong; Pulukuri, Kiran K.; Ye, Qiuji; Rigol, Stephan; Erande, Rohan D.; Vourloumis, Dionisios; Nocek, Boguslaw P.; Munneke, Stefan; Lyssikatos, Joseph; Valdiosera, Amanda; Gu, Christine; Lin, Baiwei; Sarvaiaya, Hetal; Trinidad, Jose; Sandoval, Joseph; Lee, Christina; Hammond, Mikhail; Aujay, Monette; Taylor, Nicole; Pysz, Marybeth; Purcell, James W.; Gavrilyuk, Julia 分享 收藏
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Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues (vol 84, pg 365, 2019) Nicolaou, K. C.; Pulukuri, Kiran Kumar; Rigol, Stephan; Peitsinis, Zisis; Yu, Ruocheng; Kishigami, Satoshi; Cen, Nicholas; Aujay, Monette; Sandoval, Joseph; Zepeda, Nancy; Gavrilyuk, Julia 分享 收藏
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Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues Nicolaou, K. C.; Pulukuri, Kiran Kumar; Rigol, Stephan; Peitsinis, Zisis; Yu, Ruocheng; Kishigami, Satoshi; Cen, Nicholas; Aujay, Monette; Sandoval, Joseph; Zepeda, Nancy; Gavrilyuk, Julia 分享 收藏
Enantioselective Total Synthesis of Antibiotic CJ-16,264, Synthesis and Biological Evaluation of Designed Analogues, and Discovery of Highly Potent and Simpler Antibacterial Agents Nicolaou, K. C.; Pulukuri, Kiran Kumar; Rigol, Stephan; Buchman, Marek; Shah, Akshay A.; Cen, Nicholas; McCurry, Megan D.; Beabout, Kathryn; Shamoo, Yousif 分享 收藏
Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues Nicolaou, K. C.; Chen, Pengxi; Zhu, Shugao; Cai, Quan; Erande, Rohan D.; Li, Ruofan; Sun, Hongbao; Pulukuri, Kiran Kumar; Rigol, Stephan; Aujay, Monette; Sandoval, Joseph; Gavrilyuk, Julia 分享 收藏
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Synthesis and Biological Investigation of Δ12-Prostaglandin J3 (Δ12-PGJ3) Analogues and Related Compounds Nicolaou, K. C.; Pulukuri, Kiran Kumar; Rigol, Stephan; Heretsch, Philipp; Yu, Ruocheng; Grove, Charles I.; Hale, Christopher R. H.; ElMarrouni, Abdelatif; Fetz, Verena; Broenstrup, Mark; Aujay, Monette; Sandoval, Joseph; Gavrilyuk, Julia 分享 收藏
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