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BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model BRCA1/Trp53杂合性和复制应激在小鼠模型中驱动食管癌的发展 He, Ye; Rivera, Joshua; Diossy, Miklos; Duan, Haohui; Bowman-Colin, Christian; Reed, Rachel; Jennings, Rebecca; Novak, Jesse; Tran, Stevenson, V; Cohen, Elizabeth F.; Szuts, David; Giobbie-Hurder, Anita; Bronson, Roderick T.; Bass, Adam J.; Signoretti, Sabina; Szallasi, Zoltan; Livingston, David M.; Pathania, Shailja 分享 收藏
BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage Vohhodina, Jekaterina; Goehring, Liana J.; Liu, Ben; Kong, Qing; Botchkarev, Vladimir V.; Huynh, Mai; Liu, Zhiqi; Abderazzaq, Fieda O.; Clark, Allison P.; Ficarro, Scott B.; Marto, Jarrod A.; Hatchi, Elodie; Livingston, David M. 分享 收藏
RAP80 and BRCA1 PARsylation protect chromosome integrity by preventing retention of BRCA1-B/C complexes in DNA repair foci Vohhodina, Jekaterina; Toomire, Kimberly J.; Petit, Sarah A.; Micevic, Goran; Kumari, Geeta; Botchkarev, Vladimir V., Jr.; Li, Zhe; Livingston, David M.; Hu, Yiduo 分享 收藏
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation Li, Andrew G.; Murphy, Elizabeth C.; Culhane, Aedin C.; Powell, Emily; Wang, Hua; Bronson, Roderick T.; Thanh Von; Giobbie-Hurder, Anita; Gelman, Rebecca S.; Briggs, Kimberly J.; Piwnica-Worms, Helen; Zhao, Jean J.; Kung, Andrew L.; Kaelin, William G., Jr.; Livingston, David M. 分享 收藏
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BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells Wang, Hua; Bierie, Brian; Li, Andrew G.; Pathania, Shailja; Toomire, Kimberly; Dimitrov, Stoil D.; Liu, Ben; Gelman, Rebecca; Giobbie-Hurder, Anita; Feunteun, Jean; Polyak, Kornelia; Livingston, David M. 分享 收藏
Excellent translational research in oncology: A journey towards novel and more effective anti-cancer therapies Rajan, A.; Berns, A.; Ringborg, U.; Celis, J.; Ponder, B.; Caldas, C.; Livingston, D.; Bristow, R. G.; Hecht, T. T.; Tursz, T.; van Luenen, H.; Bono, P.; Helander, T.; Searnon, K.; Smyth, J. F.; Louvard, D.; Eggermont, A.; van Harten, W. H. 分享 收藏
Defective stalled replication fork repair and predisposition to hereditary breast cancer Pathania, Shailja; Bade, Sangeeta; Le Guillou, Morwenna; Burke, Karly; Su, Ying; Ting, David T.; Polyak, Kornelia; Richardson, Andrea L.; Feunteun, Jean; Garber, Judy E.; Livingston, David M. 分享 收藏
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Papillomavirus E7 Oncoproteins Share Functions with Polyomavirus Small T Antigens White, Elizabeth A.; Kramer, Rebecca E.; Hwang, Justin H.; Fernando, Arun T. Pores; Naetar, Nana; Hahn, William C.; Roberts, Thomas M.; Schaffhausen, Brian S.; Livingston, David M.; Howley, Peter M. 分享 收藏
BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair Hatchi, Elodie; Skourti-Stathaki, Konstantina; Ventz, Steffen; Pinello, Luca; Yen, Angela; Kamieniarz-Gdula, Kinga; Dimitrov, Stoil; Pathania, Shailja; McKinney, Kristine M.; Eaton, Matthew L.; Kellis, Manolis; Hill, Sarah J.; Parmigiani, Giovanni; Proudfoot, Nicholas J.; Livingston, David M. 分享 收藏
An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma 肿瘤内遗传筛查显示，BET溴结构域蛋白BRD4是卵巢癌的潜在治疗靶点。 Baratta, Maria Giuseppina; Schinzel, Anna C.; Zwang, Yaara; Bandopadhayay, Pratiti; Bowman-Colin, Christian; Kutt, Jennifer; Curtis, Jennifer; Piao, Huiying; Wong, Laura C.; Kung, Andrew L.; Beroukhim, Rameen; Bradner, James E.; Drapkin, Ronny; Hahn, William C.; Liu, Joyce F.; Livingston, David M. 分享 收藏
PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination-Mediated DNA Repair Hu, Yiduo; Petit, Sarah A.; Ficarro, Scott B.; Toomire, Kimberly J.; Xie, Anyong; Lim, Elgene; Cao, Shiliang A.; Park, Eunyoung; Eck, Michael J.; Scully, Ralph; Brown, Myles; Marto, Jarrod A.; Livingston, David M. 分享 收藏
BRCA1 haploinsufficiency for replication stress suppression in primary cells Pathania, Shailja; Bade, Sangeeta; Le Guillou, Morwenna; Burke, Karly; Reed, Rachel; Bowman-Colin, Christian; Su, Ying; Ting, David T.; Polyak, Kornelia; Richardson, Andrea L.; Feunteun, Jean; Garber, Judy E.; Livingston, David M. 分享 收藏
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