Michael R. Erdos - Publications, H-index & Citations

Michael R. Erdos

National Human Genome Research Institute

75H指数

200论文数

3.9W被引数

收录论文 80

发表时间

In Vivo Base Editing Partially Rescues Bone Dysplasia in a Mouse Model of Hutchinson-Gilford Progeria Syndrome 体内碱基编辑部分挽救 Hutchinson-Gilford 早衰综合征小鼠模型的骨发育不良

Aging Cell

IF7.1

2026-09-04

OAAI

Wayne A. Cabral; Caleb M. Grenko; Diana Yeritsyan; Indeevar Beeram; Shubham Laiwala; Lukas R. Johnson; Urraca L. Tavarez; Tingfen Yan; Stephen M. Wincovitch; Luke W. Koblan; Xin D. Gao; Meirui An; Narisu Narisu; Leslie G. Biesecker; David R. Liu; Ara Nazarian; Francis S. Collins; Michael R. Erdos

Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits 骨骼肌eQTL荟萃分析表明基因与肌肉和 cardiometabolic 特征的遗传结构相关

The American Journal of Human Genetics

IF0

2025-09-23

OAAI

Emma P. Wilson; K. Alaine Broadaway; Victoria A. Parsons; Swarooparani Vadlamudi; Narisu Narisu; Sarah M. Brotman; Kevin W. Currin; Heather M. Stringham; Michael R. Erdos; Ryan Welch; Jeffrey K. Holtzman; Timo A. Lakka; Markku Laakso; Jaakko Tuomilehto; Michael Boehnke; Heikki A. Koistinen; Francis S. Collins; Stephen C.J. Parker; Laura J. Scott; Karen L. Mohlke

A spatial transcriptomics dataset of pancreas sections in normal glucose tolerance and type 2 diabetic donors 正常葡萄糖耐量和2型糖尿病供者的胰腺切片空间转录组学数据集

Scientific Data

IF6.9

2025-09-01

OAAI

Nick Howell; Zoe Weiss; Lori L. Bonnycastle; Caleb M. Grenko; Davide Randazzo; Christopher H. Dampier; Neelam Sinha; Narisu Narisu; Amy J. Swift; Michael R. Erdos; Leslie G. Biesecker; Francis S. Collins; Catherine C. Robertson; D. Leland Taylor

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals 整合性单细胞多组学分析人类胰腺胰岛，鉴定1型糖尿病相关基因及调控信号

Cell Reports

IF6.9

2025-07-29

OAAI

Ricardo D'Oliveira Albanus; Xiaoshan Zhang; Zeping Zhao; Henry J. Taylor; Xuming Tang; Yuling Han; Peter Orchard; Arushi Varshney; Tuo Zhang; Nandini Manickam; Michael R. Erdos; Narisu Narisu; Leland Taylor; Xiaxia Saavedra; Xinyi Liu; Aaron Zhong; Bo Li; Ting Zhou; Ali Naji; Chengyang Liu; Francis S. Collins; Stephen C.J. Parker; Shuibing Chen

Extensive differential gene expression and regulation by sex in human skeletal muscle 性別对人类骨骼肌广泛差异基因表达和调控的影响

Cell Genomics

IF9

2025-06-05

OAAI

Sarah C. Hanks; Abigail S. Mauger; Arushi Varshney; Dan L. Ciotlos; Nandini Manickam; Narisu Narisu; Alexandria J. Shumway; Peter Orchard; Michael R. Erdos; Michael D. Sweeney; Jeffrey Okamoto; Anne U. Jackson; Heather M. Stringham; Lori L. Bonnycastle; Xiang Zhou; Timo A. Lakka; Karen L. Mohlke; Jaakko Tuomilehto; Markku Laakso; Michael Boehnke; Praveen Sethupathy; Francis S. Collins; Heikki A. Koistinen; Stephen C.J. Parker; Laura J. Scott

Characterization of the craniofacial abnormalities of the homozygous G608G progeria mouse model

FRONTIERS IN PHYSIOLOGY

IF3.4

2024-11-06

OAAI

Beeram, Indeevar; Cubria, Maria Belen; Kamalapathy, Pramod; Yeritsyan, Diana; Dubose, Amanda J.; Razavi, Ahmad Hedayatzadeh; Nafisi, Nazanin; Erdos, Michael R.; Snyder, Brian D.; Cabral, Wayne A.; Collins, Francis S.; Nazarian, Ara

Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature

AGING CELL

IF7.1

2024-10-18

OAAI

Vakili, Sahar; Izydore, Elizabeth K.; Losert, Leonhard; Cabral, Wayne A.; Tavarez, Urraca L.; Shores, Kevin; Xue, Huijing; Erdos, Michael R.; Truskey, George A.; Collins, Francis S.; Cao, Kan

Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h

DIABETOLOGIA

IF10.2

2024-07-05

OAAI

Grenko, Caleb M.; Taylor, Henry J.; Bonnycastle, Lori L.; Xue, Dongxiang; Lee, Brian N.; Weiss, Zoe; Yan, Tingfen; Swift, Amy J.; Mansell, Erin C.; Lee, Angela; Robertson, Catherine C.; Narisu, Narisu; Erdos, Michael R.; Chen, Shuibing; Collins, Francis S.; Taylor, D. Leland

Previously Frozen Beta-Cell Transcriptional Response to Cytokine Treatment Mirrors That of Fresh Beta Cells

DIABETES

IF7.5

2024-06-14

PREAI

Orchard, Peter; Wang, Xiaoou; Yan, Tingfen; Narisu, Narisu; Robertson, Cassie; Erdos, Michael; Meng, Jerry; Collins, Francis S.; Chen, Shuibing; Parker, Stephen C.

Multiome Profiling of Human Islets Nominates Beta-CellSpecific Cytokine Response Profiles Underlying Type 1 Diabetes

DIABETES

IF7.5

2024-06-14

PREAI

Robertson, Cassie; Wang, Xiaoou; Orchard, Peter; Meng, Jerry; Dolgachev, Vladislav; Manickam, Nandini; Narisu, Narisu; Erdos, Michael; Collins, Francis S.; Chen, Shuibing; Parker, Stephen C.

Differential Cell-Type-Specific Gene Expression and Chromatin Accessibility by Type 2 Diabetes Status and Physical Activity Levels in Human Skeletal Muscle

DIABETES

IF7.5

2024-06-14

PREAI

Ciotlos, Dan; Hanks, Sarah; Varshney, Arushi; Erdos, Michael; Manickam, Nandini; Stringham, Heather M.; Hill-Burns, Erin; Orchard, Peter; Narisu, Narisu; Bonnycastle, Lori L.; Sweeney, Michael D.; Laakso, Markku, Sr.; Tuomilehto, Jaakko; Lakka, Timo A.; Mohlke, Karen L.; Boehnke, Michael; Koistinen, Heikki A.; Collins, Francis S.; Parker, Stephen; Scott, Laura

Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing

CRISPR JOURNAL

IF4

2024-02-01

OAAI

Bonnycastle, Lori L.; Swift, Amy J.; Mansell, Erin C.; Lee, Angela; Winnicki, Elizabeth; Li, Elizabeth S.; Robertson, Catherine C.; Parsons, Victoria A.; Huynh, Trung; Krilow, Chad; Mohlke, Karen L.; Erdos, Michael R.; Narisu, Narisu; Collins, Francis S.

Normal Bone Matrix Mineralization but Altered Growth Plate Morphology in the LmnaG609G/G609G Mouse Model of Progeria

AGING AND DISEASE

IF6.9

2024-01-01

OAAI

Blouin, Stephane; Hartmann, Markus A.; Fratzl-Zelman, Nadja; Messmer, Phaedra; Whisenant, Daniel; Erdos, Michael R.; Collins, Francis S.; Eriksson, Maria; Strandgren, Charlotte; Cabral, Wayne A.; Dechat, Thomas

Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived I3-like cells

CELL METABOLISM

IF30.9

2023-11-01

OAAI

Xue, Dongxian; Narisu, Narisu; Taylor, D. Leland; Zhang, Meili; Grenko, Caleb; Taylor, Henry J.; Yan, Tingfen; Tang, Xuming; Sinha, Neelam; Zhu, Jiajun; Vandana, J. Jeya; Chong, Angie Chi Nok; Lee, Angela; Mansell, Erin C.; Swift, Amy J.; Erdos, Michael R.; Zhong, Aaron; Bonnycastle, Lori L.; Zhou, Ting; Chen, Shuibing; Collins, Francis S.

Bone dysplasia in Hutchinson-Gilford progeria syndrome is associated with dysregulated differentiation and function of bone cell populations Hutchinson-gilford progeria综合征的骨发育异常与骨细胞群的分化和功能失调有关

AGING CELL

IF7.1

2023-06-26

OAAI

Cabral, Wayne A.; Stephan, Chris; Terajima, Masahiko; Thaivalappil, Abhirami A.; Blanchard, Owen; Tavarez, Urraca L.; Narisu, Narisu; Yan, Tingfen; Wincovitch, Stephen M.; Taga, Yuki; Yamauchi, Mitsuo; Kozloff, Kenneth M.; Erdos, Michael R.; Collins, Francis S.

ADA Presidents' Select Abstract: An Isogenic hPSC-Based Platform for Functional Interrogation of the Role of Multiple T2D-Associated Genes in Pancreatic Beta-Cell Failure

DIABETES

IF7.5

2023-06-20

PREAI

Xue, Dongxiang; Narisu, Narisu; Yan, Tingfen; Zhang, Meili; Grenko, Caleb; Tang, Xuming; Zhu, Jiajun; Bonnycastle, Lori L.; Erdos, Michael; Vandana, J. Jeya; Chong, Angie; Collins, Francis S.; Chen, Shuibing

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake 全基因组关联研究和功能表征确定胰岛素刺激葡萄糖摄取的候选基因

NATURE GENETICS

IF31.8

2023-06-08

OAAI

Williamson, Alice; Norris, Dougall M.; Yin, Xianyong; Broadaway, K. Alaine; Moxley, Anne H.; Vadlamudi, Swarooparani; Wilson, Emma P.; Jackson, Anne U.; Ahuja, Vasudha; Andersen, Mette K.; Arzumanyan, Zorayr; Bonnycastle, Lori L.; Bornstein, Stefan R.; Bretschneider, Maxi P.; Buchanan, Thomas A.; Chang, Yi-Cheng; Chuang, Lee-Ming; Chung, Ren-Hua; Clausen, Tine D.; Damm, Peter; Delgado, Graciela E.; de Mello, Vanessa D.; Dupuis, Josee; Dwivedi, Om P.; Erdos, Michael R.; Silva, Lilian Fernandes; Frayling, Timothy M.; Gieger, Christian; Goodarzi, Mark O.; Guo, Xiuqing; Gustafsson, Stefan; Hakaste, Liisa; Hammar, Ulf; Hatem, Gad; Herrmann, Sandra; Hojlund, Kurt; Horn, Katrin; Hsueh, Willa A.; Hung, Yi-Jen; Hwu, Chii-Min; Jonsson, Anna; Karhus, Line L.; Kleber, Marcus E.; Kovacs, Peter; Lakka, Timo A.; Lauzon, Marie; Lee, I-Te; Lindgren, Cecilia M.; Lindstrom, Jaana; Linneberg, Allan; Liu, Ching-Ti; Luan, Jian'an; Aly, Dina Mansour; Mathiesen, Elisabeth; Moissl, Angela P.; Morris, Andrew P.; Narisu, Narisu; Perakakis, Nikolaos; Peters, Annette; Prasad, Rashmi B.; Rodionov, Roman N.; Roll, Kathryn; Rundsten, Carsten F.; Sarnowski, Chloe; Savonen, Kai; Scholz, Markus; Sharma, Sapna; Stinson, Sara E.; Suleman, Sufyan; Tan, Jingyi; Taylor, Kent D.; Uusitupa, Matti; Vistisen, Dorte; Witte, Daniel R.; Walther, Romy; Wu, Peitao; Xiang, Anny H.; Zethelius, Bjorn; Ahlqvist, Emma; Bergman, Richard N.; Chen, Yii-Der Ida; Collins, Francis S.; Fall, Tove; Florez, Jose C.; Fritsche, Andreas; Grallert, Harald; Groop, Leif; Hansen, Torben; Koistinen, Heikki A.; Komulainen, Pirjo; Laakso, Markku; Lind, Lars; Loeffler, Markus; Maerz, Winfried; Meigs, James B.; Raffel, Leslie J.; Rauramaa, Rainer; Rotter, Jerome I.; Schwarz, Peter E. H.; Stumvoll, Michael; Sundstrom, Johan; Toenjes, Anke; Tuomi, Tiinamaija; Tuomilehto, Jaakko; Wagner, Robert; Barroso, Ines; Walker, Mark; Grarup, Niels; Boehnke, Michael; Wareham, Nicholas J.; Mohlke, Karen L.; Wheeler, Eleanor; O'Rahilly, Stephen; Fazakerley, Daniel J.; Langenberg, Claudia

Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-02-09

OAAI

Taylor, Henry J.; Hung, Yu-Han; Narisu, Narisu; Erdos, Michael R.; Kanke, Matthew; Yan, Tingfen; Grenko, Caleb M.; Swift, Amy J.; Bonnycastle, Lori L.; Sethupathy, Praveen; Collins, Francis S.; Taylor, D. Leland

Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk 整合转录组学、代谢组学和gw有助于揭示代谢物水平和疾病风险的分子机制

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-10-01

OAAI

Yin, Xianyong; Bose, Debraj; Kwon, Annie; Hanks, Sarah C.; Jackson, Anne U.; Stringham, Heather M.; Welch, Ryan; Oravilahti, Anniina; Silva, Lilian Fernandes; Locke, FinnGen Adam E.; Fuchsberger, Christian; Service, Susan K.; Erdos, Michael R.; Bonnycastle, Lori L.; Kuusisto, Johanna; Stitziel, Nathan O.; Hall, Ira M.; Morrison, Jean; Ripatti, Samuli; Palotie, Aarno; Freimer, Nelson B.; Collins, Francis S.; Mohlke, Karen L.; Scott, Laura J.; Fauman, Eric B.; Burant, Charles; Boehnke, Michael; Laakso, Markku; Wen, Xiaoquan

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci 芬兰男性代谢物的全基因组关联研究确定了与疾病相关的基因座

NATURE COMMUNICATIONS

IF15.7

2022-03-28

OAAI

Yin, Xianyong; Chan, Lap Sum; Bose, Debraj; Jackson, Anne U.; VandeHaar, Peter; Locke, Adam E.; Fuchsberger, Christian; Stringham, Heather M.; Welch, Ryan; Yu, Ketian; Silva, Lilian Fernandes; Service, Susan K.; Zhang, Daiwei; Hector, Emily C.; Young, Erica; Ganel, Liron; Das, Indraniel; Abel, Haley; Erdos, Michael R.; Bonnycastle, Lori L.; Kuusisto, Johanna; Stitziel, Nathan O.; Hall, Ira M.; Wagner, Gregory R.; Kang, Jian; Morrison, Jean; Burant, Charles F.; Collins, Francis S.; Ripatti, Samuli; Palotie, Aarno; Freimer, Nelson B.; Mohlke, Karen L.; Scott, Laura J.; Wen, Xiaoquan; Fauman, Eric B.; Laakso, Markku; Boehnke, Michael

研究方向