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RNAi Screening in Tumor Cells Identifies Artificial microRNAs That Improve Oncolytic Virus Replication RNAi筛选在肿瘤细胞中鉴定出能够增强溶瘤病毒复制的工程microRNAs Klemets, Hannah; Bardoul, Angelina; Pelin, Adrian; Singaravelu, Ragunath; Boileau, Meaghan; Falls, Theresa; Petryk, Julia; Bourgeois-Daigneault, Marie-Claude; Bell, John C.; Roy, Dominic G. 分享 收藏
Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment (vol 15, 1500570, 2024) 通过细胞外囊泡介导的微小RNA重编程肿瘤微环境以增强溶瘤病毒疗法 (vol 15, 1500570, 2024) Jennings, Victoria A.; Rumbold-Hall, Reah; Migneco, Gemma; Barr, Tyler; Reilly, Katrina; Ingram, Nicola; Hilare, Isabelle St; Heaton, Samuel; Alzamel, Noura; Jackson, David; Ralph, Christy; Banerjee, Susan; McNeish, Iain; Bell, John C.; Melcher, Alan A.; Ilkow, Carolina; Cook, Graham P.; Errington-Mais, Fiona 分享 收藏
Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprograming of the tumour microenvironment 通过细胞外囊泡介导的microRNA重新编程肿瘤微环境来增强溶瘤病毒治疗 Jennings, Victoria A.; Rumbold-Hall, Reah; Migneco, Gemma; Barr, Tyler; Reilly, Katrina; Ingram, Nicola; St Hilare, Isabelle; Heaton, Samuel; Alzamel, Noura; Jackson, David; Ralph, Christy; Banerjee, Susan; Mcneish, Iain; Bell, John C.; Melcher, Alan A.; Ilkow, Carolina; Cook, Graham P.; Errington-Mais, Fiona 分享 收藏
Antibiotic-mediated selection of randomly mutagenized and cytokine-expressing oncolytic viruses 抗生素介导的随机诱变和表达细胞因子的溶瘤病毒的选择 Rezaei, Reza; Boulton, Stephen; Ahmadi, Mahsa; Petryk, Julia; Da Silva, Miles; Kooshki Zamani, Nika; Singaravelu, Ragunath; St-Laurent, Gabriel; Daniel, Lauren; Sadeghipour, Arezoo; Pelin, Adrian; Poutou, Joanna; Munoz Zuniga, Abril Ixchel; Choy, Clarence; Gilchrist, Victoria H.; Khalid, Zumama; Austin, Bradley; Onsu, Kemal Alper; Marius, Ricardo; Ameli, Zahra; Mohammadi, Fazel; Mancinelli, Valeria; Wang, Emily; Nik-Akhtar, Abolfazl; Alwithenani, Akram; Panahi Arasi, Fatemeh; Ferguson, Stephen S. G.; Hobman, Tom C.; Alain, Tommy; Tai, Lee-Hwa; Ilkow, Carolina S.; Diallo, Jean-Simon; Bell, John C.; Azad, Taha 分享 收藏
Real-world utility of whole genome sequencing for patients with cancer: Evaluation of a regional implementation of the 100,000 genomes project 癌症患者全基因组测序的现实应用：对“100,000 Genomes Project”区域性实施的评价 Robbins, H. L.; Leung, E.; Zaman, S.; Lal, N.; Morton, D.; Dew, L.; Williams, A.; Wallis, Y.; Bell, J.; Raghavan, M.; Middleton, G.; Beggs, A. D. 分享 收藏
Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy Taha, Zaid; Crupi, Mathieu Joseph Francois; Alluqmani, Nouf; Mackenzie, Duncan; Vallati, Sydney; Whelan, Jack Timothy; Fareez, Faiha; Alwithenani, Akram; Petryk, Julia; Chen, Andrew; Spinelli, Marcus Mathew; Ng, Kristy; Sobh, Judy; de Souza, Christiano Tanese; Bharadwa, Priya Rose; Lee, Timothy Kit Hin; Thomas, Dylan Anthony; Huang, Ben Zhen; Kassas, Omar; Poutou, Joanna; Gilchrist, Victoria Heather; Boulton, Stephen; Thomson, Max; Marius, Ricardo; Hooshyar, Mohsen; Mccomb, Scott; Arulanandam, Rozanne; Ilkow, Carolina Solange; Bell, John Cameron; Diallo, Jean-Simon 分享 收藏
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling Armstrong, Edward; Chiu, Matthew K. L.; Foo, Shane; Appleton, Lizzie; Nenclares, Pablo; Patrikeev, Anton; Mohan, Nitya; Mclaughlin, Martin; Bozhanova, Galabina; Hoebart, Julia; Roulstone, Victoria; Patin, Emmanuel; Pedersen, Malin; Kyula, Joan; Ono, Masahiro; Errington-Mais, Fiona; Bell, John; Harrington, Kevin J.; Melcher, Alan; Jennings, Victoria 分享 收藏
PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway Hodgins, Jonathan J.; Abou-Hamad, John; O'Dwyer, Colin Edward; Hagerman, Ash; Yakubovich, Edward; Tanese de Souza, Christiano; Marotel, Marie; Buchler, Ariel; Fadel, Saleh; Park, Maria M.; Fong-McMaster, Claire; Crupi, Mathieu F.; Makinson, Olivia Joan; Kurdieh, Reem; Rezaei, Reza; Dhillon, Harkirat Singh; Ilkow, Carolina S.; Bell, John C.; Harper, Mary-Ellen; Rotstein, Benjamin H.; Auer, Rebecca C.; Vanderhyden, Barbara C.; Sabourin, Luc A.; Bourgeois-Daigneault, Marie-Claude; Cook, David P.; Ardolino, Michele 分享 收藏
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Defective STING signaling in low-grade serous ovarian cancer: an opportunity for oncolytic viruses therapy Zhantuyakova, Almira; Cochrane, Dawn; Negri, Gian Luca; Miko, Sandra Spencer; Azad, Taha; Fernandez, Marta Llaurado; Carey, Mark; Morin, Gregg B.; Bell, John; Huntsman, David D. 分享 收藏
Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development Boulton, Stephen; Crupi, Mathieu J. F.; Singh, Siddharth; Carter-Timofte, Madalina E.; Azad, Taha; Organ, Bailey C.; He, Xiaohong; Gill, Rida; Neault, Serge; Jamieson, Taylor; Dave, Jaahnavi; Kurmasheva, Naziia; Austin, Bradley; Petryk, Julia; Singaravelu, Ragunath; Huang, Ben Zhen; Franco, Noah; Babu, Kaaviya; Parks, Robin J.; Ilkow, Carolina S.; Olagnier, David; Bell, John C. 分享 收藏
Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies Azad, Taha; Rezaei, Reza; Singaravelu, Ragunath; Pelin, Adrian; Boulton, Stephen; Petryk, Julia; Onsu, Kemal Alper; Martin, Nikolas T.; Hoskin, Victoria; Ghahremani, Mina; Marotel, Marie; Marius, Ricardo; He, Xiaohong; Crupi, Mathieu J. F.; Hoang, Huy-Dung; Nik-Akhtar, Abolfazl; Ahmadi, Mahsa; Zamani, Nika Kooshki; Golshani, Ashkan; Alain, Tommy; Greer, Peter; Ardolino, Michele; Dickinson, Bryan C.; Tai, Lee-Hwa; Ilkow, Carolina S.; Bell, John C. 分享 收藏
Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy Martin, Nikolas T.; Crupi, Mathieu J. F.; Taha, Zaid; Poutou, Joanna; Whelan, Jack T.; Vallati, Sydney; Petryk, Julia; Marius, Ricardo; Austin, Bradley; Azad, Taha; Boulanger, Mason; Burgess, Tamara; Sanders, Ilson; Victoor, Camille; Dickinson, Bryan C.; Diallo, Jean-Simon; Ilkow, Carolina S.; Bell, John C. 分享 收藏
Syngeneic mouse model of human HER2+metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus Taha, Zaid; Crupi, Mathieu J. F.; Alluqmani, Nouf; Fareez, Faiha; Ng, Kristy; Sobh, Judy; Lee, Emily; Chen, Andrew; Thomson, Max; Spinelli, Marcus M.; Ilkow, Carolina S.; Bell, John C.; Arulanandam, Rozanne; Diallo, Jean-Simon 分享 收藏
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Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress Blais, Jaime D.; Addison, Christina L.; Edge, Robert; Falls, Theresa; Zhao, Huijun; Wary, Kishore; Koumenis, Costas; Harding, Heather P.; Ron, David; Holcik, Martin; Bell, John C. 分享 收藏
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