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Maintenance rucaparib after first-line platinum-based chemotherapy in advanced esophagogastric (OG) adenocarcinoma: Interim results from the PLATFORM trial Gordon, A.; Fong, C. Y. K.; Davidson, M.; Cromarty, S.; Kidd, S.; Piadel, K.; Peckitt, C.; Satchwell, L.; Rajan, Z.; Begum, R.; Zhitkov, O.; Das, P.; Sothi, S.; Herbertson, R. A.; Darby, S.; Waddell, T. S.; Bradshaw, A.; Starling, N.; Chau, I.; Cunningham, D. 分享 收藏
ctDNA guided adjuvant chemotherapy versus standard of care adjuvant chemotherapy after curative surgery in patients with high risk stage II or stage III colorectal cancer: a multi-centre, prospective, randomised control trial (TRACC Part C) ctDNA指导下的辅助化疗与标准护理辅助化疗在高危II期或III期结直肠癌患者根治性手术后的比较: 一项多中心,前瞻性,随机对照试验 (TRACC C部分) Slater, Susanna; Bryant, Annette; Chen, Hsiang-Chi; Begum, Ruwaida; Rana, Isma; Aresu, Maria; Peckitt, Clare; Zhitkov, Oleg; Lazaro-Alcausi, Retchel; Borja, Victoria; Powell, Rachel; Lowery, David; Hubank, Michael; Rich, Thereasa; Anandappa, Gayathri; Chau, Ian; Starling, Naureen; Cunningham, David 分享 收藏
EMERGE: A phase II trial assessing the efficacy of domatinostat plus avelumab in patients with previously treated advanced mismatch repair proficient oesophagogastric and colorectal cancers - phase IIA dose finding Cartwright, E.; Turkes, F.; Saffery, C.; Tran, A.; Smith, G.; Moreno, S. Esteban; Hatt, S.; Renn, A.; Johnston, E.; Kohoutova, D.; Begum, R.; Smyth, E.; Peckitt, C.; Fribbens, C.; Rao, S.; Watkins, D.; Chau, I.; Starling, N.; Cunningham, D. 分享 收藏
R-GEM-Lenalidomide versus R-GEM-P as second-line treatment of diffuse large B-cell lymphoma: results of the UK NRCI phase II randomised LEGEND trial Kuhnl, Andrea; Peckitt, Clare; Patel, Bijal; Ardeshna, Kirit M.; Macheta, Marian P.; Radford, John; Rod Johnson; Paneesha, Shankaranarayana; Barton, Sarah; Chau, Ian; Begum, Ruwaida; Valeri, Nicola; Wotherspoon, Andrew; Du, Yong; Zerizer, Imene; Cunningham, David 分享 收藏
Influence of sex on chemotherapy efficacy and toxicity in oesophagogastric cancer: A pooled analysis of four randomised trials Davidson, Michael; Wagner, Anna Dorothea; Kouvelakis, Kyriakos; Nanji, Henry; Starling, Naureen; Chau, Ian; Watkins, David; Rao, Sheela; Peckitt, Clare; Cunningham, David 分享 收藏
Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial Khan, Khurum H.; Cunningham, David; Werner, Benjamin; Vlachogiannis, Georgios; Spiteri, Inmaculada; Heide, Timon; Mateos, Javier Fernandez; Vatsiou, Alexandra; Lampis, Andrea; Damavandi, Mahnaz Darvish; Lote, Hazel; Huntingford, Ian Said; Hedayat, Somaieh; Chau, Ian; Tunariu, Nina; Mentrasti, Giulia; Trevisani, Francesco; Rao, Sheela; Anandappa, Gayathri; Watkins, David; Starling, Naureen; Thomas, Janet; Peckitt, Clare; Khan, Nasir; Rugge, Massimo; Begum, Ruwaida; Hezelova, Blanka; Bryant, Annette; Jones, Thomas; Proszek, Paula; Fassan, Matteo; Hahne, Jens C.; Hubank, Michael; Braconi, Chiara; Sottoriva, Andrea; Valeri, Nicola 分享 收藏
Survival in Advanced Esophagogastric Adenocarcinoma Improves With Use of Multiple Lines of Therapy: Results From an Analysis of More Than 500 Patients Davidson, Michael; Cafferkey, Catherine; Goode, Emily Frances; Kouvelakis, Kyriakos; Hughes, Daniel; Reguera, Pablo; Kalaitzaki, Eleftheria; Peckitt, Clare; Rao, Sheela; Watkins, David; Chau, Ian; Cunningham, David; Starling, Naureen 分享 收藏
Molecular subtypes and novel genetic mechanisms of primary and acquired anti-EGFR resistance in colorectal cancer in the Prospect C biomarker trial Khan, Khurum Hayat; Woolston, Andrew; Spain, Georgia; Barber, Louise; Patil, Yatish; Griffiths, Beatrice; GonzalezExposito, Reyes; Mansukhani, Sonia; Davies, Matthew; Rao, Sheela; Watkins, David; Sclafani, Francesco; Suntharanathan, Jana; Peckitt, Clare; Begum, Ruwaida; Rana, Isma; Thomas, Janet; Oates, Jacqui; Bryant, Annette; Wotherspoon, Andrew; Fotiadis, Nicos; Khan, Nasir; Guettler, Sebastian; von Loga, Katharina; Starling, Naureen; Chau, Ian; Sadanandam, Anguraj; Cunningham, David; Gerlinger, Marco 分享 收藏
CHOP versus GEM-P in previously untreated patients with peripheral T-cell lymphoma (CHEMO-T): a phase 2, multicentre, randomised, open-label trial Gleeson, Mary; Peckitt, Clare; To, Ye Mong; Edwards, Laurice; Oates, Jacqueline; Wotherspoon, Andrew; Attygalle, Ayoma D.; Zerizer, Imene; Sharma, Bhupinder; Chua, Sue; Begum, Ruwaida; Chau, Ian; Johnson, Peter; Ardeshna, Kirit M.; Hawkes, Eliza A.; Macheta, Marian P.; Collins, Graham P.; Radford, John; Forbes, Adam; Hart, Alistair; Montoto, Silvia; McKay, Pamela; Benstead, Kim; Morley, Nicholas; Kalakonda, Nagesh; Hasan, Yasmin; Turner, Deborah; Cunningham, David 分享 收藏
Treatment and Survival Outcome of BRAF-Mutated Metastatic Colorectal Cancer: A Retrospective Matched Case-Control Study Kayhanian, Hamzeh; Goode, Emily; Sclafani, Francesco; Ang, Joo Ern; Gerlinger, Marco; de Castro, David Gonzalez; Shepherd, Scott; Peckitt, Clare; Rao, Sheela; Watkins, David; Chau, Ian; Cunningham, David; Starling, Naureen 分享 收藏
Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice Moorcraft, S. Y.; de Castro, D. Gonzalez; Cunningham, D.; Jones, T.; Walker, B. A.; Peckitt, C.; Yuan, L. C.; Frampton, M.; Begum, R.; Eltahir, Z.; Wotherspoon, A.; Mendes, L. S. Teixeira; Wilson, S. Hulkki; Gillbanks, A.; Baratelli, C.; Fotiadis, N.; Patel, A.; Braconi, C.; Valeri, N.; Gerlinger, M.; Rao, S.; Watkins, D.; Chau, I.; Starling, N. 分享 收藏
Comparison between MRI and pathology in the assessment of tumour regression grade in rectal cancer MRI与病理评估直肠癌肿瘤消退程度的比较 Sclafani, Francesco; Brown, Gina; Cunningham, David; Wotherspoon, Andrew; Mendes, Larissa Sena Teixeira; Balyasnikova, Svetlana; Evans, Jessica; Peckitt, Clare; Begum, Ruwaida; Tait, Diana; Tabernero, Josep; Glimelius, Bengt; Rosello, Susana; Thomas, Janet; Oates, Jacqui; Chau, Ian 分享 收藏
Attitudes of Patients With Gastrointestinal Cancers Toward Research Biopsies Moorcraft, Sing Yu; Begum, Ruwaida; Cunningham, David; Peckitt, Clare; Baratelli, Chiara; Gillbanks, Angela; Rogers, Penelope; Nwokorie, Vitalis; Chau, Ian; Watkins, David; Starling, Naureen 分享 收藏
Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial Dalotuzumab在化学难治性KRAS外显子2突变型结直肠癌中的应用: 一项随机II/III期试验的结果 Sclafani, Francesco; Kim, Tae Y.; Cunningham, David; Kim, Tae W.; Tabernero, Josep; Schmoll, Hans J.; Roh, Jae K.; Kim, Sun Y.; Park, Young S.; Guren, Tormod K.; Hawkes, Eliza; Clarke, Stephen J.; Ferry, David; Frodin, Jan-Erik; Ayers, Mark; Nebozhyn, Michael; Peckitt, Clare; Loboda, Andrey; Watkins, David J. 分享 收藏
Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases 血管共同选择介导肝转移对抗血管生成治疗的抗性 Frentzas, Sophia; Simoneau, Eve; Bridgeman, Victoria L.; Vermeulen, Peter B.; Foo, Shane; Kostaras, Eleftherios; Nathan, Mark R.; Wotherspoon, Andrew; Gao, Zu-Hua; Shi, Yu; Van den Eynden, Gert; Daley, Frances; Peckitt, Clare; Tan, Xianming; Salman, Ayat; Lazaris, Anthoula; Gazinska, Patrycja; Berg, Tracy J.; Eltahir, Zak; Ritsma, Laila; van Rheenen, Jacco; Khashper, Alla; Brown, Gina; Nystrom, Hanna; Sund, Malin; Van Laere, Steven; Loyer, Evelyne; Dirix, Luc; Cunningham, David; Metrakos, Peter; Reynolds, Andrew R. 分享 收藏
Investigating the feasibility of precision medicine in gastrointestinal cancers 探讨精准医学在胃肠道肿瘤中的可行性 Moorcraft, S. Y.; De Castro, D. Gonzalez; Cunningham, D.; Walker, B.; Jones, T.; Peckitt, C.; Wilson, S. Hulkki; Wotherspoon, A.; Mendes, L. S. Teixeira; Begum, R.; Eltahir, Z.; Yuan, L.; Gillbanks, A.; Baratelli, C.; Valeri, N.; Gerlinger, M.; Braconi, C.; Chau, I.; Watkins, D.; Starling, N. 分享 收藏
A study of motivations and expectations of patients seen in phase 1 oncology clinics Dolly, Saoirse O.; Kalaitzaki, Eleftheria; Puglisi, Martina; Stimpson, Sarah; Hanwell, Janet; Fandos, Sonia Serrano; Stapleton, Sarah; Ansari, Thushara; Peckitt, Clare; Kaye, Stan; Lopez, Juanita; Yap, Timothy A.; van der Graaf, Winette; de Bono, Johann; Banerji, Udai 分享 收藏
PAN-EX: a pooled analysis of two trials of neoadjuvant chemotherapy followed by chemoradiotherapy in MRI-defined, locally advanced rectal cancer Sclafani, F.; Brown, G.; Cunningham, D.; Wotherspoon, A.; Tait, D.; Peckitt, C.; Evans, J.; Yu, S.; Teixeira Mendes, L. Sena; Tabernero, J.; Glimelius, B.; Cervantes, A.; Thomas, J.; Begum, R.; Oates, J.; Chau, I. 分享 收藏
High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial Pearson, Alex; Smyth, Elizabeth; Babina, Irina S.; Herrera-Abreu, Maria Teresa; Tarazona, Noelia; Peckitt, Clare; Kilgour, Elaine; Smith, Neil R.; Geh, Catherine; Rooney, Claire; Cutts, Ros; Campbell, James; Ning, Jian; Fenwick, Kerry; Swain, Amanda; Brown, Gina; Chua, Sue; Thomas, Anne; Johnston, Stephen R. D.; Ajaz, Mazhar; Sumpter, Katherine; Gillbanks, Angela; Watkins, David; Chau, Ian; Popat, Sanjay; Cunningham, David; Turner, Nicholas C. 分享 收藏