David J. Hawellek - Publications, H-index & Citations

David J. Hawellek

roche holding

10H指数

30论文数

1.8K被引数

收录论文 11

发表时间

Quantitative relationship between tominersen concentrations in cerebrospinal fluid and biomarker changes in Huntington's disease patients 脑脊液中tominersen浓度的定量关系与亨廷顿病患者的生物标志物变化

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2025-11-01

OAAI

Yamamoto, Yumi; Silber Baumann, Hanna E.; Bjornsson, Marcus; Grimsey, Paul; Hawellek, David J.; Anderson, Karen; Leavitt, Blair R.; Landwehrmeyer, Bernhard G.; Tabrizi, Sarah; Mccolgan, Peter; Wild, Edward J.; Sanwald Ducray, Patricia

Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice

TRANSLATIONAL NEURODEGENERATION

IF15.2

2024-10-08

OAAI

Caron, Nicholas S.; Byrne, Lauren M.; Lemarie, Fanny L.; Bone, Jeffrey N.; Aly, Amirah E. -E.; Ko, Seunghyun; Anderson, Christine; Casal, Lorenzo L.; Hill, Austin M.; Hawellek, David J.; McColgan, Peter; Wild, Edward J.; Leavitt, Blair R.; Hayden, Michael R.

Tominersen in Adults with Manifest Huntington's Disease

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2023-12-07

OAAI

McColgan, Peter; Thobhani, Alpa; Boak, Lauren; Schobel, Scott A.; Nicotra, Alessia; Palermo, Giuseppe; Trundell, Dylan; Zhou, Julian; Schlegel, Valerie; Ducray, Patricia Sanwald; Hawellek, David J.; Dorn, Jonas; Simillion, Cedric; Lindemann, Michael; Wheelock, Vicki; Durr, Alexandra; Anderson, Karen E.; Long, Jeffrey D.; Wild, Edward J.; Landwehrmeyer, G. Bernhard; Leavitt, Blair R.; Tabrizi, Sarah J.; Doody, Rachelle

Neural representations of the content and production of human vocalization

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-05-30

OAAI

Voigtlaender, Vera A.; Sandhaeger, Florian; Hawellek, David J.; Hage, Steffen R.; Siegel, Markus

Quantifying mutant huntingtin protein in human cerebrospinal fluid to support the development of huntingtin-lowering therapies

SCIENTIFIC REPORTS

IF3.9

2023-04-01

OAAI

Vauleon, Stephanie; Schutz, Katharina; Massonnet, Benoit; Gruben, Nanda; Manchester, Marianne; Buehler, Alessandra; Schick, Eginhard; Boak, Lauren; Hawellek, David J.

CROSS-SECTIONAL EXPLORATION OF THE CLINICAL UTILITY OF BRAIN AGE AS AN IMAGING-BASED MARKER OF DISEASE PATHOLOGY IN HUNTINGTON'S DISEASE (HD) BASED ON THE TOMINERSEN PHASE III TRIAL GENERATION HD 1

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

IF7.5

2022-09-12

PREAI

Hawellek, David J.; Engemann, Denis A.; Holiga, Stefan; Napolitano, Antonio; Abaei, Maryam; McColgan, Peter

Changes in brain activity with tominersen in early-manifest Huntington's disease 早期明显的亨廷顿氏病患者tominersen的大脑活动变化

BRAIN COMMUNICATIONS

IF4.5

2022-06-09

OAAI

Hawellek, D. J.; Garces, P.; Meghdadi, A. H.; Waninger, S.; Smith, A.; Manchester, M.; Schobel, S. A.; Hipp, J. F.