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收藏Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn- glycerol-3-phosphate 2 and overnutrition溶血磷脂酸在1-酰基-sn-甘油-3-磷酸2和营养过剩的大鼠模型中触发肝脏和白色脂肪组织的炎症
Sakuma, Ikki; Gaspar, Rafael C.; Luukkonen, Panu K.; Kahn, Mario; Zhang, Dongyan; Zhang, Xuchen; Murray, Sue; Golla, Jaya Prakash; Vatner, Daniel F.; Samuel, Varman T.; Petersen, Kitt Falk; Shulman, Gerald I. 分享 收藏 Targeting NAD+ metabolism of hepatocellular carcinoma cells by lenvatinib promotes M2 macrophages reverse polarization, suppressing the HCC progressionSun, Qingcan; Shen, Mengying; Zhu, Subin; Liao, Yanxia; Zhang, Dongyan; Sun, Jingyuan; Guo, Zeqin; Wu, Leyuan; Xiao, Lushan; Liu, Li 分享 收藏 Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitisLuukkonen, Panu K.; Sakuma, Ikki; Gaspar, Rafael C.; Mooring, Meghan; Nasiri, Ali; Kahn, Mario; Zhang, Xian-Man; Zhang, Dongyan; Sammalkorpi, Henna; Penttilae, Anne K.; Orho-Melander, Marju; Arola, Johanna; Juuti, Anne; Zhang, Xuchen; Yimlamai, Dean; Yki-Jaervinen, Hannele; Petersen, Kitt Falk; Shulman, Gerald I. 分享 收藏 Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained miceGaspar, Rafael C.; Lyu, Kun; Hubbard, Brandon T.; Leitner, Brooks P.; Luukkonen, Panu K.; Hirabara, Sandro M.; Sakuma, Ikki; Nasiri, Ali; Zhang, Dongyan; Kahn, Mario; Cline, Gary W.; Pauli, Jose Rodrigo; Perry, Rachel J.; Petersen, Kitt F.; Shulman, Gerald I. 分享 收藏 分享 收藏 分享 收藏 Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout miceAbulizi, Abudukadier; Vatner, Daniel F.; Ye, Zhang; Wang, Yongliang; Camporez, Joao-Paulo; Zhang, Dongyan; Kahn, Mario; Lyu, Kun; Sirwi, Alaa; Cline, Gary W.; Hussain, M. Mahmood; Aspichueta, Patricia; Samuel, Varman T.; Shulman, Gerald I. 分享 收藏 OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbanceYang, Yunfan; Li, Xiruo; Luan, Harding H.; Zhang, Bichen; Zhang, Kaisi; Nam, Jin Hyun; Li, Zongyu; Fu, Minnie; Munk, Alexander; Zhang, Dongyan; Wang, Simeng; Liu, Yuyang; Albuquerque, Joao Paulo; Ong, Qunxiang; Li, Rui; Wang, Qi; Robert, Marie E.; Perry, Rachel J.; Chung, Dongjun; Shulman, Gerald, I; Yang, Xiaoyong 分享 收藏 Metabolic control analysis of hepatic glycogen synthesis in vivo体内肝糖原合成的代谢调控分析Nozaki, Yuichi; Petersen, Max C.; Zhang, Dongyan; Vatner, Daniel F.; Perry, Rachel J.; Abulizi, Abudukadier; Haedersdal, Sofie; Zhang, Xian-Man; Butrico, Gina M.; Samuel, Varman T.; Mason, Graeme F.; Cline, Gary W.; Petersen, Kitt F.; Rothman, Douglas L.; Shulman, Gerald I. 分享 收藏 One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspensionBilet, Lena; Phielix, Esther; van de Weijer, Tineke; Gemmink, Anne; Bosma, Madeleen; Moonen-Kornips, Esther; Jorgensen, Johanna A.; Schaart, Gert; Zhang, Dongyan; Meijer, Kenneth; Hopman, Maria; Hesselink, Matthijs K. C.; Ouwens, D. Margriet; Shulman, Gerald I.; Schrauwen-Hinderling, Vera B.; Schrauwen, Patrick 分享 收藏 HRG switches TNFR1-mediated cell survival to apoptosis in Hepatocellular CarcinomaZou, Xuejing; Zhang, Dongyan; Song, Yang; Liu, Shanshan; Long, Qian; Yao, Liheng; Li, Wenwen; Duan, Zhijiao; Wu, Dehua; Liu, Li 分享 收藏 分享 收藏 分享 收藏 Adipose glucocorticoid action influences whole-body metabolism via modulation of hepatic insulin actionAbulizi, Abudukadier; Camporez, Joao-Paulo; Jurczak, Michael J.; Royer, Kasper F.; Zhang, Dongyan; Cline, Gary W.; Samuel, Varman T.; Shulman, Gerald, I; Vatner, Daniel F. 分享 收藏 分享 收藏 Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo (vol 24, pg 1384, 2018)Madiraju, Anila K.; Qiu, Yang; Perry, Rachel J.; Rahimi, Yasmeen; Zhang, Xian-Man; Zhang, Dongyan; Camporez, Joao-Paulo G.; Cline, Gary W.; Butrico, Gina M.; Kemp, Bruce E.; Casals, Gregori; Steinberg, Gregory R.; Vatner, Daniel F.; Petersen, Kitt F.; Shulman, Gerald I. 分享 收藏 Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents乙酰辅酶a羧化酶抑制逆转NAFLD和肝脏胰岛素抵抗，但促进啮齿动物的高甘油三酯血症Goedeke, Leigh; Bates, Jamie; Vatner, Daniel F.; Perry, Rachel J.; Wang, Ting; Ramirez, Ricardo; Li, Li; Ellis, Matthew W.; Zhang, Dongyan; Wong, Kari E.; Beysen, Carine; Cline, Gary W.; Ray, Adrian S.; Shulman, Gerald I. 分享 收藏 Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivoMadiraju, Anila K.; Qiu, Yang; Perry, Rachel J.; Rahimi, Yasmeen; Zhang, Xian-Man; Zhang, Dongyan; Camporez, Joao-Paulo G.; Cline, Gary W.; Butrico, Gina M.; Kemp, Bruce E.; Casals, Gregori; Steinberg, Gregory R.; Vatner, Daniel F.; Petersen, Kitt F.; Shulman, Gerald, I 分享 收藏 Mechanisms by Which Glucagon Acutely Stimulates Hepatic Mitochondrial Oxidation and GluconeogenesisPerry, Rachel J.; Wang, Yongliang; Brill, Allison L.; Peng, Liang; Zhang, Dongyan; Dufour, Sylvie; Zhang, Ye; Zhang, Xian-Man; Nozaki, Yuichi; Cline, Gary; Ehrlich, Barbara E.; Petersen, Kitt; Shulman, Gerald I. 分享 收藏 
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