Daniel Ysselstein - Publications, H-index & Citations

Daniel Ysselstein

swiss institute of bioinformatics

18H指数

48论文数

2.1K被引数

收录论文 23

发表时间

Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons

NEURON

IF15

2023-12-01

PREAI

Song, Pingping; Peng, Wesley; Sauve, Veronique; Fakih, Rayan; Xie, Zhong; Ysselstein, Daniel; Krainc, Talia; Wong, Yvette C.; Mencacci, Niccolo E.; Savas, Jeffrey N.; Surmeier, D. James; Gehring, Kalle; Krainc, Dimitri

Evaluation of Strategies for Measuring Lysosomal Glucocerebrosidase Activity

MOVEMENT DISORDERS

IF7.6

2021-10-06

OAAI

Ysselstein, Daniel; Young, Tiffany J.; Nguyen, Maria; Padmanabhan, Shalini; Hirst, Warren D.; Dzamko, Nicolas; Krainc, Dimitri

Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein

MOLECULAR NEURODEGENERATION

IF17.5

2020-09-08

OAAI

Landeck, Natalie; Strathearn, Katherine E.; Ysselstein, Daniel; Buck, Kerstin; Dutta, Sayan; Banerjee, Siddhartha; Lv, Zhengjian; Hulleman, John D.; Hindupur, Jagadish; Lin, Li-Kai; Padalkar, Sonal; Stanciu, Lia A.; Lyubchenko, Yuri L.; Kirik, Deniz; Rochet, Jean-Christophe

Localization of Fluorescent Targets in Deep Tissue With Expanded Beam Illumination for Studies of Cancer and the Brain

IEEE TRANSACTIONS ON MEDICAL IMAGING

IF9.8

2020-07-01

OAAI

Bentz, Brian Z.; Mahalingam, Sakkarapalayam M.; Ysselstein, Daniel; Montenegro, Paola C.; Cannon, Jason R.; Rochet, Jean-Christophe; Low, Philip S.; Webb, Kevin J.

LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients

NATURE COMMUNICATIONS

IF15.7

2019-12-05

132

OAAI

Ysselstein, Daniel; Nguyen, Maria; Young, Tiffany J.; Severino, Alex; Schwake, Michael; Merchant, Kalpana; Krainc, Dimitri

Progranulin mutations result in impaired processing of prosaposin and reduced glucocerebrosidase activity

HUMAN MOLECULAR GENETICS

IF3.2

2019-10-10

OAAI

Valdez, Clarissa; Ysselstein, Daniel; Young, Tiffany J.; Zheng, Jianbin; Krainc, Dimitri

Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase (vol 63, pg 1218, 2019)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-02-22

OAAI

Zheng, Jianbin; Jeon, Sohee; Jiang, Weilan; Burbulla, Lena F.; Ysselstein, Daniel; Oevel, Kristine; Krainc, Dimitri; Silverman, Richard B.

Emerging links between pediatric lysosomal storage diseases and adult parkinsonism

MOVEMENT DISORDERS

IF7.6

2019-02-06

OAAI

Ysselstein, Daniel; Shulman, Joshua M.; Krainc, Dimitri

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson's Disease

TRENDS IN NEUROSCIENCES

IF15.1

2019-02-01

240

OAAI

Nguyen, Maria; Wong, Yvette C.; Ysselstein, Daniel; Severino, Alex; Krainc, Dimitri

Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-01-15

OAAI

Zheng, Jianbin; Jeon, Sohee; Jiang, Weilan; Burbulla, Lena F.; Ysselstein, Daniel; Oevel, Kristine; Krainc, Dimitri; Silverman, Richard B.

Untangling alpha synuclein fibrils by graphene quantum dots

MOVEMENT DISORDERS

IF7.6

2018-11-28

OAAI

Ysselstein, Daniel; Krainc, Dimitri

β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-04-20

OAAI

Zheng, Jianbin; Chen, Long; Skinner, Owen S.; Ysselstein, Daniel; Remis, Jonathan; Lansbury, Peter; Skerlj, Renato; Mrosek, Michael; Heunisch, Ursula; Krapp, Stephan; Charrow, Joel; Schwake, Michael; Kelleher, Neil L.; Silverman, Richard B.; Krainc, Dimitri

Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies

NATURE COMMUNICATIONS

IF15.7

2017-12-04

OAAI

Conrad, Karen S.; Cheng, Ting-Wen; Ysselstein, Daniel; Heybrock, Saskia; Hoth, Lise R.; Chrunyk, Boris A.; Ende, Christopher W. Am; Krainc, Dimitri; Schwake, Michael; Saftig, Paul; Liu, Shenping; Qiu, Xiayang; Ehlers, Michael D.

Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity Endosulfine-α 抑制膜诱导的 α-突触核蛋白聚集并防止 α-突触核蛋白神经毒性

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2017-01-10

OAAI

Ysselstein, Daniel; Dehay, Benjamin; Costantino, Isabel M.; McCabe, George P.; Frosch, Matthew P.; George, Julia M.; Bezard, Erwan; Rochet, Jean-Christophe

Functional assays for the assessment of the pathogenicity of variants of GOSR2, an ER-to-Golgi SNARE involved in progressive myoclonus epilepsies

DISEASE MODELS & MECHANISMS

IF3.3

2017-01-01

OAAI

Volker, Jorn M.; Dergai, Mykola; Abriata, Luciano A.; Mingard, Yves; Ysselstein, Daniel; Krainc, Dimitri; Dal Peraro, Matteo; von Mollard, Gabriele Fischer; Fasshauer, Dirk; Koliwer, Judith; Schwake, Michael

Printed optics: phantoms for quantitative deep tissue fluorescence imaging (vol 41, pg 5230, 2016)

OPTICS LETTERS

IF3.3

2016-11-29

PREAI

Bentz, Brian Z.; Bowen, Anna G.; Lin, Dergan; Ysselstein, Daniel; Huston, Davin H.; Rochet, Jean-Christophe; Webb, Kevin J.

Printed optics: phantoms for quantitative deep tissue fluorescence imaging

OPTICS LETTERS

IF3.3

2016-11-07

OAAI

Bentz, Brian Z.; Bowen, Anna G.; Lin, Dergan; Ysselstein, Daniel; Huston, Davin H.; Rochet, Jean-Christophe; Webb, Kevin J.

Effect of Acidic pH on the Stability of α-Synuclein Dimers

BIOPOLYMERS

IF3.2

2016-07-22

OAAI

Lv, Zhengjian; Krasnoslobodtsev, Alexey V.; Zhang, Yuliang; Ysselstein, Daniel; Rochet, Jean Christophe; Blanchard, Scott C.; Lyubchenko, Yuri L.

Effect of Acidic pH on the Stability of Alpha-Synuclein Dimers

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Lv, Zhengjian; Krasnoslobodtsev, Alexey V.; Zhang, Yuliang; Ysselstein, Daniel; Rochet, Jean-Christophe; Blanchard, Scott C.; Lyubchenko, Yuri L.

Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity

NEUROBIOLOGY OF DISEASE

IF5.6

2015-07-01

OAAI

Ysselstein, Daniel; Joshi, Mehul; Mishra, Vartika; Griggs, Amy M.; Asiago, Josephat M.; McCabe, George P.; Stanciu, Lia A.; Post, Carol Beth; Rochet, Jean-Christophe

研究方向