Mark Brantly - Publications, H-index & Citations

Mark Brantly

University of Florida

63H指数

275论文数

1.3W被引数

收录论文 87

发表时间

Adaptive Regulation of mTOR Activity by AMPK, Akt, and ATF6 Pathways in Pi*Z Alpha-1 Antitrypsin Deficient Hepatocytes AMPK、Akt和ATF6通路对Pi*Z α-1抗胰蛋白酶缺乏症肝细胞的mTOR活性的适应性调控

Biomolecules

IF4.8

2026-03-30

OAAI

Yuanqing Lu; Jungnam Lee; Naweed Mohammad; Mark L. Brantly

Alpha-defensins promote macrophage inflammatory activation via RNF31 signaling

Genes & Genomics

IF1.7

2026-01-20

PREAI

Jungnam Lee; Naweed Mohammad; Seyoung Mun; Kyudong Han; Tammy Flagg-Dowie; Maria Magallon; Mark L. Brantly; Karina A. Serban

Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults with Alpha-1 Antitrypsin Deficiency-Associated Liver Disease (AATD-LD)关于成人α1-抗胰蛋白酶缺乏相关肝病（AATD-LD）临床评估和临床试验终点的多学会专家小组共识指南

Gastroenterology

IF25.1

2025-12-11

PREAI

Rohit Loomba; Virginia C. Clark; Mattias Mandorfer; Marc Miravitlles; Mark Brantly; Saul J. Karpen; Aleksander Krag; Paul Y. Kwo; Don C. Rockey; Mark W. Russo; Antonio J. Sanchez; Scott Santarella; Suzanne R. Sharpton; Charlie Strange; Jeffrey H. Teckman; Alice M. Turner; Hugo E. Vargas; Pavel Strnad

Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-02-12

OAAI

Lee, Jungnam; Mohammad, Naweed; Han, Kyudong; Flagg-Dowie, Tammy; Magallon, Maria; Brantly, Mark L.; Serban, Karina A.

Plasma Extracellular Vesicle-derived MicroRNA Associated with Human Alpha-1 Antitrypsin Deficiency-mediated Liver Disease

clinical and translational gastroenterology

IF4.2

2024-11-19

OAAI

Oshins, Regina; Huo, Zhiguang; Greenberg, Zachary; Clark, Virginia; Duarte, Sergio; Zhou, Huiping; West, Jesse; He, Mei; Brantly, Mark; Khodayari, Nazli

Liver Characterization of a Cohort of Alpha-1 Antitrypsin Deficiency Patients with and without Lung Disease

clinical and translational gastroenterology

IF4.2

2024-09-14

OAAI

Mohammad, Naweed; Oshins, Regina; Gu, Tongjun; Clark, Virginia; Lascano, Jorge; Assarzadegan, Naziheh; Marek, George; Brantly, Mark; Khodayari, Nazli

Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2024-03-22

PREAI

Loomba, Rohit; Clark, Ginger; Teckman, Jeff; Ajmera, Veeral; Behling, Cynthia; Brantly, Mark; Brenner, David; D'Armiento, Jeanine; Fried, Michael W.; Iyer, Janani S.; Mandorfer, Mattias; Rockey, Don C.; Tincopa, Monica; Vuppalanchi, Raj; Younossi, Zobair; Krag, Aleksander; Turner, Alice M.; Strnad, Pavel

Monocyte NLRP3 inflammasome and interleukin-1β activation modulated by alpha-1 antitrypsin therapy in deficient individuals

THORAX

IF7.7

2024-02-28

OAAI

Gogoi, Debananda; Yu, Howard; Casey, Michelle; Baird, Rory; Yusuf, Azeez; Forde, Luke; O' Brien, Michael E.; West, Jesse R.; Flagg, Tammy; McElvaney, Noel G.; Eden, Edward; Mueller, Christian; Brantly, Mark L.; Geraghty, Patrick; Reeves, Emer P.

Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy

HEPATOLOGY COMMUNICATIONS

IF4.6

2024-02-01

OAAI

Poole, Brittney; Oshins, Regina; Huo, Zhiguang; Aranyos, Alek; West, Jesse; Duarte, Sergio; Clark, Virginia C.; Beduschi, Thiago; Zarrinpar, Ali; Brantly, Mark; Khodayari, Nazli

Treatment for Alpha-1 Antitrypsin Deficiency Does Augmentation Therapy Work?

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2023-11-01

OAAI

Brantly, Mark

Multiplexing AAV Serotype-Specific Neutralizing Antibodies in Preclinical Animal Models and Humans

BIOMEDICINES

IF3.9

2023-02-11

OAAI

Kuoch, Hisae; Krotova, Karina; Graham, Melanie L.; Brantly, Mark L.; Aslanidi, George

Characterization of hepatic inflammatory changes in a C57BL/6J mouse model of alpha1-antitrypsin deficiency

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

IF3.3

2022-12-01

PREAI

Khodayari, Nazli; Oshins, Regina; Aranyos, Alek M.; Duarte, Sergio; Mostofizadeh, Sayedamin; Lu, Yuanqing; Brantly, Mark

Untitled Reply

HEPATOLOGY COMMUNICATIONS

IF4.6

2022-08-26

OAAI

Lu, Yuanqing; Wang, Liqun R.; Lee, Jungnam; Mohammad, Naweed S.; Aranyos, Alek M.; Gould, Calvin; Khodayari, Nazli; Oshins, Regina A.; Moneypenny, Craig G.; Brantly, Mark L.

Alu RNA induces NLRP3 expression through TLR7 activation in α-1-antitrypsin-deficient macrophages

JCI INSIGHT

IF6.1

2022-06-22

OAAI

Lee, Jungnam; Mohammad, Naweed; Lu, Yuanqing; Kang, Keunsoo; Han, Kyudong; Brantly, Mark

The unfolded protein response to PIZ alpha-1 antitrypsin in human hepatocellular and murine models

HEPATOLOGY COMMUNICATIONS

IF4.6

2022-05-27

OAAI

Lu, Yuanqing; Wang, Liqun R.; Lee, Jungnam; Mohammad, Naweed S.; Aranyos, Alek M.; Gould, Calvin; Khodayari, Nazli; Oshins, Regina A.; Moneypenny, Craig G.; Brantly, Mark L.

Nicotine Exacerbates TAAD Formation Induced by Smooth Muscle-Specific Deletion of the TGF-β Receptor 2

JOURNAL OF IMMUNOLOGY RESEARCH

IF3.6

2021-10-01

OAAI

Chun, Changzoon; Qi, Xiaoyan; Wang, Fen; Madrid, Kyle B.; Saldarriaga, Lennon A.; Fisch, Max R.; Brantly, Mark L.; Upchurch, Gilbert R. Jr Jr; Jiang, Zhihua

Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-11-20

OAAI

Lee, Jungnam; Lu, Yuanqing; Oshins, Regina; West, Jesse; Moneypenny, Craig G.; Han, Kyudong; Brantly, Mark L.

Neutrophil elastase promotes macrophage cell adhesion and cytokine production through the integrin-Src kinases pathway

SCIENTIFIC REPORTS

IF3.9

2020-09-28

OAAI

Krotova, Karina; Khodayari, Nazli; Oshins, Regina; Aslanidi, George; Brantly, Mark L.

Alpha-1 antitrypsin deficient individuals have circulating extracellular vesicles with profibrogenic cargo

CELL COMMUNICATION AND SIGNALING

IF8.9

2020-09-04

OAAI

Khodayari, Nazli; Oshins, Regina; Holliday, L. Shannon; Clark, Virginia; Xiao, Qiang; Marek, George; Mehrad, Borna; Brantly, Mark

Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin

JCI INSIGHT

IF6.1

2020-07-23

OAAI

Laffranchi, Mattia; Elliston, Emma L. K.; Miranda, Elena; Perez, Juan; Ronzoni, Riccardo; Jagger, Alistair M.; Heyer-Chauhan, Nina; Brantly, Mark L.; Fra, Annamaria; Lomas, David A.; Irving, James A.

研究方向