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A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides Ali, Malik Zohaib; Dutt, Taru S.; MacNeill, Amy; Walz, Amanda; Pearce, Camron; Lam, Ha; Philp, Jamie S.; Patterson, Johnathan; Henao-Tamayo, Marcela; Lee, Richard; Liu, Jiuyu; Robertson, Gregory T.; Hickey, Anthony J.; Meibohm, Bernd; Juarrero, Mercedes Gonzalez 分享 收藏
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Engineering a muco-trapping ACE2-immunoglobulin hybrid with picomolar affinity as an inhaled, pan-variant immunotherapy for COVID-19 Tiruthani, Karthik; Cruz-Teran, Carlos; Chan, Jasper F. W.; Ma, Alice; Mcsweeney, Morgan; Wolf, Whitney; Yuan, Shoufeng; Poon, Vincent K. M.; Chan, Chris C. S.; Botta, Lakshmi; Farrer, Brian; Stewart, Ian; Schaefer, Alison; Edelstein, Jasmine; Kumar, Priya; Arora, Harendra; Hutchins, Jeff T.; Hickey, Anthony J.; Yuen, Kwok-Yung; Lai, Samuel K. 分享 收藏
Inhaled Muco-Trapping Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections 吸入性黏膜诱捕单克隆抗体可有效治疗已建立的呼吸道合胞病毒 (RSV) 感染 Mcsweeney, Morgan D.; Alnajjar, Sarhad; Schaefer, Alison M.; Richardson, Zach; Wolf, Whitney; Stewart, Ian; Sriboonyapirat, Pun; Mccallen, Justin; Farmer, Ellen; Nzati, Bernadette; Lord, Sam; Farrer, Brian; Moench, Thomas R.; Kumar, Priya A.; Arora, Harendra; Pickles, Raymond J.; Hickey, Anthony J.; Ackermann, Mark; Lai, Samuel K. 分享 收藏
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Tyvaso DPI: Drug-device characteristics and patient clinical considerations McEvoy, Colleen; Argula, Rahul; Sahay, Sandeep; Shapiro, Shelley; Eagan, Christina; Hickey, Anthony J.; Smutney, Chad; Dillon, Chris; Winkler, Thomas; Davis, Brittany N.; Broderick, Meredith; Burger, Charles 分享 收藏
Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics Doherty, Elizabeth L.; Aw, Wen Yih; Warren, Emily C.; Hockenberry, Max; Whitworth, Chloe P.; Krohn, Grace; Howell, Stefanie; Diekman, Brian O.; Legant, Wesley R.; Nia, Hadi Tavakoli; Hickey, Anthony J.; Polacheck, William J. 分享 收藏
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics 用于Spectinamide抗生素临床前开发的简约生理药代动力学 (mPBPK) 模型的开发 Parmar, Keyur R.; Lukka, Pradeep B.; Wagh, Santosh; Temrikar, Zaid H.; Liu, Jiuyu; Lee, Richard E.; Braunstein, Miriam; Hickey, Anthony J.; Robertson, Gregory T.; Gonzalez-Juarrero, Mercedes; Edginton, Andrea; Meibohm, Bernd 分享 收藏
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Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation PIK3CA-driven血管畸形的微生理模型揭示了Rac1和mTORC1/2失调在病变形成中的作用 Aw, Wen Yih; Cho, Crescentia; Wang, Hao; Cooper, Anne Hope; Doherty, Elizabeth L.; Rocco, David; Huang, Stephanie A.; Kubik, Sarah; Whitworth, Chloe P.; Armstrong, Ryan; Hickey, Anthony J.; Griffith, Boyce; Kutys, Matthew L.; Blatt, Julie; Polacheck, William J. 分享 收藏
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization Romano, Lisa E. L.; Aw, Wen Yih; Hixson, Kathryn M.; Novoselova, Tatiana V.; Havener, Tammy M.; Howell, Stefanie; Taylor-Blake, Bonnie; Hall, Charlotte L.; Xing, Lei; Beri, Josh; Nethisinghe, Suran; Perna, Laura; Hatimy, Abubakar; Altadonna, Ginevra Chioccioli; Graves, Lee M.; Herring, Laura E.; Hickey, Anthony J.; Thalassions, Konstantinos; Chapple, J. Paul; Wolter, Justin M. 分享 收藏
Multiple approaches to repurposing drugs for neuroblastoma 神经母细胞瘤药物再利用的多种方法 Rank, Laura; Puhl, Ana C.; Havener, Tammy M.; Anderson, Edward; Foil, Daniel H.; Zorn, Kimberley M.; Monakhova, Natalia; Riabova, Olga; Hickey, Anthony J.; Makarov, Vadim; Ekins, Sean 分享 收藏
Optimization and Scale Up of Spray Dried CPZEN-45 Aerosol Powders for Inhaled Tuberculosis Treatment Stewart, Ian E.; Durham, Phillip G.; Sittenauer, Jacob M.; Barreda, Aranza P.; Stowell, Grayson W.; Moody, Carmella; Mecham, Jeffery B.; Simpson, Catherine; Daily, Sharon; Maloney, Sara E.; Williams, Mark D.; Severynse-Stevens, Diana; Hickey, Anthony J. 分享 收藏
Stable nebulization and muco-trapping properties of regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19 McSweeney, Morgan; Stewart, Ian; Richardson, Zach; Kang, Hyunah; Park, Yoona; Kim, Cheolmin; Tiruthani, Karthik; Wolf, Whitney; Schaefer, Alison; Kumar, Priya; Aurora, Harendra; Hutchins, Jeff; Cho, Jong Moon; Hickey, Anthony J.; Lee, Soo Young; Lai, Samuel 分享 收藏
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COVID-19 symptoms are reduced by targeted hydration of the nose, larynx and trachea George, Carolin Elizabeth; Scheuch, Gerhard; Seifart, Ulf; Inbaraj, Leeberk Raja; Chandrasingh, Sindhulina; Nair, Indu K.; Hickey, Anthony J.; Barer, Michael R.; Fletcher, Eve; Field, Rachel D.; Salzman, Jonathan; Moelis, Nathan; Ausiello, Dennis; Edwards, David A. 分享 收藏
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