David L. Williams - Publications, H-index & Citations

David L. Williams

East Tennessee State University

89H指数

513论文数

2.8W被引数

收录论文 122

发表时间

Heme drives cardiac endothelial senescence in sepsis via STING activation 血红素通过STING活化驱动脓毒症中心脏内皮细胞衰老

Cell Death & Disease

IF9.6

2025-12-18

OAAI

Tingting Li; Peilin Zhu; Jialing Wang; Tao Zhang; Joseph Adams; Fei Tu; Chloe Garbe; Xiaojin Zhang; Li Liu; Krishna Singh; David L. Williams; Chuanfu Li; Xiaohui Wang

In vitro protocol demonstrating five functional steps of trained immunity in mice: Implications on biomarker discovery and translational research 体外实验方案展示小鼠训练免疫的五个功能步骤：对生物标志物发现和转化研究的意义

Cell Reports

IF6.9

2025-09-26

PREAI

Maria González-Pérez; Jana Baranda; Leticia Pérez-Rodríguez; Patricia Conde; Carlos de la Calle-Fabregat; Marcos J. Berges-Buxeda; Alexander Dimitrov; Javier Arranz; Sergio Rius-Rocabert; Alessia Zotta; Ana Dopazo; Nikita Poddar; Xuedi Wang; Estanislao Nistal-Villán; Raphaël Duivenvoorden; Joren C. Madsen; David L. Williams; Dan Hasson; Daniel Lozano-Ojalvo; Florent Ginhoux; Luke A.J. O’Neill; Jordi Ochando

Toll-like receptor 4 induces trained innate immune tolerance in the heart in a model of stress-induced cardiomyopathy Toll-like receptor 4在压力诱导的心肌病模型中诱导心脏获得性固有免疫耐受。

CARDIOVASCULAR RESEARCH

IF13.3

2025-09-01

OAAI

Lim, Kenji Rowel Q.; Amrute, Junedh; Kovacs, Attila; Diwan, Abhinav; Williams, David L.; Mann, Douglas L.

Endothelial HSPA12B regulates myocardial monocyte infiltration and inflammatory activity after myocardial infarction 内皮HSPA12B调节心肌梗死后心肌单核细胞浸润和炎症活性

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-05-15

OAAI

Wang, Yana; Fan, Min; Chen, Linjian; Gill, Patrick Spencer; Wang, Xiaohui; Ha, Tuanzhu; Williams, David L.; Li, Chuanfu; Yang, Kun

Metabolic adaptations driving innate immune memory: mechanisms and therapeutic implications 代谢适应性驱动固有免疫记忆：机制与治疗意义

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2025-03-26

OAAI

Hao, Dan; McBride, Margaret A.; Bohannon, Julia K.; Hernandez, Antonio; Klein, Benjamin; Williams, David L.; Sherwood, Edward R.

Plasmid conjugation drives within-patient plasmid diversity 质粒接合驱动患者内的质粒多样性

MICROBIAL GENOMICS

IF4

2025-03-20

OAAI

Grayson, Fan; Loman, Leo; Nonnenmacher, Toby; Pople, Diane; Pollard, Jack; Patel, Bharat; Williams, David; Hounsome, Luke; Hopkins, Katie L.; Robotham, Julie V.; Ledda, Alice

Dectin-1 stimulating β-glucans inhibit Chlamydia infections both in vitro and in vivo Dectin-1刺激的β-葡聚糖在体外和体内均能抑制沙眼衣原体感染

PATHOGENS AND DISEASE

IF2.7

2025-01-30

PREAI

Kintner, Jennifer; Callaghan, Morgan; Bulawa, Lillith; Chu, Angela; Ma, Zuchao; Williams, David L.; Schoborg, Robert, V; Kruppa, Michael D.; Hall, Jennifer, V

Trained immunity enhances host resistance to infection in aged mice 训练性免疫增强了老年小鼠对感染的宿主抵抗力

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2024-12-26

PREAI

Hao, Dan; Caja, Katherine R.; McBride, Margaret A.; Owen, Allison M.; Bohannon, Julia K.; Hernandez, Antonio; Ali, Sabah; Dalal, Sujata; Williams, David L.

Glycogen synthase activity in Candida albicans is partly controlled by the functional ortholog of Saccharomyces cerevisiae Gac1p

MSPHERE

IF3.1

2024-10-29

OAAI

Miao, Jian; Williams, David L.; Kruppa, Michael D.; Peters, Brian M.

Lactate's impact on immune cells in sepsis: unraveling the complex interplay

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-09-20

OAAI

Zhang, Tao; Chen, Linjian; Kueth, Gatkek; Shao, Emily; Wang, Xiaohui; Ha, Tuanzhu; Williams, David L.; Li, Chuanfu; Fan, Min; Yang, Kun

Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation

NATURE IMMUNOLOGY

IF27.6

2024-04-26

OAAI

Theobald, H.; Bejarano, D. A.; Katzmarski, N.; Haub, J.; Schulte-Schrepping, J.; Yu, J.; Bassler, K.; Ament, A. L.; Osei-Sarpong, C.; Piattini, F.; Vornholz, L.; T'Jonck, W.; Gyoerfi, A. H.; Hayer, H.; Yu, X.; Sheoran, S.; Al Jawazneh, A.; Chakarov, S.; Haendler, K.; Brown, G. D.; Williams, D. L.; Bosurgi, L.; Distler, J. H. W.; Ginhoux, F.; Ruland, J.; Beyer, M. D.; Greter, M.; Bain, C. C.; Vazquez-Armendariz, A. I.; Kopf, M.; Schultze, J. L.; Schlitzer, A.

Candida albicans N-Linked Mannans Potentiate the Induction of Trained Immunity via Dectin-2 白色念珠菌N-连接甘露聚糖通过Dectin-2增强训练免疫的诱导

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2024-03-06

PREAI

Rosati, Diletta; Pradhan, Arnab; van Heck, Julia I. P.; Helder, Leonie; Jaeger, Martin; Gow, Neil A. R.; Joosten, Leo A. B.; Williams, David L.; Brown, Alistair J. P.; Bruno, Mariolina; Netea, Mihai G.

Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity

CELL REPORTS

IF6.9

2024-03-01

OAAI

Santos, Jessica Cristina dos; Moreno, Maria; Teufel, Lisa U.; Chilibroste, Sofia; Keating, Samuel T.; Groh, Laszlo; Dominguez-Andres, Jorge; Williams, David L.; Ma, Zuchao; Lowman, Douglas W.; Ensley, Harry E.; Novakovic, Boris; Ribeiro-Dias, Fatima; Netea, Mihai G.; Chabalgoity, Jose A.; Joosten, Leo A. B.

Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-01-04

OAAI

Keever, Kasey R.; Cui, Kui; Casteel, Jared L.; Singh, Sanjay; Hoover, Donald B.; Williams, David L.; Pavlov, Valentin A.; Yakubenko, Valentin P.

Bacteria- and fungus-derived PAMPs induce innate immune memory via similar functional, metabolic, and transcriptional adaptations 细菌和真菌来源的PAMPs通过相似的功能、代谢和转录适应诱导先天免疫记忆

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2023-10-04

PREAI

Mcbride, Margaret A.; Stothers, Cody L.; Fensterheim, Benjamin A.; Caja, Katherine R.; Owen, Allison M.; Hernandez, Antonio; Bohannon, Julia K.; Patil, Naeem K.; Ali, Sabah; Dalal, Sujata; Rahim, Mohsin; Trenary, Irina A.; Young, Jamey D.; Williams, David L.; Sherwood, Edward R.

Development of Negative Controls for Fc-C-Type Lectin Receptor Probes Fc-c型凝集素受体探针阴性对照的研制

MICROBIOLOGY SPECTRUM

IF3.8

2023-06-15

OAAI

Hatinguais, Remi; Kay, Madalaine; Salazar, Fabian; Conn, Daniel P. P.; Williams, David L. L.; Cook, Peter C. C.; Willment, Janet A. A.; Brown, Gordon D. D.

Glycogen Metabolism in Candida albicans Impacts Fitness and Virulence during Vulvovaginal and Invasive Candidiasis

MBIO

IF4.7

2023-04-25

OAAI

Miao, Jian; Regan, Jessica; Cai, Chun; Palmer, Glen E.; Williams, David L.; Kruppa, Michael D.; Peters, Brian M.

Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction 乳酸通过Snail1乳酸化促进心肌梗死后内皮-间质转化

SCIENCE ADVANCES

IF12.5

2023-02-03

114

OAAI

Fan, Min; Yang, Kun; Wang, Xiaohui; Chen, Linjian; Gill, P. Spencer; Ha, Tuanzhu; Liu, Li; Lewis, Nicole H.; Williams, David L.; Li, Chuanfu

Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

JCI INSIGHT

IF6.1

2023-01-10

OAAI

Saaoud, Fatma; Liu, Lu; Xu, Keman; Cueto, Ramon; Shao, Ying; Lu, Yifan; Sun, Yu; Snyder, Nathaniel W.; Wu, Sheng; Yang, Ling; Zhou, Yan; Williams, David L.; Li, Chuanfu; Martinez, Laisel; Vazquez-Padron, Roberto I.; Zhao, Huaqing; Jiang, Xiaohua; Wang, Hong; Yang, Xiaofeng

Modification of Extracellular Matrix by the Product of DHA Oxidation Switches Macrophage Adhesion Patterns and Promotes Retention of Macrophages During Chronic Inflammation

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-05-26

OAAI

Casteel, Jared L.; Keever, Kasey R.; Ardell, Christopher L.; Williams, David L.; Gao, Detao; Podrez, Eugene A.; Byzova, Tatiana V.; Yakubenko, Valentin P.

研究方向